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Q54R42 (DUSP2_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable dual specificity protein phosphatase DDB_G0283417

EC=3.1.3.16
EC=3.1.3.48
Gene names
ORF Names:DDB_G0283417
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length230 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has a dual specificity toward Ser/Thr and Tyr-containing proteins By similarity.

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

Contains 1 tyrosine-protein phosphatase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 230230Probable dual specificity protein phosphatase DDB_G0283417
PRO_0000332951

Regions

Domain78 – 229152Tyrosine-protein phosphatase
Compositional bias75 – 806Poly-Asn

Sites

Active site1741Phosphocysteine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q54R42 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 1BD80BC8D911F2AC

FASTA23026,189
        10         20         30         40         50         60 
MVNLEELSLK RNNMKRTETT FTDISGKRYQ VANINEENSE SNRIELNRTS GFVIDTKPDD 

        70         80         90        100        110        120 
LSHKIEIIIP QSILNNNNNN YESINLYIGS QDAAFNKLDL QLKNIKSILN VGIGINNLFT 

       130        140        150        160        170        180 
KENSDINDGF IINYCNVEIF DDVNFNIIEK FDKCFEFIDS NIGGVENNGI LVHCNAGVSR 

       190        200        210        220        230 
SATILISYLM KKLKIPLSLS LEILKSSRPQ CKPNQGFLKQ LEIFEKELLF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000055 Genomic DNA. Translation: EAL65693.1.
RefSeqXP_639049.1. XM_633957.1.

3D structure databases

ProteinModelPortalQ54R42.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDBDRAFT_0185495.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0238562; DDB0238562; DDB_G0283417.
GeneID8624074.
KEGGddi:DDB_G0283417.

Organism-specific databases

dictyBaseDDB_G0283417.

Phylogenomic databases

eggNOGCOG2453.
OMAEAWSANG.
PhylomeDBQ54R42.

Family and domain databases

Gene3D3.90.190.10. 1 hit.
InterProIPR000340. Dual-sp_phosphatase_cat-dom.
IPR020422. Dual-sp_phosphatase_subgr_cat.
IPR024950. DUSP.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
[Graphical view]
PANTHERPTHR10159. PTHR10159. 1 hit.
PfamPF00782. DSPc. 1 hit.
[Graphical view]
SMARTSM00195. DSPc. 1 hit.
[Graphical view]
SUPFAMSSF52799. SSF52799. 1 hit.
PROSITEPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50054. TYR_PHOSPHATASE_DUAL. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROQ54R42.

Entry information

Entry nameDUSP2_DICDI
AccessionPrimary (citable) accession number: Q54R42
Entry history
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: May 24, 2005
Last modified: June 11, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase