Reviewed, UniProtKB/Swiss-Prot Q54NL1 (ABCC9_DICDI)

Names and origin

Protein names

Recommended name:
    ABC transporter C family member 9
Alternative name(s):
    ABC transporter ABCC.9

Gene names

Name:	abcC9
ORF Names:	DDB_G0285165

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	1345 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. [View classification] Contains 2 ABC transmembrane type-1 domains. Contains 2 ABC transporter domains.

Ontologies

Keywords
Biological process	Transport
Cellular component	Membrane
Domain	Coiled coil Repeat Transmembrane
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	slug development during sorocarp development Inferred from mutant phenotype. Source: dictyBase transmembrane transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of substances Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1345	1345	ABC transporter C family member 9		PRO_0000363854
Regions
	Transmembrane	139 – 159	21	Potential
	Transmembrane	172 – 192	21	Potential
	Transmembrane	246 – 266	21	Potential
	Transmembrane	268 – 288	21	Potential
	Transmembrane	356 – 376	21	Potential
	Transmembrane	402 – 422	21	Potential
	Transmembrane	776 – 796	21	Potential
	Transmembrane	817 – 837	21	Potential
	Transmembrane	906 – 926	21	Potential
	Transmembrane	1008 – 1028	21	Potential
	Domain	135 – 419	285	ABC transmembrane type-1 1
	Domain	481 – 703	223	ABC transporter 1
	Domain	775 – 1060	286	ABC transmembrane type-1 2
	Domain	1103 – 1338	236	ABC transporter 2
	Nucleotide binding	1137 – 1144	8	ATP Potential
	Coiled coil	21 – 55	35	Potential
	Coiled coil	709 – 739	31	Potential
	Compositional bias	467 – 477	11	Poly-Asp
Experimental info
	Sequence conflict	273	1	S → P in AAL85712. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q54NL1-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 54E539F9382C372E	FASTA	1,345	154,402
	10 20 30 40 50 60 MIRNKIKNKK SKSDYYSEIS LEEEEDKEEE IKDKKVLSKE EIKENENKNE KIKQTQCPED 70 80 90 100 110 120 NASLFSKITF GWITKLIVKA YIKKSLDIKD IFDVPNYLKS NYTSKFLTTE KQTFKRNTKY 130 140 150 160 170 180 SLILNIYINF ILLKNKKLIL IQFLRVLFTL LSPLILKLFI EFTQRIDSEK SIIEGIIYCG 190 200 210 220 230 240 LLFFSSFCSS LVDEYLVWFG MITSSQVKSC LTCLIFEKSL KLSNSAKVKY NAAKITNLIS 250 260 270 280 290 300 IDVDNFSNFF WSNSVEIFFQ PFQLIFLLIL LISEVGWSGF VGTAVILISF PINSYFGKKT 310 320 330 340 350 360 SDYYEKLLKY TDKRVSTTSE FINGIRFIKM YAWESLFLKK IEKQRKQELK ILLERGLFWL 370 380 390 400 410 420 GQIIIINTNS TFVFVATMVT YSLSGNKMKL ETAFTAMNIL DSIRILLIVM PYCYYSIMEL 430 440 450 460 470 480 IPSNKRIEKF LSTLEIQQNL QTTKNSNTIS INNGTFKWKD ENFEETDDDD DHDDDDDEGE 490 500 510 520 530 540 KEIEGKEEKE EINNFIFENI NFKAPIGKLT MICSPVGSGK TSLINALIGE IEKVNGEING 550 560 570 580 590 600 VPENISFTSQ QPFLLSTSLR ENILFGKELD IEYYKQVLDA CCLVSDLTQL SALDLTEIGE 610 620 630 640 650 660 GGINLSGGQK QRVSLARALY SNSDFILMDE PLSAVDPEVA NHLFEKCIQG MMKNKTRILV 670 680 690 700 710 720 THQIQFIPYA DHIVIIKDGK IIQGTYKELK DENGIDFESI IKTKNSNLNL NKTIKDEEEK 730 740 750 760 770 780 EDKEGEEKEE DKKEMILKLI KINYSDELKE KAKLLVEEDR NEGEVSFKTY KEYFYYGSSN 790 800 810 820 830 840 LFLFITLLVF LIGLIVNRLS DFWLTIWTEQ SFKEKSQTFY IICFVSIFIV SLILIFIRYS 850 860 870 880 890 900 LVAKIGFKSS KKLHDLLINS ISKSPIQFFD SNPSGRILNR FSNDISDIDT SMIDMFSDTL 910 920 930 940 950 960 EYIFAIVVGI FSIIYINPMT IVPFLILSMF YYQIFNIYRV SVRELNRCKS ISQSPIISFL 970 980 990 1000 1010 1020 SECCNGLSTI RAFKQQSRFI GIMNDNIDKN LKCEFASFAV EMWISIRLEL LSSIIVFIVS 1030 1040 1050 1060 1070 1080 LFSLFNGYSN SALSILSVST ARSITSYLKS ACRQMVDLER KMNSFERVNN YIKLPSEGSG 1090 1100 1110 1120 1130 1140 SGVKSMEFIS EKDLLNWPEK GNIQFNNVQV NYNSNSVPSL KDITFSVESN EKIGIVGRTG 1150 1160 1170 1180 1190 1200 AGKSTIANCL FRLVECSKGS ILIDGIDIKT IDLNKLRGSL GIVPQEPWLF SGTIRSNIDP 1210 1220 1230 1240 1250 1260 LNQYDDEMIW NYLEMVKLKK LIIEMPLKLN SKIHENGNTT LSYGQKQLLC LCRCLIKNPK 1270 1280 1290 1300 1310 1320 LIIMDEATSS VDFQTAETIK SVINENLVNN TILTIAHRLD IIIDSDKIAV IDNSKLIEFE 1330 1340 NPKNLINSNS KFRKIVNFQT KIQTN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evolutionary analyses of ABC transporters of Dictyostelium discoideum." Anjard C., Loomis W.F. Eukaryot. Cell 1:643-652(2002) [PubMed: 12456012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], NOMENCLATURE. Strain: AX4.
[2]	"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF474341 Genomic DNA. Translation: AAL85712.1. AAFI02000075 Genomic DNA. Translation: EAL64839.1.
RefSeq	XP_638351.1.
3D structure databases
HSSP	HSSP built from PDB template 2CBZ based on UniProtKB P33527.
ModBase	Search...
Genome annotation databases
GeneID	3389923.
GenomeReviews	Gene locus abcC9 in contig CM000153_GR.
KEGG	ddi:DDB_0216237.
Organism-specific databases
dictyBase	DDB_G0285165. abcC9.
Phylogenomic databases
HOGENOM	HBG758042.
InParanoid	Q54NL1.
OMA	TISINNG.
Family and domain databases
InterPro	IPR011527. ABC_TM_1. IPR001140. ABC_TM_transpt. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR017940. ABC_transporter_type1. IPR003593. ATPase_AAA+_core. [Graphical view]
Pfam	PF00664. ABC_membrane. 2 hits. PF00005. ABC_tran. 2 hits. [Graphical view]
SMART	SM00382. AAA. 2 hits. [Graphical view]
PROSITE	PS50929. ABC_TM1F. 2 hits. PS00211. ABC_TRANSPORTER_1. 2 hits. PS50893. ABC_TRANSPORTER_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABCC9_DICDI

Accession

Primary (citable) accession number: Q54NL1
Secondary accession number(s): Q8T6H0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	May 24, 2005
Last modified:	December 15, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)