Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q54T01

- Y2105_DICDI

UniProt

Q54T01 - Y2105_DICDI

Protein

Probable protein phosphatase DDB_G0282105

Gene

DDB_G0282105

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi722 – 7221Manganese 1By similarity
    Metal bindingi722 – 7221Manganese 2By similarity
    Metal bindingi723 – 7231Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi905 – 9051Manganese 2By similarity
    Metal bindingi949 – 9491Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: InterPro

    GO - Biological processi

    1. protein dephosphorylation Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase DDB_G0282105 (EC:3.1.3.16)
    Gene namesi
    ORF Names:DDB_G0282105
    OrganismiDictyostelium discoideum (Slime mold)
    Taxonomic identifieri44689 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
    ProteomesiUP000002195: Chromosome 3, UP000002195: Unassembled WGS sequence

    Organism-specific databases

    dictyBaseiDDB_G0282105.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 958958Probable protein phosphatase DDB_G0282105PRO_0000369246Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi44689.DDBDRAFT_0205134.

    Structurei

    3D structure databases

    ProteinModelPortaliQ54T01.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei2 – 2221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei26 – 4621HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini619 – 958340PP2C-likeAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili142 – 330189Sequence AnalysisAdd
    BLAST
    Coiled coili613 – 66654Sequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi57 – 604Poly-Ser
    Compositional biasi65 – 7410Poly-Thr
    Compositional biasi82 – 854Poly-Gln
    Compositional biasi89 – 924Poly-Gln
    Compositional biasi95 – 1006Poly-Gln
    Compositional biasi336 – 3394Poly-Ser
    Compositional biasi411 – 4166Poly-Ser
    Compositional biasi456 – 47318Poly-ThrAdd
    BLAST
    Compositional biasi486 – 4894Poly-Ser
    Compositional biasi504 – 51512Poly-SerAdd
    BLAST

    Sequence similaritiesi

    In the C-terminal section; belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Keywords - Domaini

    Coiled coil, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0631.
    InParanoidiQ54T01.
    OMAiQNIGMIS.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.
    PROSITEiPS01032. PP2C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q54T01-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVLMMDIKIM SAFSILFLSL MVSNEFLEFL ANTVYAAILF IIILFFYQNR    50
    QHFFTTSSSS KDSLTSTTTT TTTTSITSSL IQQQQEKEQQ QQLEQQQQQQ 100
    SIKLITKEIT IENDSEKNTS TTTSIITKEQ SPGSVRLIQN YSASQQSELT 150
    NTTIKQLQQK NQELQEQINN QIEKSRKDQL KYFNSNNKSQ SEIKEQIEKI 200
    IKLTEKNDDL LNSIVILNST IDGNRIKMQE ITKDRDSIYS SEQKLLSRLT 250
    AFEKKEKEYQ DNEKQLQKKL SDQKDQYSTL KKEFDEKVKK SNKLENSIQS 300
    LESQIQKLLQ KQEKEKQKLE KDKERERSSS FSSDISSSST TSTTASTFLS 350
    SSPSKSIPIP IPIKTSNAIS DLKRNNSNDS VNGLIGNGNS SVSPPSSSYL 400
    RESSDDSDNQ SSSSPSEPKF KSLFNKVKSE SSKIVNKAQK GINKHLGSDF 450
    FTPANTTTST TTTTSTTSTS TTTPITSASA TAAAISSSSI ITSPTTNTTN 500
    DILSSSSSSS SSSSSLLTTN AILSPPVGNE QQMEVINDKT EVNQSPVKPL 550
    IFFDDLGNDK LLDSTTEEQI QSKMTISPRD KDRILIDKEQ SLSDLFINSK 600
    ENISNISVSN LDNFLKTNNN NNKNNIEESN NNNNNNNNNN NNNNNNNNNN 650
    NNNNKNDNKE VNSKLEFSIK DEENKIGLRR AKKKLSPGCS TMMEDVSIAI 700
    YPFLKEKKLS NCSNIGLFGV FDGHAGRGAA DSASKLFPKE IEKLLESGNY 750
    SLTEQDDGGD NNHNQSKLLN DLFSNVDNKM KDHEYEGCTA TLALIWSDGE 800
    EQQQQQQRYL QVGNVGDSSA FLCRGNESIE LTFDHKANDP SEKQRIKDQG 850
    IPVSDNQTRI NGVAVSRSLG NHFIKEQNIG MISTPHISNR YLLTPQDKFV 900
    IIASDGLWDV INGKDAIEKV SSLYDQGATA DSMASCLLET AIQSSLCKDN 950
    VTVIIVKL 958
    Length:958
    Mass (Da):106,617
    Last modified:May 24, 2005 - v1
    Checksum:iD5B23D9AB572162B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000045 Genomic DNA. Translation: EAL66378.1.
    RefSeqiXP_640354.1. XM_635262.1.

    Genome annotation databases

    EnsemblProtistsiDDB0235260; DDB0235260; DDB_G0282105.
    GeneIDi8623409.
    KEGGiddi:DDB_G0282105.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000045 Genomic DNA. Translation: EAL66378.1 .
    RefSeqi XP_640354.1. XM_635262.1.

    3D structure databases

    ProteinModelPortali Q54T01.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 44689.DDBDRAFT_0205134.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi DDB0235260 ; DDB0235260 ; DDB_G0282105 .
    GeneIDi 8623409.
    KEGGi ddi:DDB_G0282105.

    Organism-specific databases

    dictyBasei DDB_G0282105.

    Phylogenomic databases

    eggNOGi COG0631.
    InParanoidi Q54T01.
    OMAi QNIGMIS.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    PROSITEi PS01032. PP2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the social amoeba Dictyostelium discoideum."
      Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
      , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
      Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX4.

    Entry informationi

    Entry nameiY2105_DICDI
    AccessioniPrimary (citable) accession number: Q54T01
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Dictyostelium discoideum
      Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3