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Protein

Probable valine--tRNA ligase, mitochondrial

Gene

valS2

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei609ATPBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable valine--tRNA ligase, mitochondrial (EC:6.1.1.9)
Alternative name(s):
Valyl-tRNA synthetase
Short name:
ValRS
Gene namesi
Name:valS2
ORF Names:DDB_G0288939
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 5, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0288939 valS2

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 20MitochondrionSequence analysisAdd BLAST20
ChainiPRO_000032776121 – 1051Probable valine--tRNA ligase, mitochondrialAdd BLAST1031

Proteomic databases

PaxDbiQ54I78
PRIDEiQ54I78

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0304686

Structurei

3D structure databases

ProteinModelPortaliQ54I78
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili972 – 1019Sequence analysisAdd BLAST48

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi71 – 81"HIGH" regionBy similarityAdd BLAST11
Motifi606 – 610"KMSKS" regionBy similarity5

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi721 – 725Poly-Asn5
Compositional biasi946 – 958Poly-AsnAdd BLAST13

Sequence similaritiesi

Keywords - Domaini

Coiled coil, Transit peptide

Phylogenomic databases

eggNOGiKOG0432 Eukaryota
COG0525 LUCA
InParanoidiQ54I78
KOiK01873
OMAiRQWYIRN
PhylomeDBiQ54I78

Family and domain databases

CDDicd07962 Anticodon_Ia_Val, 1 hit
HAMAPiMF_02004 Val_tRNA_synth_type1, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR002300 aa-tRNA-synth_Ia
IPR033705 Anticodon_Ia_Val
IPR013155 M/V/L/I-tRNA-synth_anticd-bd
IPR009080 tRNAsynth_Ia_anticodon-bd
IPR009008 Val/Leu/Ile-tRNA-synth_edit
IPR002303 Valyl-tRNA_ligase
PfamiView protein in Pfam
PF08264 Anticodon_1, 1 hit
PF00133 tRNA-synt_1, 1 hit
PRINTSiPR00986 TRNASYNTHVAL
SUPFAMiSSF47323 SSF47323, 1 hit
SSF50677 SSF50677, 1 hit
TIGRFAMsiTIGR00422 valS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q54I78-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKLLFLSKK SSTSNLYRFY SRAPINESSI KSSFDPKVVE EFKYKYWQDS
60 70 80 90 100
GLFKPKSNNG GEKFSMVLPP PNVTGSLHIG HSLTTTIQDS LIRYNRMMGK
110 120 130 140 150
EVLWVPGLDH SGIATQVAVE KELQVKQGKT RFDLGREKFL EQVFQWTDQY
160 170 180 190 200
SSNINNQLKI TGSSLDWSRS VFTLDEQRND AVQTAFIRMF EMGLIYRSTR
210 220 230 240 250
LVNWCPYLQS VISDIEVDHK VIEKPTMLKL KSRKKSVEVG AIHNIAYMME
260 270 280 290 300
DPMLAPLIVS TTRPETIFGD TGLAIHPLDE RYKDYHGKFA IHPFNHERIP
310 320 330 340 350
IVLDDILVNR EMGTGVVKIT PAHDFNDYQC GQRHSLPIVN ILNSNGTLNE
360 370 380 390 400
NSTAEFEGVD RLDARSMVIE KLEQMGLYRE KLAHPQTLSI CSRSGDLLEP
410 420 430 440 450
VLKPQWYVKC KDMADKSIEF VESGEIKIIP ESFRADWSRW LTNIQDWCIS
460 470 480 490 500
RQLWWGNPIP AYRVIMIDKV TNEDLDIHLT ETERLKQEKW VVGKNEKEAR
510 520 530 540 550
ENVFKTYGIA NAGEYRLEKD QDVLDTWFSS GLFPISSMGW PTATKNSDND
560 570 580 590 600
NDFSRFLPLD VMETGSDILF FWVARMVMMC STLNNGEVPF KTILLHPMIR
610 620 630 640 650
DSQGRKMSKS LGNVIDPLHV INGISLQDLK ENLSKSNLSQ QEKVTATKGL
660 670 680 690 700
EKEFPQGIPQ CGTDSLRFSL AQYPINGKDI NLDISKIIGN RLFCNKLWNA
710 720 730 740 750
SKFVFNYLVN LNNLSINLYY NNNNNEKDQQ QPFNYLESTT LIDKWILLKL
760 770 780 790 800
SKLVEIVNES YKSNNLSIAA QSLYSFFQYD FCDIYIECIK ADLSKPILSK
810 820 830 840 850
QNEHSSLVLA SVLDSYLRML HPFMPFITED LWQRLPKSKQ QLEIANSIEI
860 870 880 890 900
DDSLSIMISD YPNPSYKYHQ LFKNQEIEIE KQVNLFLDTL KLIRSQKVSL
910 920 930 940 950
GINEKTKLII KLQIIGDDQI LIKSSFNQLK DSFEKLLNSN LIIDENNNND
960 970 980 990 1000
NNNNNDNNDL TNISINKFTI SKELQISIEF DKEINNQLNQ KLINPNQSND
1010 1020 1030 1040 1050
KKILKLENFI KQLQDEIDNP DFKQRVPEKV QNIKIEKLNQ YKIELKEIYK

K
Length:1,051
Mass (Da):121,425
Last modified:January 19, 2010 - v2
Checksum:i9631791BD20CB26C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000126 Genomic DNA Translation: EAL62993.2
RefSeqiXP_636501.2, XM_631409.2

Genome annotation databases

EnsemblProtistsiEAL62993; EAL62993; DDB_G0288939
GeneIDi8626884
KEGGiddi:DDB_G0288939

Similar proteinsi

Entry informationi

Entry nameiSYVM_DICDI
AccessioniPrimary (citable) accession number: Q54I78
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: January 19, 2010
Last modified: May 23, 2018
This is version 94 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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