Q54P72 (Y4753_DICDI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable acid phosphatase DDB_G0284753
EC=3.1.3.2

Gene names

ORF Names:

DDB_G0284753

Organism

Dictyostelium discoideum (Slime mold) [Reference proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	464 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	A phosphate monoester + H2O = an alcohol + phosphate.
Sequence similarities	Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	acid phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 464	464	Probable acid phosphatase DDB_G0284753		PRO_0000369256
Regions
	Compositional bias	18 – 27	10	Poly-Gly
Sites
	Active site	81	1	Nucleophile By similarity
	Active site	347	1	Proton donor By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q54P72 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 90176186B58DFB51	FASTA	464	53,626
	10 20 30 40 50 60 MFSYFRKSQQ KVEENQNGGG GDGRGSGIKV ELQTNINSRD LKNEHSDPKF KFSPLRSTDV 70 80 90 100 110 120 HLEDYDNEKY KLKFIQIVTR HGRRTPESNR TPLTMWMCNS MDHLISNKDS PRPNCNPGQL 130 140 150 160 170 180 TVLGIVDQIN VGKIYRKLFI DHLGFLDSQY NKDQIFIRST NTTRTISSAR SLMHGLYGGS 190 200 210 220 230 240 FTDEQEKSPH HSSFLVKPDN EENMYPRNSK KLVFLKNLIK QHPKVIKENQ LSELEKFTEK 250 260 270 280 290 300 INKIFENSKP EESSFRARGF RSYAGLVNSF DCFRNNGLPI PKGLTKDIIQ RMYEESAKEF 310 320 330 340 350 360 KSARYFPEMS ILGIGRFVDD LNKELKLKAR NDPSVKDLKL SLYSGHDTTL AALLVGYDMY 370 380 390 400 410 420 EDKIHPVTSS TLEFLLMQDK DYKEPEVVKI TKSIEKELIN HQYVKVIYNH KPIHIGPCKD 430 440 450 460 KEVDGMCPLS EFLKISQSII PTNYDEQSKL TQLDKKRYLS LIED

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAFI02000071 Genomic DNA. Translation: EAL65029.1.
RefSeq	XP_638386.1. XM_633294.1.
3D structure databases
HSSP	HSSP built from PDB template 1ND5 based on UniProtKB P15309.
ProteinModelPortal	Q54P72.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	DDB0186172; DDB0186172; DDB_G0284753.
GeneID	8624755.
KEGG	ddi:DDB_G0284753.
Organism-specific databases
dictyBase	DDB_G0284753.
Phylogenomic databases
eggNOG	NOG235758.
InParanoid	Q54P72.
ProtClustDB	CLSZ2430220.
Family and domain databases
InterPro	IPR000560. His_Pase_superF_clade-2. [Graphical view]
Pfam	PF00328. His_Phos_2. 1 hit. [Graphical view]
PROSITE	PS00616. HIS_ACID_PHOSPHAT_1. 1 hit. PS00778. HIS_ACID_PHOSPHAT_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y4753_DICDI

Accession

Primary (citable) accession number: Q54P72

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	May 24, 2005
Last modified:	March 6, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)