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Q54SV3 (ALN1_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable allantoinase 1

EC=3.5.2.5
Gene names
Name:allB1
ORF Names:DDB_G0282199
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length649 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-allantoin + H2O = allantoate.

Cofactor

Binds 2 zinc ions per subunit By similarity.

Pathway

Nitrogen metabolism; (S)-allantoin degradation; allantoate from (S)-allantoin: step 1/1.

Subunit structure

Homotetramer By similarity.

Post-translational modification

Carbamylation allows a single lysine to coordinate two zinc ions By similarity.

Sequence similarities

Belongs to the DHOase family. Allantoinase subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 649649Probable allantoinase 1
PRO_0000330750

Sites

Metal binding661Zinc 1 By similarity
Metal binding681Zinc 1 By similarity
Metal binding1541Zinc 1; via carbamate group By similarity
Metal binding1541Zinc 2; via carbamate group By similarity
Metal binding1971Zinc 2 By similarity
Metal binding2551Zinc 2 By similarity
Metal binding3291Zinc 1 By similarity

Amino acid modifications

Modified residue1541N6-carboxylysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q54SV3 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 1E4C7067D47B28F2

FASTA64972,476
        10         20         30         40         50         60 
MNSENIIKVI KGKKVVINGE IKPASILIKN GIIIDIKDYS SEIKEEHEVL IEEEKLVIMG 

        70         80         90        100        110        120 
GLVDSHVHIN EPGRTEWEGF LSATSAAASG GVTTIIDMPL NSSPVTTTFE NLQTKIESMP 

       130        140        150        160        170        180 
GKLRVDVGLL GGIIPGNSSE ISRMVLEGGV VGFKSFLVHS GIDEFPHVKE DDIQEAMNVM 

       190        200        210        220        230        240 
KKLKDEQGGR DVVMMFHAEI EEPIKEATER LQRENADPKL YDTFLKSRPR VSENIAIDKV 

       250        260        270        280        290        300 
IELTKKNMIK THIVHLSSSD AIEAIHEAVH NDGVPITAET TYHYLYFESE QVPYGNTLYK 

       310        320        330        340        350        360 
CCPPVRESEN KDLLWKAVTN GTINIIVSDH SPCTLDLKLI EQGDFMKAWG GISSLQLGLP 

       370        380        390        400        410        420 
IIWTEASKRG VPLAKLSEYM SDAPSRLVGL NDRKGSIKIG RDADFVIWDP EESFTVDQGL 

       430        440        450        460        470        480 
LMVKNKNSPY HGEKLLGVVH HTILRGNKIF SKGDQTISKI IGKRLIQTKI HTNPIYPSPT 

       490        500        510        520        530        540 
LPTIELLNSL TEQKTFFDCI HLLFEAAPPL ANALFSKRPF SSYQQLIDQA YSIIQSLNES 

       550        560        570        580        590        600 
DKIQVINAHP RIGVSASQVK NSSSISYREQ SCDKDSSIDQ SILENLTQLN QQYESKFGFK 

       610        620        630        640 
FVVFVNGRPK NEIIPILQNR LNNNDKQKEL NLGLSEMIEI SKSRLLKLL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000046 Genomic DNA. Translation: EAL66305.1.

3D structure databases

ProteinModelPortalQ54SV3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDB_0231352.

Proteomic databases

PRIDEQ54SV3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0231352; DDB0231352; DDB_G0282199.
KEGGddi:DDB_G0282199.

Organism-specific databases

dictyBaseDDB_G0282199. allB1.

Phylogenomic databases

eggNOGCOG0044.
KOK01466.
OMAPIIWTEA.
PhylomeDBQ54SV3.
ProtClustDBCLSZ2430485.

Enzyme and pathway databases

UniPathwayUPA00395; UER00653.

Family and domain databases

Gene3D1.10.3330.10. 1 hit.
2.30.40.10. 1 hit.
InterProIPR017593. Allantoinase.
IPR006680. Amidohydro_1.
IPR002195. Dihydroorotase_CS.
IPR018228. DNase_TatD-rel_CS.
IPR011059. Metal-dep_hydrolase_composite.
IPR018020. OHCU_decarboxylase.
[Graphical view]
PfamPF01979. Amidohydro_1. 1 hit.
PF09349. OHCU_decarbox. 1 hit.
[Graphical view]
SUPFAMSSF51338. SSF51338. 2 hits.
TIGRFAMsTIGR03178. allantoinase. 1 hit.
PROSITEPS00482. DIHYDROOROTASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROQ54SV3.

Entry information

Entry nameALN1_DICDI
AccessionPrimary (citable) accession number: Q54SV3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: May 24, 2005
Last modified: April 16, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase