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Protein

Probable acid phosphatase DDB_G0284755

Gene

DDB_G0284755

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei94 – 941NucleophileBy similarity
Active sitei359 – 3591Proton donorBy similarity

GO - Molecular functioni

  1. acid phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable acid phosphatase DDB_G0284755 (EC:3.1.3.2)
Gene namesi
ORF Names:DDB_G0284755
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 4, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0284755.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 473473Probable acid phosphatase DDB_G0284755PRO_0000369255Add
BLAST

Proteomic databases

PRIDEiQ54P71.

Structurei

3D structure databases

ProteinModelPortaliQ54P71.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi19 – 4224Asn-richAdd
BLAST

Sequence similaritiesi

Belongs to the histidine acid phosphatase family.Curated

Phylogenomic databases

eggNOGiNOG235758.
InParanoidiQ54P71.
KOiK01078.
OMAiERTISSA.
PhylomeDBiQ54P71.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00328. His_Phos_2. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q54P71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIINFLLNSI VGTVKLDENP NINLKNNINN NDNNKENSIE INDYLQTLVK
60 70 80 90 100
EEDFKNQHTD PNFKFLALRS TKVPIDEYNP ENYQLKFVQI ITRHGRRTPE
110 120 130 140 150
SKRYPLTMWT CNSLDQLITN KDTSRPDCNM GQLTVLGIVD QINVGKAYRN
160 170 180 190 200
LFINNLHFLD NKYNKDQIFI RSSNRERTIS SARSFMHGLY GGSFADDQEK
210 220 230 240 250
SPNHSSFLIL DEKDENMYPR SSPKYNFLKG LLKKHKAVIE ENEKSNLKEF
260 270 280 290 300
TEKIKNIFED SKFDTAFYVP SWRSYAGLVN SFDCFRNNGL PLPKGFTNDV
310 320 330 340 350
IQRMYEESAK EFKSARLFPE MSILGIGRFV NDLTKQMYLK SVNDPSVKDL
360 370 380 390 400
KLSLYSGHDT TLAALLVAYD MYEDNVHPVT SSALEYLLFQ DKNYKEPEVV
410 420 430 440 450
TKSNEKELIN HQYVKVIFNH KPIHIGPCKD KEVDGMCPLS EFLKISQSII
460 470
PTNYDEQSKI TDEEKNKYIQ EST
Length:473
Mass (Da):54,859
Last modified:April 14, 2009 - v2
Checksum:iAE73C64497CD293A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000071 Genomic DNA. Translation: EAL65030.2.
RefSeqiXP_638387.2. XM_633295.2.

Genome annotation databases

EnsemblProtistsiDDB0302470; DDB0302470; DDB_G0284755.
GeneIDi8624756.
KEGGiddi:DDB_G0284755.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000071 Genomic DNA. Translation: EAL65030.2.
RefSeqiXP_638387.2. XM_633295.2.

3D structure databases

ProteinModelPortaliQ54P71.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ54P71.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiDDB0302470; DDB0302470; DDB_G0284755.
GeneIDi8624756.
KEGGiddi:DDB_G0284755.

Organism-specific databases

dictyBaseiDDB_G0284755.

Phylogenomic databases

eggNOGiNOG235758.
InParanoidiQ54P71.
KOiK01078.
OMAiERTISSA.
PhylomeDBiQ54P71.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00328. His_Phos_2. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiY4755_DICDI
AccessioniPrimary (citable) accession number: Q54P71
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 14, 2009
Last modified: January 7, 2015
This is version 48 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.