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Reviewed, UniProtKB/Swiss-Prot Q54U44 (ABCCC_DICDI)

Last modified December 15, 2009. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    ABC transporter C family member 12
Alternative name(s):
    ABC transporter ABCC.12
Gene names
Name: abcC12
ORF Names: DDB_G0280973
OrganismDictyostelium discoideum (Slime mold) [Complete proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length1323 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Ontologies

Keywords
   Biological processTransport
   Cellular componentMembrane
   DomainRepeat
Transmembrane
   LigandATP-binding
Nucleotide-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtransmembrane transport

Inferred from electronic annotation. Source: InterPro

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ATPase activity, coupled to transmembrane movement of substances

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 13231323ABC transporter C family member 12
PRO_0000363856

Regions

Transmembrane111 – 13121 Potential
Transmembrane152 – 17221 Potential
Transmembrane227 – 24721 Potential
Transmembrane252 – 27221 Potential
Transmembrane338 – 35821 Potential
Transmembrane375 – 39521 Potential
Transmembrane712 – 73221 Potential
Transmembrane772 – 79221 Potential
Transmembrane840 – 86021 Potential
Transmembrane862 – 88221 Potential
Transmembrane952 – 97221 Potential
Domain110 – 396287ABC transmembrane type-1 1
Domain428 – 652225ABC transporter 1
Domain720 – 1010291ABC transmembrane type-1 2
Domain1047 – 1281235ABC transporter 2
Nucleotide binding464 – 4718ATP Potential
Nucleotide binding1081 – 10888ATP Potential
Compositional bias662 – 6698Poly-Asp

Experimental info

Sequence conflict10 – 1910DNLETKGGKE → EIWKLREER in AAL85715. Ref.2
Sequence conflict8291R → C in AAL85715. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q54U44-1 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 338966DE25C8F404

FASTA1,323148,126
        10         20         30         40         50         60 
MEDIELNSVD NLETKGGKEI KKKEKKIGYG GKKSPEENSN FLSNLTFSWA DGFVIHCFRN 

        70         80         90        100        110        120 
VLQLSHLWDL ASYDKSEYLA KKIAKSWEIE IQKPKPSYLR AGFRAFGKLH CISLFFYSIY 

       130        140        150        160        170        180 
VGSQFVGPEI LSRMVTFVVE SKLGTSTEDP NMGYYYALIM FGTAMIGSFC NYQANRVTVR 

       190        200        210        220        230        240 
TGDRLRSIIV LDVYKKAIKL SNSARSNTSP GQIVNLISND AQRMIEVFGI LNNGLFALPQ 

       250        260        270        280        290        300 
IIICLALLYE KIGWPTFVGL GLMLAAIPFN GLAAKKLTET RRILIGHTDG RVKVTSEILQ 

       310        320        330        340        350        360 
AMKIIKLYAW EDSFAKKVLD RRNNEIKLLF SFTRYRTILI AMIGAIPTAA SILVFSTYYG 

       370        380        390        400        410        420 
YNGSLDAGKI FSALSYLNLL KIPLGFLPIL IALGIQMQIA SKRVTDFLLL PEMKEVQQID 

       430        440        450        460        470        480 
NPSLPNGVYM KNSTTTWNKE KEDSFGLKNI NFEAKGQSLT MVVGSVGSGK STLVQAMLGE 

       490        500        510        520        530        540 
LETIDGEIGI KGSIAYVPQQ AWIINATLKE NIIFGKELDE ERYQKVLEVC ALKRDIELFP 

       550        560        570        580        590        600 
QGDSVEIGER GINLSGGQKQ RVSIARAVYS DADVYILDDP LSAVDSHVGK HLFHKCFKGI 

       610        620        630        640        650        660 
LSSKTVILVA NQINYLPFAD NTVVLKSGEI VERGTYYELI NAKLEFASLL QEYGVDENTK 

       670        680        690        700        710        720 
GDDSDDDDDK KDDDKKEEKV EKPKQSDKDG TLISEEEAEQ GAVAGKVYWK YVTAGGGLLF 

       730        740        750        760        770        780 
LFAMILFLLE TGSKTFTDWW LSHWQTESSE RMESILLGEE PTGLTDDQNL GIYIGVGMAS 

       790        800        810        820        830        840 
IIVTVVRTFS FFEYAVRAAH SIHHELFNAL LKKPMSFFDQ TPLGRIINRF TRDLDIIDNL 

       850        860        870        880        890        900 
IATSIAQFFT LMLSVLATLI LISIIVPWLL IPLAPICILF FILQYFYRYT SRGLQRIEAI 

       910        920        930        940        950        960 
TRSPIFNHFS ETLNGVVSIR AYKKQQENIL KNQKRLDDNN NCYLTLQAMN RWLGLRLDFL 

       970        980        990       1000       1010       1020 
GNLIVFFSCI FITLKKDTIS PSDVGLVLSY ALSITSNLNQ GVLQAADTET KMNSVERISQ 

      1030       1040       1050       1060       1070       1080 
YIRGAVEAPQ IIDDCRPSPD WPINGSIKFD NLVMRYREGL DPVLKGITCE IKAKEKIGIV 

      1090       1100       1110       1120       1130       1140 
GRTGAGKSSI VLALFRLIEA SEGSISIDGE NIAKFGLKDL RRNLAIIPQD PVLFSGTLRE 

      1150       1160       1170       1180       1190       1200 
NLDPFNECPD HELWSILDDI QLSKVFKSTE EGLNSKVTEN GENFSVGQRQ LIVLARALLR 

      1210       1220       1230       1240       1250       1260 
KPKILVLDEA TASVDGQSDS LIQATIRNKF SNCTILTIAH RLNTIMDSDK IMVLDAGKIS 

      1270       1280       1290       1300       1310       1320 
EFDEPWTLLQ NQNGLLTWLV NETGPQNAIY LRKLAEAKKS GLNINEITQI DQQNDNLNTP 


PRL 

« Hide

References

« Hide 'large scale' references
[1]"The genome of the social amoeba Dictyostelium discoideum."
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. expand/collapse author list , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
Nature 435:43-57(2005) [PubMed: 15875012] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AX4.
[2]"Evolutionary analyses of ABC transporters of Dictyostelium discoideum."
Anjard C., Loomis W.F.
Eukaryot. Cell 1:643-652(2002) [PubMed: 12456012] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-1265, NOMENCLATURE.
Strain: AX4.

Cross-references

Sequence databases

AAFI02000040 Genomic DNA. Translation: EAL66783.1.
AF474344 Genomic DNA. Translation: AAL85715.1.
RefSeqXP_640932.1.

3D structure databases

HSSPHSSP built from PDB template 2CBZ based on UniProtKB P33527.
ModBaseSearch...

Genome annotation databases

GeneID3391868.
GenomeReviewsGene locus abcC12 in contig CM000152_GR.
KEGGddi:DDB_0214809.

Organism-specific databases

dictyBaseDDB_G0280973. abcC12.

Phylogenomic databases

HOGENOMHBG758042.
InParanoidQ54U44.
OMACADERIN.

Family and domain databases

InterProIPR011527. ABC_TM_1.
IPR001140. ABC_TM_transpt.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR017940. ABC_transporter_type1.
IPR003593. ATPase_AAA+_core.
[Graphical view]
PfamPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTSM00382. AAA. 2 hits.
[Graphical view]
PROSITEPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameABCCC_DICDI
AccessionPrimary (citable) accession number: Q54U44
Secondary accession number(s): Q8T6G8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: May 24, 2005
Last modified: December 15, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents