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Protein

Probable acid phosphatase DDB_G0284753

Gene

DDB_G0284753

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei81 – 811NucleophileBy similarity
Active sitei347 – 3471Proton donorBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable acid phosphatase DDB_G0284753 (EC:3.1.3.2)
Gene namesi
ORF Names:DDB_G0284753
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195 Componentsi: Chromosome 4, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0284753.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 464464Probable acid phosphatase DDB_G0284753PRO_0000369256Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ54P72.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi18 – 2710Poly-Gly

Sequence similaritiesi

Belongs to the histidine acid phosphatase family.Curated

Phylogenomic databases

eggNOGiNOG235758.
InParanoidiQ54P72.
PhylomeDBiQ54P72.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00328. His_Phos_2. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q54P72-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSYFRKSQQ KVEENQNGGG GDGRGSGIKV ELQTNINSRD LKNEHSDPKF
60 70 80 90 100
KFSPLRSTDV HLEDYDNEKY KLKFIQIVTR HGRRTPESNR TPLTMWMCNS
110 120 130 140 150
MDHLISNKDS PRPNCNPGQL TVLGIVDQIN VGKIYRKLFI DHLGFLDSQY
160 170 180 190 200
NKDQIFIRST NTTRTISSAR SLMHGLYGGS FTDEQEKSPH HSSFLVKPDN
210 220 230 240 250
EENMYPRNSK KLVFLKNLIK QHPKVIKENQ LSELEKFTEK INKIFENSKP
260 270 280 290 300
EESSFRARGF RSYAGLVNSF DCFRNNGLPI PKGLTKDIIQ RMYEESAKEF
310 320 330 340 350
KSARYFPEMS ILGIGRFVDD LNKELKLKAR NDPSVKDLKL SLYSGHDTTL
360 370 380 390 400
AALLVGYDMY EDKIHPVTSS TLEFLLMQDK DYKEPEVVKI TKSIEKELIN
410 420 430 440 450
HQYVKVIYNH KPIHIGPCKD KEVDGMCPLS EFLKISQSII PTNYDEQSKL
460
TQLDKKRYLS LIED
Length:464
Mass (Da):53,626
Last modified:May 24, 2005 - v1
Checksum:i90176186B58DFB51
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000071 Genomic DNA. Translation: EAL65029.1.
RefSeqiXP_638386.1. XM_633294.1.

Genome annotation databases

EnsemblProtistsiDDB0186172; DDB0186172; DDB_G0284753.
GeneIDi8624755.
KEGGiddi:DDB_G0284753.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000071 Genomic DNA. Translation: EAL65029.1.
RefSeqiXP_638386.1. XM_633294.1.

3D structure databases

ProteinModelPortaliQ54P72.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiDDB0186172; DDB0186172; DDB_G0284753.
GeneIDi8624755.
KEGGiddi:DDB_G0284753.

Organism-specific databases

dictyBaseiDDB_G0284753.

Phylogenomic databases

eggNOGiNOG235758.
InParanoidiQ54P72.
PhylomeDBiQ54P72.

Miscellaneous databases

PROiQ54P72.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00328. His_Phos_2. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiY4753_DICDI
AccessioniPrimary (citable) accession number: Q54P72
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 24, 2005
Last modified: January 7, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.