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Protein

ABC transporter C family member 14

Gene

abcC14

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi522 – 529ATPPROSITE-ProRule annotation8
Nucleotide bindingi1105 – 1112ATPPROSITE-ProRule annotation8

GO - Molecular functioni

  • ATPase activity, coupled to transmembrane movement of substances Source: dictyBase
  • ATP binding Source: UniProtKB-KW
  • transporter activity Source: dictyBase

GO - Biological processi

  • sorocarp morphogenesis Source: dictyBase
  • transmembrane transport Source: GO_Central
  • transport Source: dictyBase

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DDI-382556. ABC-family proteins mediated transport.

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter C family member 14
Alternative name(s):
ABC transporter ABCC.14
Gene namesi
Name:abcC14
ORF Names:DDB_G0287589
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 5, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0287589. abcC14.

Subcellular locationi

Q54K24:
  • Membrane PROSITE-ProRule annotation; Multi-pass membrane protein PROSITE-ProRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei127 – 147HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei156 – 176HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei249 – 269HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei341 – 361HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei375 – 395HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei734 – 754HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei778 – 798HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei871 – 891HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei969 – 989HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei992 – 1012HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003638581 – 1317ABC transporter C family member 14Add BLAST1317

Proteomic databases

PaxDbiQ54K24.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0219976.

Structurei

3D structure databases

ProteinModelPortaliQ54K24.
SMRiQ54K24.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini119 – 404ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST286
Domaini490 – 710ABC transporter 1PROSITE-ProRule annotationAdd BLAST221
Domaini744 – 1027ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST284
Domaini1071 – 1306ABC transporter 2PROSITE-ProRule annotationAdd BLAST236

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi427 – 449Poly-AsnAdd BLAST23

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0054. Eukaryota.
COG1132. LUCA.
InParanoidiQ54K24.
OMAiDIFISRW.
PhylomeDBiQ54K24.

Family and domain databases

Gene3Di1.20.1560.10. 2 hits.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR036640. ABC1_TM_sf.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q54K24-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFINSFETKI KKKFSLLYEK LDDEDENEPS SSPSNSTNNF YKACPEDNSS
60 70 80 90 100
KWSKISFNWV TKLIMKGYFK ESLEMNDIYD LPELNKVQTT SKLLDDINFS
110 120 130 140 150
NGSKYALIKH IYKNFLPKNK YALISNIFIT IFIFLSPICL KFLINYISTD
160 170 180 190 200
NDNEKSILKG ILLCCLLCIS ILGQSISQEL FYWFGMKNSF DVRGALTAKI
210 220 230 240 250
FEKTLKLSNV SKKKYRSGKI MNIMSIDVEN ISEFFWTYYL DIVSHTLQIL
260 270 280 290 300
ILLGLLCYVV GPSGLVGFGV MVIALPINTM LCTKSSNYLE KSLEYSDSRT
310 320 330 340 350
NLTSELITNI RPFKMYAWEN LFINKIEEQR KQELKFLFLR VLFWIFDHMM
360 370 380 390 400
IETNATLVLV STFATYSLTG NTMSLDVTFT AMTIFANLKL PLIYLPEDIY
410 420 430 440 450
KAIGLMPSVK RIQNFLKSSE SLKSKENNQN INFNNNNNNN NNNKNNNNND
460 470 480 490 500
DNDIIIENCT FQWNEPENNN LFEFNQSEDE EENEEEEEEE NEENIKINEN
510 520 530 540 550
FDYKLNDINL IVPKGKLTMI CGVVGSGKTS LVCGLIGEIY KLNGSVSGVP
560 570 580 590 600
NNISFTSQQP FLLSASLREN ILFGNEFDIE RYKKVIESTA LTKDIVNLAG
610 620 630 640 650
LDLTEIGERG INLSGGQKQR ISLARALYAN SDCFIFDEPL SAVDPEVASH
660 670 680 690 700
LFDHCIQGID FKSILKTKEI KKNVENETDS EELIKNEIEI ENEIIDVNNV
710 720 730 740 750
ISDKNDPNLI EKAKLLVKED KNEGEVEFNV YKKYFSYGTS GVTLFITISL
760 770 780 790 800
FFIGQAVYKV SDFWLAIWTE RSIEGKSDSF YIGYYLLIIG IFVSLLMIRT
810 820 830 840 850
YSLSRITFGI GKNLHSALLK SVTYASCRFF DTNPSGRILN RFSKDTSDID
860 870 880 890 900
IHMLDLLSEV SICFSELTIG LISIVFIIPI IIIPLTLLFI IYYIYQRLYR
910 920 930 940 950
PSARELNRWE SITLSPVFSL LQECYNGLLT IRTYKQESRF IKEMFDNINI
960 970 980 990 1000
NLGCIFYSFA VHRWISMRLE VMGCIMVFFT SLAAALFTSN NGLAALSVTT
1010 1020 1030 1040 1050
ALSLNGYLSW GVRRIVELEV KMNSFQRIQS YIEIPKEGNK LISTGTNQVD
1060 1070 1080 1090 1100
SDGLKTISNG DLVNWPNKGI IEFKNVEIKY RPNSEPNLKD LSFKVQSSEK
1110 1120 1130 1140 1150
IGIVGRTGAG KTTIASSLFR MVECSKGLIL IDGIDISKVQ LQKLRSSIGI
1160 1170 1180 1190 1200
VPQDPFIFTG TIRSNIDPFN EFTDFEIWES IEKVKLKDAI NSMPLKLETA
1210 1220 1230 1240 1250
LQENGDNGFS YGQKQLLCLC RTILKNFKII LMDEATSSID YHTAQLIKQT
1260 1270 1280 1290 1300
IQENFKDCTT LTIAHRLETI IDCNKIAVID SGQLIEFDTP SNLMNIPNSK
1310
FNKLIKSQTD YSNNKIK
Length:1,317
Mass (Da):150,215
Last modified:May 24, 2005 - v1
Checksum:i03E7EE3DE8A3C995
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000103 Genomic DNA. Translation: EAL63603.1.
RefSeqiXP_637140.1. XM_632048.1.

Genome annotation databases

EnsemblProtistsiEAL63603; EAL63603; DDB_G0287589.
GeneIDi8626235.
KEGGiddi:DDB_G0287589.

Similar proteinsi

Entry informationi

Entry nameiABCCE_DICDI
AccessioniPrimary (citable) accession number: Q54K24
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: May 24, 2005
Last modified: October 25, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families