Q54P71 (Y4755_DICDI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable acid phosphatase DDB_G0284755
EC=3.1.3.2

Gene names

ORF Names:

DDB_G0284755

Organism

Dictyostelium discoideum (Slime mold) [Reference proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	473 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	A phosphate monoester + H2O = an alcohol + phosphate.
Sequence similarities	Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	acid phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 473	473	Probable acid phosphatase DDB_G0284755		PRO_0000369255
Regions
	Compositional bias	19 – 42	24	Asn-rich
Sites
	Active site	94	1	Nucleophile By similarity
	Active site	359	1	Proton donor By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q54P71 [UniParc]. Last modified April 14, 2009. Version 2. Checksum: AE73C64497CD293A	FASTA	473	54,859
	10 20 30 40 50 60 MIINFLLNSI VGTVKLDENP NINLKNNINN NDNNKENSIE INDYLQTLVK EEDFKNQHTD 70 80 90 100 110 120 PNFKFLALRS TKVPIDEYNP ENYQLKFVQI ITRHGRRTPE SKRYPLTMWT CNSLDQLITN 130 140 150 160 170 180 KDTSRPDCNM GQLTVLGIVD QINVGKAYRN LFINNLHFLD NKYNKDQIFI RSSNRERTIS 190 200 210 220 230 240 SARSFMHGLY GGSFADDQEK SPNHSSFLIL DEKDENMYPR SSPKYNFLKG LLKKHKAVIE 250 260 270 280 290 300 ENEKSNLKEF TEKIKNIFED SKFDTAFYVP SWRSYAGLVN SFDCFRNNGL PLPKGFTNDV 310 320 330 340 350 360 IQRMYEESAK EFKSARLFPE MSILGIGRFV NDLTKQMYLK SVNDPSVKDL KLSLYSGHDT 370 380 390 400 410 420 TLAALLVAYD MYEDNVHPVT SSALEYLLFQ DKNYKEPEVV TKSNEKELIN HQYVKVIFNH 430 440 450 460 470 KPIHIGPCKD KEVDGMCPLS EFLKISQSII PTNYDEQSKI TDEEKNKYIQ EST

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAFI02000071 Genomic DNA. Translation: EAL65030.2.
RefSeq	XP_638387.2. XM_633295.2.
3D structure databases
HSSP	HSSP built from PDB template 1ND5 based on UniProtKB P15309.
ProteinModelPortal	Q54P71.
ModBase	Search...
Proteomic databases
PRIDE	Q54P71.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	DDB0302470; DDB0302470; DDB_G0284755.
GeneID	8624756.
KEGG	ddi:DDB_G0284755.
Organism-specific databases
dictyBase	DDB_G0284755.
Phylogenomic databases
eggNOG	NOG235758.
KO	K01078.
OMA	WPPFTSH.
ProtClustDB	CLSZ2430220.
Family and domain databases
InterPro	IPR000560. His_Pase_superF_clade-2. [Graphical view]
Pfam	PF00328. His_Phos_2. 1 hit. [Graphical view]
PROSITE	PS00616. HIS_ACID_PHOSPHAT_1. 1 hit. PS00778. HIS_ACID_PHOSPHAT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y4755_DICDI

Accession

Primary (citable) accession number: Q54P71

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	April 14, 2009
Last modified:	March 6, 2013
This is version 37 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)