Q54KZ1 (Q54KZ1_DICDI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Proline iminopeptidase RuleBase RU003421
EC=3.4.11.5 RuleBase RU003421

Gene names

ORF Names:

DDB_0187236, DDB_G0287013 EMBL EAL63933.1

Organism

Dictyostelium discoideum (Slime mold)

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Release of N-terminal proline from a peptide. RuleBase RU003421
Sequence similarities	Belongs to the peptidase S33 family. RuleBase RU003421

Ontologies

Keywords
Molecular function	Aminopeptidase RuleBase RU003421 Hydrolase Protease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro extracellular space Inferred from direct assay. Source: dictyBase
Molecular function	aminopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	135	1	Nucleophile By similarity PIRSR PIRSR006431-1
	Active site	291	1	By similarity PIRSR PIRSR006431-1
	Active site	320	1	Proton donor By similarity PIRSR PIRSR006431-1

Sequences

	Sequence		Length	Mass (Da)
	Q54KZ1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 77AFFED81A25FEC9	FASTA	341	38,622
	10 20 30 40 50 60 MTKKISEQVQ ELQEAQSTKT NVLSYPRSLY PPIEAYKVQK LKVSDIHEIY IEESGNPTGK 70 80 90 100 110 120 PVIVLHGGPG GGSEPMYRQY FDPVVYRIIQ FDQRGCGKST PFACLEDNNT WALVEDIEKI 130 140 150 160 170 180 RVLLGIDNWV VFGGSWGSTL SLAYAETHPS RVKALVLRGI FTLRREELIF FYQTGASFLF 190 200 210 220 230 240 ADYFDEYLKP IPPAERGDII SAYHRRLTGT DEKIKQEAAN AWTTWEMATS RLMVDKHKIA 250 260 270 280 290 300 RGEDPMFALA FARIENHYFV NAGFFREDGQ LINDAHILKN IPGVIVQGRY DVVCPMKSAW 310 320 330 340 DLKKVWGENA DLVIIPDSGH SCSENGIIHS LVEACDKFKH L

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." The Dictyostelium discoideum Sequencing Consortium Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAFI02000095 Genomic DNA. Translation: EAL63933.1.
RefSeq	XP_637441.1. XM_632349.1.
3D structure databases
ProteinModelPortal	Q54KZ1.
SMR	Q54KZ1. Positions 27-339.
ModBase	Search...
Protein-protein interaction databases
STRING	Q54KZ1.
Protein family/group databases
MEROPS	S33.001.
Proteomic databases
PRIDE	Q54KZ1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	DDB0187236; DDB0187236; DDB_G0287013.
GeneID	8625909.
KEGG	ddi:DDB_G0287013.
Organism-specific databases
dictyBase	DDB_G0287013.
Phylogenomic databases
eggNOG	euNOG04774.
GeneTree	EPrGT00050000005115.
HOGENOM	HBG677789.
InParanoid	Q54KZ1.
OMA	AELDWYY.
ProtClustDB	CLSZ2497154.
Family and domain databases
InterPro	IPR000073. AB_hydrolase_1. IPR005944. Pept_S33. IPR002410. Peptidase_S33. [Graphical view]
KO	K01259.
PANTHER	PTHR10992:SF12. PTHR10992:SF12. 1 hit.
Pfam	PF00561. Abhydrolase_1. 1 hit. [Graphical view]
PIRSF	PIRSF006431. Pept_S33. 1 hit.
PRINTS	PR00111. ABHYDROLASE. PR00793. PROAMNOPTASE.
TIGRFAMs	TIGR01249. Pro_imino_pep_1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q54KZ1_DICDI

Accession

Primary (citable) accession number: Q54KZ1

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	November 16, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)