Reviewed, UniProtKB/Swiss-Prot Q54V86 (ABCCD_DICDI)

Names and origin

Protein names

Recommended name:
    ABC transporter C family member 13
Alternative name(s):
    ABC transporter ABCC.13

Gene names

Name:	abcC13
ORF Names:	DDB_G0280539

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	1350 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. [View classification] Contains 2 ABC transmembrane type-1 domains. Contains 2 ABC transporter domains.

Ontologies

Keywords
Biological process	Transport
Cellular component	Membrane
Domain	Repeat Transmembrane
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	transmembrane transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of substances Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1350	1350	ABC transporter C family member 13		PRO_0000363857
Regions
	Transmembrane	111 – 131	21	Potential
	Transmembrane	143 – 163	21	Potential
	Transmembrane	215 – 235	21	Potential
	Transmembrane	240 – 260	21	Potential
	Transmembrane	776 – 796	21	Potential
	Transmembrane	816 – 836	21	Potential
	Transmembrane	887 – 907	21	Potential
	Transmembrane	909 – 929	21	Potential
	Transmembrane	1003 – 1023	21	Potential
	Transmembrane	1029 – 1049	21	Potential
	Domain	107 – 390	284	ABC transmembrane type-1 1
	Domain	473 – 693	221	ABC transporter 1
	Domain	774 – 1061	288	ABC transmembrane type-1 2
	Domain	1103 – 1337	235	ABC transporter 2
	Nucleotide binding	505 – 512	8	ATP Potential
	Nucleotide binding	1137 – 1144	8	ATP Potential
	Compositional bias	447 – 454	8	Poly-Asn
	Compositional bias	700 – 708	9	Poly-Gln
Experimental info
	Sequence conflict	704	1	Q → H in AAL85716. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q54V86-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 88431B74E679D0E2	FASTA	1,350	154,170
	10 20 30 40 50 60 MFERINKIKK KIKEKLSYSI LKDEKIDYYN LPCPEESASF LSKLTFSWTQ RMLMTGYFRG 70 80 90 100 110 120 PIQMSDICDL PDDVKVQKTN PILDDIDFGN SKWPLLKFIY TNFVTKNKKS IFIVILCAIF 130 140 150 160 170 180 SILSPLCLKY FIKYIQLSKN EKTFLTGLGY CVLLFVGTFS YTLSQQFLYW FGMRTSLHVR 190 200 210 220 230 240 GALSQRIYEK MLKLSSSGGK KYSSGSIMNL ISTDIGLFAD FFWIGHLEII IFPIQITALL 250 260 270 280 290 300 ALLCWIVGWS GLVGFGVMII SLPINTFFGS KMSKNLMLSL GYSDTRCNLT SEFINGIRFL 310 320 330 340 350 360 KLYAWEKLFL DRIEEQRRLQ LKYLYRRVIF AIFEKMLSQT TNAVVLVSTF SVYSINNEIE 370 380 390 400 410 420 LSVAFTAITI FVNLRQPIMR LPEAIHNLLG LIPSAKRVES FLQLSEIQTQ PFINFNNKSI 430 440 450 460 470 480 NDDILIDNGT FNWNQDNDDY ITNNGDNNNN NNKNEIKKRL IEKSEEEYET TTTTTDDNNN 490 500 510 520 530 540 NNYESYLLNN INFKAPAGKL TIICGVVGSG KTSLVSGLIG EIYKVSGRVN TPNKISFTTQ 550 560 570 580 590 600 QSFLLSTSLR ENILFGNEMN LERYKKVIEA CCLAPDLLQL AAKDLTEIGE RGINLSGGQK 610 620 630 640 650 660 QRISLARALY ANSDCYILDE PLSAVDPEVA THLFNHCIQG MMNDKTRILV THQLQFIPSA 670 680 690 700 710 720 DHIVVVDNGK LVQGTYSELK SKGIDFESIM KTKKLNIDNQ QQQQQQQQHD ENEIIDENPM 730 740 750 760 770 780 KKSNSLIESN KLINIDEIIS DKHDSNLIEK AKLLVKEDKS EGAIGLHVYR EYFKHGSSTF 790 800 810 820 830 840 FFIATCVVYF FSQAIFQMTD FWLSTWSQHK LQGKSDSFYI FYYIIFIGLF IVTLVIRYFM 850 860 870 880 890 900 LAHVTFSASK NLHTSLLNSV GFASCQFFDT NPSGRILNRF SKDIAEIDLL LYDLFSDVLY 910 920 930 940 950 960 CGSTVVFAIC VMIYISPLIS LPFLVLIIVY NIIKNIYAVS SRDLKRYESI TRSPIFSLLQ 970 980 990 1000 1010 1020 ETFNGLVTIR SYQQQNRFIS MMQDHININL RLFYYSFSIH RWIGVRLEFI SALVVFLTAF 1030 1040 1050 1060 1070 1080 FSLFNSNAGF SVLSVTTAIG MCTYLNWAVR QFVELEVKMN SVERIESYIN TPKEGNRFTI 1090 1100 1110 1120 1130 1140 DNEEEGEENM INLNEKWPSK GEIEFRDVEI RYRPTSEPSL KNLSFKINSN DHIGIVGRTG 1150 1160 1170 1180 1190 1200 AGKSTVGISL FRMVECSKGS ILIDGIDISK IGLHDLRSSL GIVPQDPFIF SGTIRLNIDP 1210 1220 1230 1240 1250 1260 FNKYTDSEIW VALEKVKLKS TISSMPLKLE TMIEEGGDGL SFGQKQLLCL SRTILKNSKV 1270 1280 1290 1300 1310 1320 VLMDEATSGI DYVTGDLIKQ TLLENFNDCT MLTIAHRLDT IIDSTKIAVV DKGELIEYDT 1330 1340 1350 PINLINTKNS KFSKLVKYQT DFHKENEKNF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.
[2]	"Evolutionary analyses of ABC transporters of Dictyostelium discoideum." Anjard C., Loomis W.F. Eukaryot. Cell 1:643-652(2002) [PubMed: 12456012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 682-1350, NOMENCLATURE. Strain: AX4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AAFI02000037 Genomic DNA. Translation: EAL67071.1. AF474345 Genomic DNA. Translation: AAL85716.1.
RefSeq	XP_641045.1.
3D structure databases
HSSP	HSSP built from PDB template 2CBZ based on UniProtKB P33527.
ModBase	Search...
Genome annotation databases
GeneID	3392167.
GenomeReviews	Gene locus abcC13 in contig CM000152_GR.
KEGG	ddi:DDB_0215342.
Organism-specific databases
dictyBase	DDB_G0280539. abcC13.
Phylogenomic databases
HOGENOM	HBG758042.
InParanoid	Q54V86.
OMA	DIENIRE.
Family and domain databases
InterPro	IPR011527. ABC_TM_1. IPR001140. ABC_TM_transpt. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR017940. ABC_transporter_type1. IPR003593. ATPase_AAA+_core. [Graphical view]
Pfam	PF00664. ABC_membrane. 2 hits. PF00005. ABC_tran. 2 hits. [Graphical view]
SMART	SM00382. AAA. 2 hits. [Graphical view]
PROSITE	PS50929. ABC_TM1F. 2 hits. PS00211. ABC_TRANSPORTER_1. 2 hits. PS50893. ABC_TRANSPORTER_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABCCD_DICDI

Accession

Primary (citable) accession number: Q54V86
Secondary accession number(s): Q8T6G7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	May 24, 2005
Last modified:	December 15, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)