Q54VK0 (Q54VK0_DICDI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase EMBL EAL67372.1

Gene names

ORF Names:

DDB_G0280291 EMBL EAL67372.1

Organism

Dictyostelium discoideum (Slime mold) [Reference proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	440 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EAL67372.1

Ontologies

Keywords
Molecular function	Hydrolase EMBL EAL67372.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	folic acid biosynthetic process Inferred from sequence or structural similarity. Source: dictyBase one-carbon metabolic process Inferred from Biological aspect of Ancestor. Source: RefGenome
Cellular_component	cytosol Inferred from Biological aspect of Ancestor. Source: RefGenome
Molecular_function	methenyltetrahydrofolate cyclohydrolase activity Inferred from sequence or structural similarity. Source: dictyBase methylenetetrahydrofolate dehydrogenase (NADP+) activity Inferred from sequence or structural similarity. Source: dictyBase nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q54VK0 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 91836EBD572496FD	FASTA	440	48,651
	10 20 30 40 50 60 MIFRGLKSLK NGFNTNNILI STNQSFKRFN ITPITTSSLF RNFTTNIEPK IESSTVNTTT 70 80 90 100 110 120 TNIPLSQSQT ENIPITPKKT FQPVKLDGKL LASHIVSSKK SIKADTEDFI KNSGVTPNLV 130 140 150 160 170 180 VIYVGDSKQI ESYIKAKRTG CEDVGFKFTL DRFSSDIKED QLIKKIKYHS EDPSVHGIIV 190 200 210 220 230 240 QLPLPDNLNK DAIIQSIDPK KDVDGLTSTN LGQIMISKKP LYIPCTPLGI LEILKAYKIK 250 260 270 280 290 300 VEGKNVVVLG RSNLVGRTIA TILSQKDLTN PSIMNGANVT IIHKYSKNHL GSIRQADLII 310 320 330 340 350 360 SATGVPGLIK KEDLKRGVIL IDVGISFKED STKKSGYKMV GDIDPEAYSR SIAYTPVPGG 370 380 390 400 410 420 VGPLTVACLL RNVLRSAILQ YRIQSARVGS ALNNKFTEKN NNNNNNVNNN NNNNNNNIND 430 440 DNNNNNIDNK NKNKNRKSRK

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." The Dictyostelium discoideum Sequencing Consortium Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAFI02000035 Genomic DNA. Translation: EAL67372.1.
RefSeq	XP_641355.1. XM_636263.1.
3D structure databases
ProteinModelPortal	Q54VK0.
ModBase	Search...
Protein-protein interaction databases
STRING	44689.DDB_0230117.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	DDB0230117; DDB0230117; DDB_G0280291.
GeneID	8622489.
KEGG	ddi:DDB_G0280291.
Organism-specific databases
dictyBase	DDB_G0280291.
Phylogenomic databases
eggNOG	COG0190.
InParanoid	Q54VK0.
OMA	HSEDPSV.
Family and domain databases
Gene3D	3.40.50.720. 1 hit.
HAMAP	MF_01576. THF_DHG_CYH.
InterPro	IPR016040. NAD(P)-bd_dom. IPR000672. THF_DH/CycHdrlase. IPR020630. THF_DH/CycHdrlase_cat_dom. IPR020631. THF_DH/CycHdrlase_NAD-bd_dom. [Graphical view]
Pfam	PF00763. THF_DHG_CYH. 1 hit. PF02882. THF_DHG_CYH_C. 1 hit. [Graphical view]
PRINTS	PR00085. THFDHDRGNASE.
ProtoNet	Search...

Entry information

Entry name

Q54VK0_DICDI

Accession

Primary (citable) accession number: Q54VK0

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	April 3, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)