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Protein

Probable ornithine aminotransferase

Gene

oatA

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.

Cofactori

Pathwayi: L-proline biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes L-glutamate 5-semialdehyde from L-ornithine.
Proteins known to be involved in this subpathway in this organism are:
  1. Probable ornithine aminotransferase (oatA)
This subpathway is part of the pathway L-proline biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-glutamate 5-semialdehyde from L-ornithine, the pathway L-proline biosynthesis and in Amino-acid biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase
LigandPyridoxal phosphate

Enzyme and pathway databases

ReactomeiR-DDI-70614 Amino acid synthesis and interconversion (transamination)
UniPathwayiUPA00098; UER00358

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ornithine aminotransferase (EC:2.6.1.13)
Alternative name(s):
Ornithine--oxo-acid aminotransferase
Gene namesi
Name:oatA
ORF Names:DDB_G0287913
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 5, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0287913 oatA

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003277751 – 416Probable ornithine aminotransferaseAdd BLAST416

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei267N6-(pyridoxal phosphate)lysineBy similarity1

Proteomic databases

PaxDbiQ54JP5
PRIDEiQ54JP5

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi44689.DDB0231478

Structurei

3D structure databases

ProteinModelPortaliQ54JP5
SMRiQ54JP5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1402 Eukaryota
COG4992 LUCA
InParanoidiQ54JP5
KOiK00819
OMAiRTAWDLC
PhylomeDBiQ54JP5

Family and domain databases

CDDicd00610 OAT_like, 1 hit
Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 2 hits
InterProiView protein in InterPro
IPR005814 Aminotrans_3
IPR010164 Orn_aminotrans
IPR034758 Orn_aminotrans_mito
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR11986:SF18 PTHR11986:SF18, 1 hit
PfamiView protein in Pfam
PF00202 Aminotran_3, 1 hit
PIRSFiPIRSF000521 Transaminase_4ab_Lys_Orn, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01885 Orn_aminotrans, 1 hit
PROSITEiView protein in PROSITE
PS00600 AA_TRANSFER_CLASS_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q54JP5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPISSQIQE CTSKELIEME SEFAAHTYHP IPVVFKKASG VHVWDVEEKQ
60 70 80 90 100
YFDFLSAYSA VNQGHSHPKI VSALITQAQK CALSSRAFYN EVFPQYAKYI
110 120 130 140 150
TEYFGYEMVL PMNTGAEAVE TSIKLARRWG YVKKGIAEDQ AIVISCKGCF
160 170 180 190 200
HGRTIGVISM SDDPSSYNKY GPLMNGIIKI DYNSTQQLEE VLSQHADRVC
210 220 230 240 250
GFIVEPIQGE AGVVVPDEGY LKKCYELCKK YNVLLVADEI QTGLCRTGRM
260 270 280 290 300
LCSDWDGIKP DLVLLGKAIS GGLLPISAVL GGKDVMLTIK PGEHGSTYGG
310 320 330 340 350
SPLASAVAMA ALDVLRDENL AENAQKLGEH FRAQISNINH PAIQLVRGKG
360 370 380 390 400
LLNAIVIDPN FTVSAWDICI KFAENGLLAK PTHDNIIRLA PPLTITLEQI
410
DQCVSIIKKV FDSFKN
Length:416
Mass (Da):45,752
Last modified:May 24, 2005 - v1
Checksum:i3C7765B82E5073D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000104 Genomic DNA Translation: EAL63485.1
RefSeqiXP_636989.1, XM_631897.1

Genome annotation databases

EnsemblProtistsiEAL63485; EAL63485; DDB_G0287913
GeneIDi8626361
KEGGiddi:DDB_G0287913

Similar proteinsi

Entry informationi

Entry nameiOAT_DICDI
AccessioniPrimary (citable) accession number: Q54JP5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: May 23, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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