Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q54RB2 (CDK11_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cyclin-dependent kinase 11

EC=2.7.11.22
Alternative name(s):
Cell division cycle protein kinase 11
Cell division protein kinase 11
PITSVRE serine/threonine protein-kinase cdk11
Gene names
Name:cdk11
ORF Names:DDB_G0283279
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length358 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 358358Cyclin-dependent kinase 11
PRO_0000353101

Regions

Domain52 – 336285Protein kinase
Nucleotide binding58 – 669ATP By similarity

Sites

Active site1761Proton acceptor By similarity
Binding site811ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q54RB2 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 8458157B95470084

FASTA35841,358
        10         20         30         40         50         60 
MSNIQENENK ETCNIKENEN KEILKENFKN KEKQYFSSLR SPYSACRSVD CFKKLYTINE 

        70         80         90        100        110        120 
GAFGVVYCAQ DKETEEIVAL KKIKMERERE GIPITSVREI KVLMELKHDN IVQIKEIVLG 

       130        140        150        160        170        180 
KNINSIFMAM EFIDHDLRGL MEVIKKPFLP SEIKTLIQQL LNGVSYMHDN WVIHRDLKTA 

       190        200        210        220        230        240 
NLLYTNKGVL KIADFGLARE YGSPLKPLSK GVVTLWYRAP ELLLDTEIYT PAIDIWSVGC 

       250        260        270        280        290        300 
IFAEIISKEV LLQGSSEIDQ MDKIFKLFGT PTEKSWPAFF KLPLAKYFNL TDQPYNNLKS 

       310        320        330        340        350 
KFPHITDNAF DLLNKLLELN PEARISASDA LKHPYFFENP QPRDPLLMPT WPSSHKKT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000052 Genomic DNA. Translation: EAL65780.1.

3D structure databases

ProteinModelPortalQ54RB2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDB_0216376.

Proteomic databases

PRIDEQ54RB2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0216376; DDB0216376; DDB_G0283279.
KEGGddi:DDB_G0283279.

Organism-specific databases

dictyBaseDDB_G0283279. cdk11.

Phylogenomic databases

eggNOGCOG0515.
KOK08818.
OMAINEGAFG.
PhylomeDBQ54RB2.
ProtClustDBCLSZ2430383.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCDK11_DICDI
AccessionPrimary (citable) accession number: Q54RB2
Entry history
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: May 24, 2005
Last modified: April 16, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase