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Protein

ABC transporter C family member 15

Gene

abcC15

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi575 – 582ATPPROSITE-ProRule annotation8
Nucleotide bindingi1227 – 1234ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DDI-114608. Platelet degranulation.
R-DDI-2142850. Hyaluronan biosynthesis and export.
R-DDI-382556. ABC-family proteins mediated transport.
R-DDI-5689880. Ub-specific processing proteases.
R-DDI-8856825. Cargo recognition for clathrin-mediated endocytosis.

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter C family member 15
Alternative name(s):
ABC transporter ABCC.15
Gene namesi
Name:abcC15
ORF Names:DDB_G0280459
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 3, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0280459. abcC15.

Subcellular locationi

  • Membrane PROSITE-ProRule annotation; Multi-pass membrane protein PROSITE-ProRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei8 – 28HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei129 – 149HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei165 – 185HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei238 – 258HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei261 – 281HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei349 – 369HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei373 – 393HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei873 – 893HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei919 – 939HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei985 – 1005HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei1017 – 1039HelicalPROSITE-ProRule annotationAdd BLAST23
Transmembranei1101 – 1121HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei1127 – 1147HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003638591 – 1436ABC transporter C family member 15Add BLAST1436

Proteomic databases

PaxDbiQ54VC1.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0216384.

Structurei

3D structure databases

ProteinModelPortaliQ54VC1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini128 – 412ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST285
Domaini543 – 766ABC transporter 1PROSITE-ProRule annotationAdd BLAST224
Domaini865 – 1155ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST291
Domaini1193 – 1426ABC transporter 2PROSITE-ProRule annotationAdd BLAST234

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi437 – 472Asn-richAdd BLAST36
Compositional biasi516 – 519Poly-Glu4
Compositional biasi539 – 542Poly-Gln4
Compositional biasi795 – 815Poly-AsnAdd BLAST21

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0054. Eukaryota.
COG1132. LUCA.
InParanoidiQ54VC1.
OMAiNDYWVSY.
PhylomeDBiQ54VC1.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q54VC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKKIKNIIN KIINFFSTIY ILCKIYLYYN IKNRYEAYNI LSVYGDDDFF
60 70 80 90 100
NKPCPEDSSN WKDKLTFKWV ERIIFVGFFR APLNLNDISD LPSSLKVENT
110 120 130 140 150
APLLKDIIFN DSTIPLIKHI YSKFLPRNYI ATGLFVFVSV FSFITPLILK
160 170 180 190 200
NFLSYVEKID EQKHIYIGII QCFLLFLSSF INMASQQYSY WFGFKTSLEV
210 220 230 240 250
KGALETIIFE KMTKLSNLSK KNYNIGSMLN LMSVDTDFFQ YFFCHYYIEI
260 270 280 290 300
FLFPIQILSL LGFLIYVIGI AGFVGFLVML ITIPLSSFLG TQISKNLSTS
310 320 330 340 350
MGYADTRISL TGELINGIKF LKQYAWEKMF CERIEEQRKL QLKYLYIRII
360 370 380 390 400
YWVLVQIVTQ ASSGLVLVST FTTYTLLGYE VSLEIAFTSI TILQNLRRPI
410 420 430 440 450
ESLPDCLHKF ISLIASAKRI ETFLQSSELQ NQPFIHNQSG LNDILIRNIN
460 470 480 490 500
FNWNEHNLKL KNNKNNQNNN QNKRSIILSS GEQFEITNDF TFDGIDIQDD
510 520 530 540 550
NYDYEKEYKI NYNNNEEEEN FMTDCLLKIK PLIKDRRLQQ QQADYQDLLS
560 570 580 590 600
INLPPPPSEN VDFKAPKGLL TIISGGVRSG KTSLASGLLG EICKAVDKSS
610 620 630 640 650
PDSVNSILST IQQPFLQSTS FRENILFGKP MNMERYIKVI EACCLAPDLL
660 670 680 690 700
AMGEGKDLTE IGERGINLSN GLKHRIQLAR ALYADSDCYI LDEILSSVDP
710 720 730 740 750
EIANYIFQHC IKGMMKGKTV ILVTHQIQFI SSADHVVVVD NGVLIQGTYL
760 770 780 790 800
ELLRMGIDFE MILKEKENRI EKQIVQLQED EDYYEEVEIL DFTMNNNNNN
810 820 830 840 850
NNNNNNNNSN FNGNNKLKRS SISLPKGISI ESIISKDFDQ TTIEKAKLFV
860 870 880 890 900
QEDRNKGDPG WIIYKKYIRM GSSISFFIFT CIIYLTSQII LLLSDYWLQS
910 920 930 940 950
WASHDRLNVS EPTDVHYLLI YLAYIGGFVF TLGVRYLLIA KITFGSAETL
960 970 980 990 1000
HRSLLKSIIR APLTFFEQNP VGRILNRFGK DISDIDILLL DCFSDVLYCG
1010 1020 1030 1040 1050
ACLVTSIGII IYISPYIAIP FVILIAINYI FQLFYNYSVL ELKRIQSISR
1060 1070 1080 1090 1100
SPVYSLLSEV YNGLTTIRSF GQQERFFNMM KDNININLRV FFYNFAVSRW
1110 1120 1130 1140 1150
IGIRVEFLSA IVVLMSALFS IFNDNPGLSA LGVTTALGIT FNLNWFMRQF
1160 1170 1180 1190 1200
GELESRINSV ERVQSYISIP KEKETNEDEF IQTGFIWPSR GEIEFKNVEI
1210 1220 1230 1240 1250
RYRPNSIATL RNFSMKINAQ ERIGIIGRSG SGKSTIGMSL FRMIECSSGS
1260 1270 1280 1290 1300
ILIDGDDISQ IDLKRLRSSI GIVPQDPFIF SGSIRLNLDP FDQFTDNEIW
1310 1320 1330 1340 1350
EALSKVKLKK MVSTMPMKLE SLVQGGDGLT IGNKQLLCLC RAILRNSKIV
1360 1370 1380 1390 1400
LFDEATNSID FQTTRLIKQT IEENFKDCTI LTIAHNIDTI LDSDKIAIID
1410 1420 1430
EGELIEFDTP LNLIKDSTSR FSKLIKLNNN QKNKLN
Length:1,436
Mass (Da):164,683
Last modified:May 24, 2005 - v1
Checksum:i9CC96CFA69AD9325
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000036 Genomic DNA. Translation: EAL67208.1.
RefSeqiXP_641188.1. XM_636096.1.

Genome annotation databases

EnsemblProtistsiEAL67208; EAL67208; DDB_G0280459.
GeneIDi8622569.
KEGGiddi:DDB_G0280459.

Entry informationi

Entry nameiABCCF_DICDI
AccessioniPrimary (citable) accession number: Q54VC1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: May 24, 2005
Last modified: June 7, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families