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Q54JP5

- OAT_DICDI

UniProt

Q54JP5 - OAT_DICDI

Protein

Probable ornithine aminotransferase

Gene

oatA

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.

    Cofactori

    Pyridoxal phosphate.By similarity

    Pathwayi

    GO - Molecular functioni

    1. ornithine-oxo-acid transaminase activity Source: dictyBase
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. arginine catabolic process Source: dictyBase
    2. L-proline biosynthetic process Source: UniProtKB-UniPathway
    3. ornithine metabolic process Source: dictyBase

    Keywords - Molecular functioni

    Aminotransferase, Transferase

    Keywords - Ligandi

    Pyridoxal phosphate

    Enzyme and pathway databases

    UniPathwayiUPA00098; UER00358.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable ornithine aminotransferase (EC:2.6.1.13)
    Alternative name(s):
    Ornithine--oxo-acid aminotransferase
    Gene namesi
    Name:oatA
    ORF Names:DDB_G0287913
    OrganismiDictyostelium discoideum (Slime mold)
    Taxonomic identifieri44689 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
    ProteomesiUP000002195: Chromosome 5, UP000002195: Unassembled WGS sequence

    Organism-specific databases

    dictyBaseiDDB_G0287913. oatA.

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 416416Probable ornithine aminotransferasePRO_0000327775Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei267 – 2671N6-(pyridoxal phosphate)lysineBy similarity

    Proteomic databases

    PRIDEiQ54JP5.

    Interactioni

    Protein-protein interaction databases

    STRINGi44689.DDB_0231478.

    Structurei

    3D structure databases

    ProteinModelPortaliQ54JP5.
    SMRiQ54JP5. Positions 12-414.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG4992.
    KOiK00819.
    OMAiDVMLTIK.
    PhylomeDBiQ54JP5.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR005814. Aminotrans_3.
    IPR010164. Orn_aminotrans.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view]
    PANTHERiPTHR11986. PTHR11986. 1 hit.
    PTHR11986:SF18. PTHR11986:SF18. 1 hit.
    PfamiPF00202. Aminotran_3. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01885. Orn_aminotrans. 1 hit.
    PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q54JP5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDPISSQIQE CTSKELIEME SEFAAHTYHP IPVVFKKASG VHVWDVEEKQ    50
    YFDFLSAYSA VNQGHSHPKI VSALITQAQK CALSSRAFYN EVFPQYAKYI 100
    TEYFGYEMVL PMNTGAEAVE TSIKLARRWG YVKKGIAEDQ AIVISCKGCF 150
    HGRTIGVISM SDDPSSYNKY GPLMNGIIKI DYNSTQQLEE VLSQHADRVC 200
    GFIVEPIQGE AGVVVPDEGY LKKCYELCKK YNVLLVADEI QTGLCRTGRM 250
    LCSDWDGIKP DLVLLGKAIS GGLLPISAVL GGKDVMLTIK PGEHGSTYGG 300
    SPLASAVAMA ALDVLRDENL AENAQKLGEH FRAQISNINH PAIQLVRGKG 350
    LLNAIVIDPN FTVSAWDICI KFAENGLLAK PTHDNIIRLA PPLTITLEQI 400
    DQCVSIIKKV FDSFKN 416
    Length:416
    Mass (Da):45,752
    Last modified:May 24, 2005 - v1
    Checksum:i3C7765B82E5073D3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000104 Genomic DNA. Translation: EAL63485.1.
    RefSeqiXP_636989.1. XM_631897.1.

    Genome annotation databases

    EnsemblProtistsiDDB0231478; DDB0231478; DDB_G0287913.
    GeneIDi8626361.
    KEGGiddi:DDB_G0287913.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000104 Genomic DNA. Translation: EAL63485.1 .
    RefSeqi XP_636989.1. XM_631897.1.

    3D structure databases

    ProteinModelPortali Q54JP5.
    SMRi Q54JP5. Positions 12-414.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 44689.DDB_0231478.

    Proteomic databases

    PRIDEi Q54JP5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi DDB0231478 ; DDB0231478 ; DDB_G0287913 .
    GeneIDi 8626361.
    KEGGi ddi:DDB_G0287913.

    Organism-specific databases

    dictyBasei DDB_G0287913. oatA.

    Phylogenomic databases

    eggNOGi COG4992.
    KOi K00819.
    OMAi DVMLTIK.
    PhylomeDBi Q54JP5.

    Enzyme and pathway databases

    UniPathwayi UPA00098 ; UER00358 .

    Miscellaneous databases

    PROi Q54JP5.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR005814. Aminotrans_3.
    IPR010164. Orn_aminotrans.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view ]
    PANTHERi PTHR11986. PTHR11986. 1 hit.
    PTHR11986:SF18. PTHR11986:SF18. 1 hit.
    Pfami PF00202. Aminotran_3. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01885. Orn_aminotrans. 1 hit.
    PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the social amoeba Dictyostelium discoideum."
      Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
      , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
      Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX4.

    Entry informationi

    Entry nameiOAT_DICDI
    AccessioniPrimary (citable) accession number: Q54JP5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 8, 2008
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Dictyostelium discoideum
      Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3