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Q54IT3

- AOFA_DICDI

UniProt

Q54IT3 - AOFA_DICDI

Protein

Probable flavin-containing monoamine oxidase A

Gene

maoA

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2.

    Cofactori

    FAD.By similarity

    GO - Molecular functioni

    1. oxidoreductase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    FAD, Flavoprotein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable flavin-containing monoamine oxidase A (EC:1.4.3.4)
    Gene namesi
    Name:maoA
    ORF Names:DDB_G0288541
    OrganismiDictyostelium discoideum (Slime mold)
    Taxonomic identifieri44689 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
    ProteomesiUP000002195: Chromosome 5, UP000002195: Unassembled WGS sequence

    Organism-specific databases

    dictyBaseiDDB_G0288541. maoA.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 456456Probable flavin-containing monoamine oxidase APRO_0000328628Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei394 – 3941S-8alpha-FAD cysteineBy similarity

    Proteomic databases

    PRIDEiQ54IT3.

    Interactioni

    Protein-protein interaction databases

    STRINGi44689.DDB_0231707.

    Structurei

    3D structure databases

    ProteinModelPortaliQ54IT3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the flavin monoamine oxidase family.Curated

    Phylogenomic databases

    eggNOGiCOG1231.
    KOiK00274.
    OMAiREVLCAM.
    PhylomeDBiQ54IT3.

    Family and domain databases

    InterProiIPR002937. Amino_oxidase.
    IPR001613. Flavin_amine_oxidase.
    [Graphical view]
    PfamiPF01593. Amino_oxidase. 1 hit.
    [Graphical view]
    PRINTSiPR00757. AMINEOXDASEF.

    Sequencei

    Sequence statusi: Complete.

    Q54IT3-1 [UniParc]FASTAAdd to Basket

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    MSTLYDVVIV GGGLTGLNAA YQFKKAGLNV MVLKPKDRFG GRTESIKVED    50
    YWFDLGGQWM GGTHKYLKEL CDELGVKSFP QYDEGKHVLE INGKKVYYQG 100
    NISNLNKSYN LEGLFESISK IDELSAELNP DKPYAHSKSK EYDQLTVAQW 150
    VEKNVKGNDA RSIIDWFCRV CVAAEPTEVS FLFFLHFIRT AGNYGLLADI 200
    HGGAQQDRLI GGSQQISEGL AKKIGEKHYT LNAPVRSIIQ DANQCTIKTD 250
    NGSTYRSKYI VVAIPPTLAG RIHYSPSMPP RRDELTQRMP MGSVIKTITI 300
    YDEPFWRKEG YSAEAISDKG PIFICYDDSS HDDKKTAIVG FIAASAAKDW 350
    AEKSPEERKR AVLDCYARWW GPKALSPRIF LEKSWKEEEY SRGCYLGYTS 400
    PGTLYQCGEH LRAPVGRIHW AGTETASVWI GYMEGALESG FRVSKEIKDK 450
    LLNSKL 456
    Length:456
    Mass (Da):51,259
    Last modified:May 24, 2005 - v1
    Checksum:iE97522D45FFE9F43
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000115 Genomic DNA. Translation: EAL63176.1.
    RefSeqiXP_636677.1. XM_631585.1.

    Genome annotation databases

    EnsemblProtistsiDDB0231707; DDB0231707; DDB_G0288541.
    GeneIDi8626677.
    KEGGiddi:DDB_G0288541.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000115 Genomic DNA. Translation: EAL63176.1 .
    RefSeqi XP_636677.1. XM_631585.1.

    3D structure databases

    ProteinModelPortali Q54IT3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 44689.DDB_0231707.

    Proteomic databases

    PRIDEi Q54IT3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi DDB0231707 ; DDB0231707 ; DDB_G0288541 .
    GeneIDi 8626677.
    KEGGi ddi:DDB_G0288541.

    Organism-specific databases

    dictyBasei DDB_G0288541. maoA.

    Phylogenomic databases

    eggNOGi COG1231.
    KOi K00274.
    OMAi REVLCAM.
    PhylomeDBi Q54IT3.

    Family and domain databases

    InterProi IPR002937. Amino_oxidase.
    IPR001613. Flavin_amine_oxidase.
    [Graphical view ]
    Pfami PF01593. Amino_oxidase. 1 hit.
    [Graphical view ]
    PRINTSi PR00757. AMINEOXDASEF.
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the social amoeba Dictyostelium discoideum."
      Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
      , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
      Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX4.

    Entry informationi

    Entry nameiAOFA_DICDI
    AccessioniPrimary (citable) accession number: Q54IT3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 8, 2008
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Dictyostelium discoideum
      Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3