Reviewed, UniProtKB/Swiss-Prot Q54UP4 (TALDO_DICDI)

Names and origin

Protein names

Recommended name:
    Probable transaldolase
    EC=2.2.1.2

Gene names

Name:	tal
ORF Names:	DDB_G0280909

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	321 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity.
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the transaldolase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	transaldolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 321	321	Probable transaldolase		PRO_0000331219
Sites
	Active site	133	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q54UP4-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 9600C46B41D60CE7	FASTA	321	35,523
	10 20 30 40 50 60 MSNALEELKK YTTVVADTAD FDVLSKYGSQ DSTTNPSLVF QAASDPKYKS LIDDAIKYVN 70 80 90 100 110 120 AKSGLSEKEK LSLAIDKLFV NFGVEILKIV PGRVSTEVDA RLSYDIDANV KKGRELIALY 130 140 150 160 170 180 KEAGIDKERV LIKLASTWEG IEAAKILEKE GIHCNLTLLF SLIQAAACAE AQVTLISPFV 190 200 210 220 230 240 GRITDFYKSK QGVAGFEASK DPGVISVQQI YSYFKKHGYK TSVMGASFRN KEQTIELAGC 250 260 270 280 290 300 DLLTISPNLL EELKNADASL VTKKLDSTKL PSDIPNKLDV SHSNFLWELN DNEMAYFKTG 310 320 EGIRKFAEDL VKLENQIKKL L

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AAFI02000039 Genomic DNA. Translation: EAL66996.1.
RefSeq	XP_640977.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q54UP4.
Genome annotation databases
GeneID	3392067.
GenomeReviews	Gene locus tal in contig CM000152_GR.
KEGG	ddi:DDB_0231283.
Organism-specific databases
dictyBase	DDB_G0280909. tal.
Phylogenomic databases
OMA	EYKPQDA.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004730. Transaldolase_AB. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10683. Transaldolase. 1 hit. PTHR10683:SF3. Transaldolase_AB. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00874. talAB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TALDO_DICDI

Accession

Primary (citable) accession number: Q54UP4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 29, 2008
Last sequence update:	May 24, 2005
Last modified:	November 3, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)