Reviewed, UniProtKB/Swiss-Prot Q54K24 (ABCCE_DICDI)

Names and origin

Protein names

Recommended name:
    ABC transporter C family member 14
Alternative name(s):
    ABC transporter ABCC.14

Gene names

Name:	abcC14
ORF Names:	DDB_G0287589

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	1317 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. [View classification] Contains 2 ABC transmembrane type-1 domains. Contains 2 ABC transporter domains.

Ontologies

Keywords
Biological process	Transport
Cellular component	Membrane
Domain	Repeat Transmembrane
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	transmembrane transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of substances Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1317	1317	ABC transporter C family member 14		PRO_0000363858
Regions
	Transmembrane	127 – 147	21	Potential
	Transmembrane	156 – 176	21	Potential
	Transmembrane	249 – 269	21	Potential
	Transmembrane	341 – 361	21	Potential
	Transmembrane	375 – 395	21	Potential
	Transmembrane	734 – 754	21	Potential
	Transmembrane	778 – 798	21	Potential
	Transmembrane	871 – 891	21	Potential
	Transmembrane	969 – 989	21	Potential
	Transmembrane	992 – 1012	21	Potential
	Domain	119 – 404	286	ABC transmembrane type-1 1
	Domain	490 – 710	221	ABC transporter 1
	Domain	744 – 1027	284	ABC transmembrane type-1 2
	Domain	1071 – 1306	236	ABC transporter 2
	Nucleotide binding	522 – 529	8	ATP Potential
	Nucleotide binding	1105 – 1112	8	ATP Potential
	Compositional bias	427 – 449	23	Poly-Asn

Sequences

	Sequence		Length	Mass (Da)
	Q54K24-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 03E7EE3DE8A3C995	FASTA	1,317	150,215
	10 20 30 40 50 60 MFINSFETKI KKKFSLLYEK LDDEDENEPS SSPSNSTNNF YKACPEDNSS KWSKISFNWV 70 80 90 100 110 120 TKLIMKGYFK ESLEMNDIYD LPELNKVQTT SKLLDDINFS NGSKYALIKH IYKNFLPKNK 130 140 150 160 170 180 YALISNIFIT IFIFLSPICL KFLINYISTD NDNEKSILKG ILLCCLLCIS ILGQSISQEL 190 200 210 220 230 240 FYWFGMKNSF DVRGALTAKI FEKTLKLSNV SKKKYRSGKI MNIMSIDVEN ISEFFWTYYL 250 260 270 280 290 300 DIVSHTLQIL ILLGLLCYVV GPSGLVGFGV MVIALPINTM LCTKSSNYLE KSLEYSDSRT 310 320 330 340 350 360 NLTSELITNI RPFKMYAWEN LFINKIEEQR KQELKFLFLR VLFWIFDHMM IETNATLVLV 370 380 390 400 410 420 STFATYSLTG NTMSLDVTFT AMTIFANLKL PLIYLPEDIY KAIGLMPSVK RIQNFLKSSE 430 440 450 460 470 480 SLKSKENNQN INFNNNNNNN NNNKNNNNND DNDIIIENCT FQWNEPENNN LFEFNQSEDE 490 500 510 520 530 540 EENEEEEEEE NEENIKINEN FDYKLNDINL IVPKGKLTMI CGVVGSGKTS LVCGLIGEIY 550 560 570 580 590 600 KLNGSVSGVP NNISFTSQQP FLLSASLREN ILFGNEFDIE RYKKVIESTA LTKDIVNLAG 610 620 630 640 650 660 LDLTEIGERG INLSGGQKQR ISLARALYAN SDCFIFDEPL SAVDPEVASH LFDHCIQGID 670 680 690 700 710 720 FKSILKTKEI KKNVENETDS EELIKNEIEI ENEIIDVNNV ISDKNDPNLI EKAKLLVKED 730 740 750 760 770 780 KNEGEVEFNV YKKYFSYGTS GVTLFITISL FFIGQAVYKV SDFWLAIWTE RSIEGKSDSF 790 800 810 820 830 840 YIGYYLLIIG IFVSLLMIRT YSLSRITFGI GKNLHSALLK SVTYASCRFF DTNPSGRILN 850 860 870 880 890 900 RFSKDTSDID IHMLDLLSEV SICFSELTIG LISIVFIIPI IIIPLTLLFI IYYIYQRLYR 910 920 930 940 950 960 PSARELNRWE SITLSPVFSL LQECYNGLLT IRTYKQESRF IKEMFDNINI NLGCIFYSFA 970 980 990 1000 1010 1020 VHRWISMRLE VMGCIMVFFT SLAAALFTSN NGLAALSVTT ALSLNGYLSW GVRRIVELEV 1030 1040 1050 1060 1070 1080 KMNSFQRIQS YIEIPKEGNK LISTGTNQVD SDGLKTISNG DLVNWPNKGI IEFKNVEIKY 1090 1100 1110 1120 1130 1140 RPNSEPNLKD LSFKVQSSEK IGIVGRTGAG KTTIASSLFR MVECSKGLIL IDGIDISKVQ 1150 1160 1170 1180 1190 1200 LQKLRSSIGI VPQDPFIFTG TIRSNIDPFN EFTDFEIWES IEKVKLKDAI NSMPLKLETA 1210 1220 1230 1240 1250 1260 LQENGDNGFS YGQKQLLCLC RTILKNFKII LMDEATSSID YHTAQLIKQT IQENFKDCTT 1270 1280 1290 1300 1310 LTIAHRLETI IDCNKIAVID SGQLIEFDTP SNLMNIPNSK FNKLIKSQTD YSNNKIK

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AAFI02000103 Genomic DNA. Translation: EAL63603.1.
RefSeq	XP_637140.1.
3D structure databases
HSSP	HSSP built from PDB template 2CBZ based on UniProtKB P33527.
ModBase	Search...
Genome annotation databases
GeneID	3388726.
GenomeReviews	Gene locus abcC14 in contig CM000154_GR.
KEGG	ddi:DDB_0219976.
Organism-specific databases
dictyBase	DDB_G0287589. abcC14.
Phylogenomic databases
HOGENOM	HBG758042.
InParanoid	Q54K24.
OMA	IAINTEQ.
Family and domain databases
InterPro	IPR011527. ABC_TM_1. IPR001140. ABC_TM_transpt. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR017940. ABC_transporter_type1. IPR003593. ATPase_AAA+_core. [Graphical view]
Pfam	PF00664. ABC_membrane. 2 hits. PF00005. ABC_tran. 2 hits. [Graphical view]
SMART	SM00382. AAA. 2 hits. [Graphical view]
PROSITE	PS50929. ABC_TM1F. 2 hits. PS00211. ABC_TRANSPORTER_1. 2 hits. PS50893. ABC_TRANSPORTER_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABCCE_DICDI

Accession

Primary (citable) accession number: Q54K24

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	May 24, 2005
Last modified:	December 15, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)