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Q54K91 (ACH1_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acetyl-CoA hydrolase

EC=3.1.2.1
Alternative name(s):
Acetyl-CoA deacylase
Short name=Acetyl-CoA acylase
Gene names
Name:ach1
ORF Names:DDB_G0287519
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length532 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Presumably involved in regulating the intracellular acetyl-CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation By similarity.

Catalytic activity

Acetyl-CoA + H2O = CoA + acetate.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the acetyl-CoA hydrolase/transferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processacetyl-CoA metabolic process

Inferred from sequence or structural similarity. Source: dictyBase

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionacetyl-CoA hydrolase activity

Inferred from sequence or structural similarity. Source: dictyBase

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 532532Acetyl-CoA hydrolase
PRO_0000330918

Sequences

Sequence LengthMass (Da)Tools
Q54K91 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: BA70191A19871714

FASTA53258,894
        10         20         30         40         50         60 
MHKIVQQGSK SLIESRIKRK SLLSKVVTDV SQLIPYFQNG HYVSMGGFAG TGYPKVVPIA 

        70         80         90        100        110        120 
LADHVEKNGL QGKLKMNLFV GASVGPETED RWAMLDMIDK RYPHQNGHHI RNGINSGRIR 

       130        140        150        160        170        180 
FADQHLSTFA SDLLAGYYTL DKPHGSKRTM DIAIVEATEI TEDGCIVPGA SVGITPEILQ 

       190        200        210        220        230        240 
MADKIIIEIN TSLPSFKGLH DMVKIALPPF SKPYQITRVD DRIGLEAFPV DPEKIIAIVE 

       250        260        270        280        290        300 
SQLPDNTSVG APEDETSSAI ANNIVQFFIH EIEQGRFPKN LLPLQSGIGS IANAVIGGLS 

       310        320        330        340        350        360 
KGPFDNLSVW TEVIQDTFLD FFDNGKLKFA SATSLRFSPP GFNRLFNNWE NYKSKIILRN 

       370        380        390        400        410        420 
QAISNAAELI SRVGCIALNT PCEVDIYGHV NSTNTMGSKM LNGLGGSGEF LRNSRISIVH 

       430        440        450        460        470        480 
TPSTRPTKTD PHGISCIVPF ASHIDHTEHD IDIIVTEQGL ADIRGLAPYE RAKVIIQNCA 

       490        500        510        520        530 
HPIYKPILME YLETSRQICL KNHMGHEPHQ LDKAFKFYTN LSEKGTMKID KW 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000102 Genomic DNA. Translation: EAL63659.1.

3D structure databases

ProteinModelPortalQ54K91.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDB_0233380.

Proteomic databases

PRIDEQ54K91.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0233380; DDB0233380; DDB_G0287519.
KEGGddi:DDB_G0287519.

Organism-specific databases

dictyBaseDDB_G0287519.

Phylogenomic databases

eggNOGCOG0427.
KOK01067.
OMAPHQVGKP.
PhylomeDBQ54K91.
ProtClustDBCLSZ2429985.

Family and domain databases

InterProIPR026888. AcetylCoA_hyd_C.
IPR003702. ActCoA_hydro.
[Graphical view]
PANTHERPTHR21432:SF10. PTHR21432:SF10. 1 hit.
PfamPF13336. AcetylCoA_hyd_C. 1 hit.
PF02550. AcetylCoA_hydro. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROQ54K91.

Entry information

Entry nameACH1_DICDI
AccessionPrimary (citable) accession number: Q54K91
Entry history
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: May 24, 2005
Last modified: April 16, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase