Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Frizzled and smoothened-like protein E

Gene

fslE

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Keywordsi

Molecular functionReceptor

Names & Taxonomyi

Protein namesi
Recommended name:
Frizzled and smoothened-like protein E
Gene namesi
Name:fslE
ORF Names:DDB_G0288269
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 5, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0288269. fslE.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini21 – 259ExtracellularSequence analysisAdd BLAST239
Transmembranei260 – 280Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini281 – 288CytoplasmicSequence analysis8
Transmembranei289 – 309Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini310 – 337ExtracellularSequence analysisAdd BLAST28
Transmembranei338 – 358Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini359 – 365CytoplasmicSequence analysis7
Transmembranei366 – 386Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini387 – 408ExtracellularSequence analysisAdd BLAST22
Transmembranei409 – 429Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini430 – 457CytoplasmicSequence analysisAdd BLAST28
Transmembranei458 – 478Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini479 – 511ExtracellularSequence analysisAdd BLAST33
Transmembranei512 – 532Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini533 – 609CytoplasmicSequence analysisAdd BLAST77

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_000037136721 – 609Frizzled and smoothened-like protein EAdd BLAST589

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi40 ↔ 118By similarity
Disulfide bondi53 ↔ 111By similarity
Glycosylationi75N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi100 ↔ 149By similarity
Glycosylationi130N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi138 ↔ 189By similarity
Glycosylationi172N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi198N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi217N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi245N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ54J78.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 192FZAdd BLAST158

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi565 – 599Asn-richAdd BLAST35

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ54J78.
PhylomeDBiQ54J78.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q54J78-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEMIRIFLIY LILKIIIING ENNEYSKGYG VGIVFPGSKC LNYVGDSIGQ
60 70 80 90 100
PLCNNRLFNG GKKIYSTVTL VDNKNISSQE LSKIEILKSF EALTFLQDQC
110 120 130 140 150
DDLLFTQFGL CDLNFSPCVE TIPKITPLQN VSLPQRLCKS VCERMVSNCP
160 170 180 190 200
RLSLKIDCSI SFLFPEIGTE YNLTLYGYTE NKGLYKVPCI DPTDGYNNIS
210 220 230 240 250
NQMELIQACP YPLLLKNSSD PKYSPNKGYT YLPPTNCVLT CPMPNYTKTQ
260 270 280 290 300
WKRVYDMAKT LSSISFICAC YNILTFGILN RKRKSKYNIC ITLMSTSIAL
310 320 330 340 350
VYLTDIIKFG YGIEEFLCPE PGRSAVQNDA ACGITGAMFH FGITYCCCWA
360 370 380 390 400
MTMSIVLFCS VKRIKLFYFR HFMIGNTIFT IITTVILLSA KKMVAGTGYI
410 420 430 440 450
ECWVRERWFV ITLFWLPCGI GLSIGIFCIG GVIHEIYNIS KKVNIRESEF
460 470 480 490 500
ILRQIKPFSL VFSVAGSFLY LFIFFFDVER KIDSYKAAVA DYVLCLLSGG
510 520 530 540 550
SEETCFTTGP NYASFFIFYF FIRVFGVLFF SIYGTSRVAR DIWSEVVFDE
560 570 580 590 600
VRSRLSQSES GISRNNSRTD ISFGKNNNSK NSNNSKNSNN SKNSNNSDND

SKSIELEKK
Length:609
Mass (Da):69,006
Last modified:May 24, 2005 - v1
Checksum:i99C5FAE320F25F1C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000109 Genomic DNA. Translation: EAL63316.1.
RefSeqiXP_636809.1. XM_631717.1.

Genome annotation databases

EnsemblProtistsiEAL63316; EAL63316; DDB_G0288269.
GeneIDi8626526.
KEGGiddi:DDB_G0288269.

Similar proteinsi

Entry informationi

Entry nameiFSLE_DICDI
AccessioniPrimary (citable) accession number: Q54J78
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: May 24, 2005
Last modified: May 10, 2017
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  3. SIMILARITY comments
    Index of protein domains and families