Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q54RB2

- CDK11_DICDI

UniProt

Q54RB2 - CDK11_DICDI

Protein

Cyclin-dependent kinase 11

Gene

cdk11

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei81 – 811ATPPROSITE-ProRule annotation
    Active sitei176 – 1761Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi58 – 669ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: dictyBase
    2. cyclin-dependent protein serine/threonine kinase activity Source: UniProtKB-EC
    3. protein serine/threonine kinase activity Source: dictyBase

    GO - Biological processi

    1. protein phosphorylation Source: dictyBase

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cyclin-dependent kinase 11 (EC:2.7.11.22)
    Alternative name(s):
    Cell division cycle protein kinase 11
    Cell division protein kinase 11
    PITSVRE serine/threonine protein-kinase cdk11
    Gene namesi
    Name:cdk11
    ORF Names:DDB_G0283279
    OrganismiDictyostelium discoideum (Slime mold)
    Taxonomic identifieri44689 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
    ProteomesiUP000002195: Chromosome 4, UP000002195: Unassembled WGS sequence

    Organism-specific databases

    dictyBaseiDDB_G0283279. cdk11.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 358358Cyclin-dependent kinase 11PRO_0000353101Add
    BLAST

    Proteomic databases

    PRIDEiQ54RB2.

    Interactioni

    Protein-protein interaction databases

    STRINGi44689.DDB_0216376.

    Structurei

    3D structure databases

    ProteinModelPortaliQ54RB2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini52 – 336285Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    KOiK08818.
    OMAiKKLYTIN.
    PhylomeDBiQ54RB2.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q54RB2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSNIQENENK ETCNIKENEN KEILKENFKN KEKQYFSSLR SPYSACRSVD    50
    CFKKLYTINE GAFGVVYCAQ DKETEEIVAL KKIKMERERE GIPITSVREI 100
    KVLMELKHDN IVQIKEIVLG KNINSIFMAM EFIDHDLRGL MEVIKKPFLP 150
    SEIKTLIQQL LNGVSYMHDN WVIHRDLKTA NLLYTNKGVL KIADFGLARE 200
    YGSPLKPLSK GVVTLWYRAP ELLLDTEIYT PAIDIWSVGC IFAEIISKEV 250
    LLQGSSEIDQ MDKIFKLFGT PTEKSWPAFF KLPLAKYFNL TDQPYNNLKS 300
    KFPHITDNAF DLLNKLLELN PEARISASDA LKHPYFFENP QPRDPLLMPT 350
    WPSSHKKT 358
    Length:358
    Mass (Da):41,358
    Last modified:May 24, 2005 - v1
    Checksum:i8458157B95470084
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000052 Genomic DNA. Translation: EAL65780.1.
    RefSeqiXP_639135.1. XM_634043.1.

    Genome annotation databases

    EnsemblProtistsiDDB0216376; DDB0216376; DDB_G0283279.
    GeneIDi8624005.
    KEGGiddi:DDB_G0283279.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000052 Genomic DNA. Translation: EAL65780.1 .
    RefSeqi XP_639135.1. XM_634043.1.

    3D structure databases

    ProteinModelPortali Q54RB2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 44689.DDB_0216376.

    Proteomic databases

    PRIDEi Q54RB2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi DDB0216376 ; DDB0216376 ; DDB_G0283279 .
    GeneIDi 8624005.
    KEGGi ddi:DDB_G0283279.

    Organism-specific databases

    dictyBasei DDB_G0283279. cdk11.

    Phylogenomic databases

    eggNOGi COG0515.
    KOi K08818.
    OMAi KKLYTIN.
    PhylomeDBi Q54RB2.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the social amoeba Dictyostelium discoideum."
      Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
      , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
      Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX4.

    Entry informationi

    Entry nameiCDK11_DICDI
    AccessioniPrimary (citable) accession number: Q54RB2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 25, 2008
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Dictyostelium discoideum
      Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3