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Protein

Putative glutathione S-transferase alpha-5

Gene

gsta5

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei8GlutathioneBy similarity1
Binding sitei42GlutathioneBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionTransferase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative glutathione S-transferase alpha-5 (EC:2.5.1.18)
Alternative name(s):
GST class-alpha 5
Gene namesi
Name:gsta5
ORF Names:DDB_G0283575
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 4, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0283575

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003507421 – 198Putative glutathione S-transferase alpha-5Add BLAST198

Proteomic databases

PaxDbiQ54QV7

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0231408

Structurei

3D structure databases

ProteinModelPortaliQ54QV7
SMRiQ54QV7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 78GST N-terminalAdd BLAST77
Domaini80 – 198GST C-terminalAdd BLAST119

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni49 – 50Glutathione bindingBy similarity2
Regioni62 – 63Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Alpha family.Curated

Phylogenomic databases

eggNOGiENOG410IN5F Eukaryota
ENOG41127WC LUCA
InParanoidiQ54QV7
KOiK00799
OMAiNEMIIVL
PhylomeDBiQ54QV7

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF14497 GST_C_3, 1 hit
PF02798 GST_N, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q54QV7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKPTLTYFP VRGRVQFPRC LLEYLGEEYN FNEVKTISDD LRKQLLFKQL
60 70 80 90 100
PLYQEGDFKI VQTPAIIDYI SEKHDFRGKT KEERARAHQC LAGIMEVLDH
110 120 130 140 150
CLGYSFKMDK QQQEKFRNES PIKKFFEGFE MVLSQNKYLA SGEKETYVDL
160 170 180 190
MAFVMVDYVT NLGLMPSGDY PKLISLKKHY ESSPQLKKYL ESRPQSNF
Length:198
Mass (Da):23,298
Last modified:May 24, 2005 - v1
Checksum:iA5B154C82270C654
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000055 Genomic DNA Translation: EAL65665.1
RefSeqiXP_639027.1, XM_633935.1

Genome annotation databases

EnsemblProtistsiEAL65665; EAL65665; DDB_G0283575
GeneIDi8624155
KEGGiddi:DDB_G0283575

Entry informationi

Entry nameiGSTA5_DICDI
AccessioniPrimary (citable) accession number: Q54QV7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 23, 2008
Last sequence update: May 24, 2005
Last modified: March 28, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health