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Q54I82 (CDD_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cytidine deaminase

EC=3.5.4.5
Alternative name(s):
Cytidine aminohydrolase
Gene names
Name:cda
ORF Names:DDB_G0288933
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length147 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis By similarity.

Catalytic activity

Cytidine + H2O = uridine + NH3.

2'deoxycytidine + H2O = 2'-deoxyuridine + NH3.

Cofactor

Zinc By similarity.

Sequence similarities

Belongs to the cytidine and deoxycytidylate deaminase family.

Contains 1 CMP/dCMP deaminase zinc-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 147147Probable cytidine deaminase
PRO_0000328079

Regions

Domain4 – 108105CMP/dCMP deaminase zinc-binding
Region45 – 517Substrate binding By similarity

Sites

Active site581Proton donor By similarity
Metal binding561Zinc; catalytic By similarity
Metal binding901Zinc; catalytic By similarity
Metal binding931Zinc; catalytic By similarity

Sequences

Sequence LengthMass (Da)Tools
Q54I82 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 09C5F427AB1ADD1F

FASTA14716,263
        10         20         30         40         50         60 
MNQEELEKCI DAAQNSQQYA HCPYSHFRIG AALLTSCGKI FTGVNVENSS YGLTICAERT 

        70         80         90        100        110        120 
AYTKAVSEGY KSFKGIVVAS DLKDRFITPC GACRQFGVEF GDFEVVCVKP DRSTFKSSTH 

       130        140 
KLLPGLFSQE DLIAKAEQDE RECKAQN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000126 Genomic DNA. Translation: EAL62990.1.

3D structure databases

ProteinModelPortalQ54I82.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDB_0230205.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0230205; DDB0230205; DDB_G0288933.
KEGGddi:DDB_G0288933.

Organism-specific databases

dictyBaseDDB_G0288933. cda.

Phylogenomic databases

eggNOGCOG0295.
KOK01489.
OMADERECKA.
PhylomeDBQ54I82.
ProtClustDBCLSZ2429832.

Family and domain databases

InterProIPR002125. CMP_dCMP_Zn-bd.
IPR006262. Cyt_deam_tetra.
IPR016193. Cytidine_deaminase-like.
[Graphical view]
PfamPF00383. dCMP_cyt_deam_1. 1 hit.
[Graphical view]
SUPFAMSSF53927. SSF53927. 1 hit.
TIGRFAMsTIGR01354. cyt_deam_tetra. 1 hit.
ProtoNetSearch...

Other

PROQ54I82.

Entry information

Entry nameCDD_DICDI
AccessionPrimary (citable) accession number: Q54I82
Entry history
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: April 16, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase