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Q54JP5

- OAT_DICDI

UniProt

Q54JP5 - OAT_DICDI

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Protein

Probable ornithine aminotransferase

Gene

oatA

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.

Cofactori

Pathwayi

GO - Molecular functioni

  1. ornithine-oxo-acid transaminase activity Source: dictyBase
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. arginine catabolic process Source: dictyBase
  2. L-proline biosynthetic process Source: UniProtKB-UniPathway
  3. ornithine metabolic process Source: dictyBase
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

UniPathwayiUPA00098; UER00358.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ornithine aminotransferase (EC:2.6.1.13)
Alternative name(s):
Ornithine--oxo-acid aminotransferase
Gene namesi
Name:oatA
ORF Names:DDB_G0287913
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 5, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0287913. oatA.

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 416416Probable ornithine aminotransferasePRO_0000327775Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei267 – 2671N6-(pyridoxal phosphate)lysineBy similarity

Proteomic databases

PRIDEiQ54JP5.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB_0231478.

Structurei

3D structure databases

ProteinModelPortaliQ54JP5.
SMRiQ54JP5. Positions 12-414.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG4992.
InParanoidiQ54JP5.
KOiK00819.
OMAiDVMLTIK.
PhylomeDBiQ54JP5.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR005814. Aminotrans_3.
IPR010164. Orn_aminotrans.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PTHR11986:SF18. PTHR11986:SF18. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01885. Orn_aminotrans. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q54JP5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDPISSQIQE CTSKELIEME SEFAAHTYHP IPVVFKKASG VHVWDVEEKQ
60 70 80 90 100
YFDFLSAYSA VNQGHSHPKI VSALITQAQK CALSSRAFYN EVFPQYAKYI
110 120 130 140 150
TEYFGYEMVL PMNTGAEAVE TSIKLARRWG YVKKGIAEDQ AIVISCKGCF
160 170 180 190 200
HGRTIGVISM SDDPSSYNKY GPLMNGIIKI DYNSTQQLEE VLSQHADRVC
210 220 230 240 250
GFIVEPIQGE AGVVVPDEGY LKKCYELCKK YNVLLVADEI QTGLCRTGRM
260 270 280 290 300
LCSDWDGIKP DLVLLGKAIS GGLLPISAVL GGKDVMLTIK PGEHGSTYGG
310 320 330 340 350
SPLASAVAMA ALDVLRDENL AENAQKLGEH FRAQISNINH PAIQLVRGKG
360 370 380 390 400
LLNAIVIDPN FTVSAWDICI KFAENGLLAK PTHDNIIRLA PPLTITLEQI
410
DQCVSIIKKV FDSFKN
Length:416
Mass (Da):45,752
Last modified:May 24, 2005 - v1
Checksum:i3C7765B82E5073D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000104 Genomic DNA. Translation: EAL63485.1.
RefSeqiXP_636989.1. XM_631897.1.

Genome annotation databases

EnsemblProtistsiDDB0231478; DDB0231478; DDB_G0287913.
GeneIDi8626361.
KEGGiddi:DDB_G0287913.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000104 Genomic DNA. Translation: EAL63485.1 .
RefSeqi XP_636989.1. XM_631897.1.

3D structure databases

ProteinModelPortali Q54JP5.
SMRi Q54JP5. Positions 12-414.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 44689.DDB_0231478.

Proteomic databases

PRIDEi Q54JP5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0231478 ; DDB0231478 ; DDB_G0287913 .
GeneIDi 8626361.
KEGGi ddi:DDB_G0287913.

Organism-specific databases

dictyBasei DDB_G0287913. oatA.

Phylogenomic databases

eggNOGi COG4992.
InParanoidi Q54JP5.
KOi K00819.
OMAi DVMLTIK.
PhylomeDBi Q54JP5.

Enzyme and pathway databases

UniPathwayi UPA00098 ; UER00358 .

Miscellaneous databases

PROi Q54JP5.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProi IPR005814. Aminotrans_3.
IPR010164. Orn_aminotrans.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
PANTHERi PTHR11986. PTHR11986. 1 hit.
PTHR11986:SF18. PTHR11986:SF18. 1 hit.
Pfami PF00202. Aminotran_3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR01885. Orn_aminotrans. 1 hit.
PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiOAT_DICDI
AccessioniPrimary (citable) accession number: Q54JP5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: November 26, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3