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Q54T01 (Y2105_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase DDB_G0282105

EC=3.1.3.16
Gene names
ORF Names:DDB_G0282105
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length958 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

In the C-terminal section; belongs to the PP2C family.

Contains 1 PP2C-like domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 958958Probable protein phosphatase DDB_G0282105
PRO_0000369246

Regions

Transmembrane2 – 2221Helical; Potential
Transmembrane26 – 4621Helical; Potential
Domain619 – 958340PP2C-like
Coiled coil142 – 330189 Potential
Coiled coil613 – 66654 Potential
Compositional bias57 – 604Poly-Ser
Compositional bias65 – 7410Poly-Thr
Compositional bias82 – 854Poly-Gln
Compositional bias89 – 924Poly-Gln
Compositional bias95 – 1006Poly-Gln
Compositional bias336 – 3394Poly-Ser
Compositional bias411 – 4166Poly-Ser
Compositional bias456 – 47318Poly-Thr
Compositional bias486 – 4894Poly-Ser
Compositional bias504 – 51512Poly-Ser

Sites

Metal binding7221Manganese 1 By similarity
Metal binding7221Manganese 2 By similarity
Metal binding7231Manganese 1; via carbonyl oxygen By similarity
Metal binding9051Manganese 2 By similarity
Metal binding9491Manganese 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q54T01 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: D5B23D9AB572162B

FASTA958106,617
        10         20         30         40         50         60 
MVLMMDIKIM SAFSILFLSL MVSNEFLEFL ANTVYAAILF IIILFFYQNR QHFFTTSSSS 

        70         80         90        100        110        120 
KDSLTSTTTT TTTTSITSSL IQQQQEKEQQ QQLEQQQQQQ SIKLITKEIT IENDSEKNTS 

       130        140        150        160        170        180 
TTTSIITKEQ SPGSVRLIQN YSASQQSELT NTTIKQLQQK NQELQEQINN QIEKSRKDQL 

       190        200        210        220        230        240 
KYFNSNNKSQ SEIKEQIEKI IKLTEKNDDL LNSIVILNST IDGNRIKMQE ITKDRDSIYS 

       250        260        270        280        290        300 
SEQKLLSRLT AFEKKEKEYQ DNEKQLQKKL SDQKDQYSTL KKEFDEKVKK SNKLENSIQS 

       310        320        330        340        350        360 
LESQIQKLLQ KQEKEKQKLE KDKERERSSS FSSDISSSST TSTTASTFLS SSPSKSIPIP 

       370        380        390        400        410        420 
IPIKTSNAIS DLKRNNSNDS VNGLIGNGNS SVSPPSSSYL RESSDDSDNQ SSSSPSEPKF 

       430        440        450        460        470        480 
KSLFNKVKSE SSKIVNKAQK GINKHLGSDF FTPANTTTST TTTTSTTSTS TTTPITSASA 

       490        500        510        520        530        540 
TAAAISSSSI ITSPTTNTTN DILSSSSSSS SSSSSLLTTN AILSPPVGNE QQMEVINDKT 

       550        560        570        580        590        600 
EVNQSPVKPL IFFDDLGNDK LLDSTTEEQI QSKMTISPRD KDRILIDKEQ SLSDLFINSK 

       610        620        630        640        650        660 
ENISNISVSN LDNFLKTNNN NNKNNIEESN NNNNNNNNNN NNNNNNNNNN NNNNKNDNKE 

       670        680        690        700        710        720 
VNSKLEFSIK DEENKIGLRR AKKKLSPGCS TMMEDVSIAI YPFLKEKKLS NCSNIGLFGV 

       730        740        750        760        770        780 
FDGHAGRGAA DSASKLFPKE IEKLLESGNY SLTEQDDGGD NNHNQSKLLN DLFSNVDNKM 

       790        800        810        820        830        840 
KDHEYEGCTA TLALIWSDGE EQQQQQQRYL QVGNVGDSSA FLCRGNESIE LTFDHKANDP 

       850        860        870        880        890        900 
SEKQRIKDQG IPVSDNQTRI NGVAVSRSLG NHFIKEQNIG MISTPHISNR YLLTPQDKFV 

       910        920        930        940        950 
IIASDGLWDV INGKDAIEKV SSLYDQGATA DSMASCLLET AIQSSLCKDN VTVIIVKL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000045 Genomic DNA. Translation: EAL66378.1.

3D structure databases

ProteinModelPortalQ54T01.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDBDRAFT_0205134.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0235260; DDB0235260; DDB_G0282105.
KEGGddi:DDB_G0282105.

Organism-specific databases

dictyBaseDDB_G0282105.

Phylogenomic databases

eggNOGCOG0631.
InParanoidQ54T01.
OMAQNIGMIS.

Family and domain databases

Gene3D3.60.40.10. 1 hit.
InterProIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 1 hit.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 1 hit.
PROSITEPS01032. PP2C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY2105_DICDI
AccessionPrimary (citable) accession number: Q54T01
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 24, 2005
Last modified: April 16, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase