Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q54TV2 (ABCG5_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified September 21, 2011. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ABC transporter G family member 5
Alternative name(s):
ABC transporter ABCG.5
Gene names
Name:abcG5
ORF Names:DDB_G0281391
OrganismDictyostelium discoideum (Slime mold)
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length1509 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily. [View classification]

Contains 2 ABC transmembrane type-2 domains.

Contains 2 ABC transporter domains.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 15091509ABC transporter G family member 5
PRO_0000330363

Regions

Transmembrane477 – 49721Helical; Potential
Transmembrane512 – 53221Helical; Potential
Transmembrane557 – 57721Helical; Potential
Transmembrane583 – 60321Helical; Potential
Transmembrane616 – 63621Helical; Potential
Transmembrane643 – 66321Helical; Potential
Transmembrane725 – 74521Helical; Potential
Transmembrane1236 – 125621Helical; Potential
Transmembrane1271 – 129121Helical; Potential
Transmembrane1320 – 134021Helical; Potential
Transmembrane1352 – 137221Helical; Potential
Transmembrane1379 – 139921Helical; Potential
Transmembrane1481 – 150121Helical; Potential
Domain129 – 376248ABC transporter 1
Domain472 – 748277ABC transmembrane type-2 1
Domain888 – 1141254ABC transporter 2
Domain1231 – 1504274ABC transmembrane type-2 2
Nucleotide binding168 – 1758ATP 1 Potential
Nucleotide binding935 – 9428ATP 2 Potential
Compositional bias21 – 6646Asn-rich
Compositional bias760 – 7678Poly-Lys
Compositional bias818 – 8247Poly-Asn

Experimental info

Sequence conflict1371T → P in AAL91490. Ref.1
Sequence conflict5101F → L in AAL91490. Ref.1
Sequence conflict11601E → Q in AAL91490. Ref.1
Sequence conflict1172 – 11732EH → VP in AAL91490. Ref.1
Sequence conflict11841N → D in AAL91490. Ref.1
Sequence conflict12041V → I in AAL91490. Ref.1
Sequence conflict15041V → I in AAL91490. Ref.1
Sequence conflict15071L → F in AAL91490. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q54TV2 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: B6AA767896850909

FASTA1,509170,937
        10         20         30         40         50         60 
MVKQDPRDKS SYSPNLSIPI NNQEEPTLNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNK 

        70         80         90        100        110        120 
NNNNNNIKHK DEENDFEDSI YQIAKEHEGE EDDEYFPIPL DELMPNHEND ELTKKIKQTR 

       130        140        150        160        170        180 
PEDKTGLYVY CRNATYTVKH RENKKVKIKL LDDVSFFLRP KQMTLILGTP GCGKSTIFQM 

       190        200        210        220        230        240 
LAGQLKDKHF EGELLFNGHP INHKNHHRDI SYVTQDDIHV PTLTVKETFR FALDCLGKKE 

       250        260        270        280        290        300 
LTREEKQVSV DNCMKLLGLK HAENTLVGDN FIRGISGGQK KRVTIGVGVI KGSNLLLMDE 

       310        320        330        340        350        360 
PTSGLDSSTS FEILSDVKKF VTYGYSPALI TLLQPSVQLT SLFDNLMIMS KGKICYFGPM 

       370        380        390        400        410        420 
NRALGYFKKL GFACPSHNNP AEFFQEVVDA PERYSFIHPP KCKTSDDFVK AYRESDIYLE 

       430        440        450        460        470        480 
LMEKMDANKD GIVDDNKPKV LVDSTAKELG MYPHGIGYQT KICLKRGFIM ISRNYYNFAT 

       490        500        510        520        530        540 
RVFKGIFFGL LLGTLYWRIG HNQSGGMERF GLLFFIMTTI IFSSFAAVNS FFGERKVFYS 

       550        560        570        580        590        600 
QKALHYYKTG AYFISSIICD IPAGLIEVAF FGPIVYWLAN LRPVFIRFVY FMILLFITDN 

       610        620        630        640        650        660 
LSLSFAKMCA AISPTIEIAN VTASVILSIW LLFSGFTAPK NDIGGWWIWL YYISPYTWIF 

       670        680        690        700        710        720 
QGLSINEFTY QAYGCKDSEL IPPRTPQNLL PYPEGFGGNQ VCQYTSGEQI MDAFGINNPD 

