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Q54QV7 (GSTA5_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative glutathione S-transferase alpha-5

EC=2.5.1.18
Alternative name(s):
GST class-alpha 5
Gene names
Name:gsta5
ORF Names:DDB_G0283575
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length198 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles By similarity.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Sequence similarities

Belongs to the GST superfamily. Alpha family.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Ontologies

Keywords
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 198198Putative glutathione S-transferase alpha-5
PRO_0000350742

Regions

Domain2 – 7877GST N-terminal
Domain80 – 198119GST C-terminal
Region49 – 502Glutathione binding By similarity
Region62 – 632Glutathione binding By similarity

Sites

Binding site81Glutathione By similarity

Sequences

Sequence LengthMass (Da)Tools
Q54QV7 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: A5B154C82270C654

FASTA19823,298
        10         20         30         40         50         60 
MTKPTLTYFP VRGRVQFPRC LLEYLGEEYN FNEVKTISDD LRKQLLFKQL PLYQEGDFKI 

        70         80         90        100        110        120 
VQTPAIIDYI SEKHDFRGKT KEERARAHQC LAGIMEVLDH CLGYSFKMDK QQQEKFRNES 

       130        140        150        160        170        180 
PIKKFFEGFE MVLSQNKYLA SGEKETYVDL MAFVMVDYVT NLGLMPSGDY PKLISLKKHY 

       190 
ESSPQLKKYL ESRPQSNF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000055 Genomic DNA. Translation: EAL65665.1.

3D structure databases

ProteinModelPortalQ54QV7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDB_0231408.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0231408; DDB0231408; DDB_G0283575.
KEGGddi:DDB_G0283575.

Organism-specific databases

dictyBaseDDB_G0283575.

Phylogenomic databases

eggNOGKOG1695.
KOK00799.
OMALRYLLEY.
PhylomeDBQ54QV7.
ProtClustDBCLSZ2430358.

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSTA5_DICDI
AccessionPrimary (citable) accession number: Q54QV7
Entry history
Integrated into UniProtKB/Swiss-Prot: September 23, 2008
Last sequence update: May 24, 2005
Last modified: April 16, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase