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Protein

Cyclin-dependent kinase 11

Gene

cdk11

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei81ATPPROSITE-ProRule annotation1
Active sitei176Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi58 – 66ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinase 11 (EC:2.7.11.22)
Alternative name(s):
Cell division cycle protein kinase 11
Cell division protein kinase 11
PITSVRE serine/threonine protein-kinase cdk11
Gene namesi
Name:cdk11
ORF Names:DDB_G0283279
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 4, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0283279 cdk11

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003531011 – 358Cyclin-dependent kinase 11Add BLAST358

Proteomic databases

PaxDbiQ54RB2
PRIDEiQ54RB2

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0216376

Structurei

3D structure databases

ProteinModelPortaliQ54RB2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini52 – 336Protein kinasePROSITE-ProRule annotationAdd BLAST285

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0663 Eukaryota
ENOG410XQ50 LUCA
InParanoidiQ54RB2
KOiK08818
OMAiMTDKGCI
PhylomeDBiQ54RB2

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

Q54RB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNIQENENK ETCNIKENEN KEILKENFKN KEKQYFSSLR SPYSACRSVD
60 70 80 90 100
CFKKLYTINE GAFGVVYCAQ DKETEEIVAL KKIKMERERE GIPITSVREI
110 120 130 140 150
KVLMELKHDN IVQIKEIVLG KNINSIFMAM EFIDHDLRGL MEVIKKPFLP
160 170 180 190 200
SEIKTLIQQL LNGVSYMHDN WVIHRDLKTA NLLYTNKGVL KIADFGLARE
210 220 230 240 250
YGSPLKPLSK GVVTLWYRAP ELLLDTEIYT PAIDIWSVGC IFAEIISKEV
260 270 280 290 300
LLQGSSEIDQ MDKIFKLFGT PTEKSWPAFF KLPLAKYFNL TDQPYNNLKS
310 320 330 340 350
KFPHITDNAF DLLNKLLELN PEARISASDA LKHPYFFENP QPRDPLLMPT

WPSSHKKT
Length:358
Mass (Da):41,358
Last modified:May 24, 2005 - v1
Checksum:i8458157B95470084
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000052 Genomic DNA Translation: EAL65780.1
RefSeqiXP_639135.1, XM_634043.1

Genome annotation databases

EnsemblProtistsiEAL65780; EAL65780; DDB_G0283279
GeneIDi8624005
KEGGiddi:DDB_G0283279

Entry informationi

Entry nameiCDK11_DICDI
AccessioniPrimary (citable) accession number: Q54RB2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: May 24, 2005
Last modified: March 28, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health