       730        740        750        760        770        780 
YFKWIVYAIL GAYIVFFYSV CFFALKYLNF EDKKSKLAVK KLKKKKKVIV CKEDEEPNCK 

       790        800        810        820        830        840 
VTTEALERVS DDNDDNADIS NYDDDTVIDM KSPLTSPNYN NNNNLSGSGN NIKRRKVKTP 

       850        860        870        880        890        900 
STLSPMVNSP LTNLSPMVNT PSKNGNHSKQ KPISTSQKDI SSETGSYLQF KKLCYAVDVK 

       910        920        930        940        950        960 
ADDPDNPKKK KSQRLQLLTD IDGYVKPGQM LALMGPSGAG KSTLLDVLAQ RKTGGHITGE 

       970        980        990       1000       1010       1020 
ILINGKPPSE FTNRIRAYVE QMDVLPPTQT VREAIAFSAR CRLPPEVTKE EREIFVDKIV 

      1030       1040       1050       1060       1070       1080 
EVLSLSSIKD LKIGVLGNGL SVSQRKRVNI GVELASNPEI LFLDEPTSGL DSGDAFKVID 

      1090       1100       1110       1120       1130       1140 
VVNKIAKVMN RTVICTVHQP SAAIFEFFDQ LLLLKKGGET IYFGPLGNQS SVILDYCDKL 

      1150       1160       1170       1180       1190       1200 
GMHIKPHINP ADFVMTLADE GKMVEGPNGE QEHLDAKKAY FESNICKKEY EIMEGQLIPD 

      1210       1220       1230       1240       1250       1260 
DFVVKTYDSR FASSWMTQFR ALCMRSWLSR LRRPAIFVSN CLRSILLAVL LGTLFVRMDY 

      1270       1280       1290       1300       1310       1320 
EQKDARSRVS LLFFSFLFAG MVAIGNIPTT VLERGVFYRE VTAGFYHSTA YMISYVLTSY 

      1330       1340       1350       1360       1370       1380 
PFILSTGILY IIPTFWIAGL DSGRHSSKFW YCLFIFIITY IMYDAFALCL AVCLPNEVMA 

      1390       1400       1410       1420       1430       1440 
STICGIGLSL ATLFGGFVIA RPNYPSAYYW CHYLDWLRYP LEASCTNEFT GLTFVCTNNK 

      1450       1460       1470       1480       1490       1500 
GAVPIPIIEN GVQIAIKYYC PITNGDDFML TYGFHKFMRY IDIAAIFGYI FIFVGLSFWG 


FKKVRWLNR

« Hide

References

« Hide 'large scale' references
[1]"Evolutionary analyses of ABC transporters of Dictyostelium discoideum."
Anjard C., Loomis W.F.
Eukaryot. Cell 1:643-652(2002) [PubMed: 12456012] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], NOMENCLATURE.
Strain: AX4.
[2]"The genome of the social amoeba Dictyostelium discoideum."
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. expand/collapse author list , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
Nature 435:43-57(2005) [PubMed: 15875012] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AX4.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF482384 Genomic DNA. Translation: AAL91490.1.
AAFI02000041 Genomic DNA. Translation: EAL66677.1.
RefSeqXP_640709.1. XM_635617.1.

3D structure databases

ProteinModelPortalQ54TV2.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0215344; DDB0215344; DDB_G0281391.
GeneID8623096.
GenomeReviewsGene locus abcG5 in contig CM000152_GR.
KEGGddi:DDB_G0281391.

Organism-specific databases

dictyBaseDDB_G0281391. abcG5.

Phylogenomic databases

eggNOGKOG0065.
GeneTreeEPrGT00050000001450.
HOGENOMHBG081041.
OMARLFKQYI.
PhylomeDBQ54TV2.
ProtClustDBCLSZ2430551.

Family and domain databases

InterProIPR013525. ABC_2_trans.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR011989. ARM-like.
IPR003593. ATPase_AAA+_core.
[Graphical view]
Gene3DG3DSA:1.25.10.10. ARM-like. 1 hit.
PfamPF01061. ABC2_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTSM00382. AAA. 2 hits.
[Graphical view]
PROSITEPS51012. ABC_TM2. False negative.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameABCG5_DICDI
AccessionPrimary (citable) accession number: Q54TV2
Secondary accession number(s): Q8T688
Entry history
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: May 24, 2005
Last modified: September 21, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents