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Q54GA9

- MGST_DICDI

UniProt

Q54GA9 - MGST_DICDI

Protein

Probable microsomal glutathione S-transferase

Gene

mgst

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
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    Functioni

    May perform the conjugation of reduced glutathione to electrophiles.By similarity

    Catalytic activityi

    RX + glutathione = HX + R-S-glutathione.

    GO - Molecular functioni

    1. glutathione peroxidase activity Source: RefGenome
    2. glutathione transferase activity Source: RefGenome

    GO - Biological processi

    1. metabolic process Source: GOC
    2. oxidation-reduction process Source: GOC

    Keywords - Molecular functioni

    Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable microsomal glutathione S-transferase (EC:2.5.1.18)
    Gene namesi
    Name:mgst
    ORF Names:DDB_G0290291
    OrganismiDictyostelium discoideum (Slime mold)
    Taxonomic identifieri44689 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
    ProteomesiUP000002195: Chromosome 5, UP000002195: Unassembled WGS sequence

    Organism-specific databases

    dictyBaseiDDB_G0290291.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum Source: RefGenome
    2. integral component of membrane Source: UniProtKB-KW
    3. nuclear envelope Source: RefGenome

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 149149Probable microsomal glutathione S-transferasePRO_0000331235Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi44689.DDB_0231516.

    Structurei

    3D structure databases

    ProteinModelPortaliQ54GA9.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei7 – 2721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei123 – 14321HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the MAPEG family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG77136.
    KOiK00799.
    OMAiEYQNTSE.
    PhylomeDBiQ54GA9.

    Family and domain databases

    Gene3Di1.20.120.550. 1 hit.
    InterProiIPR023352. MAPEG-like_dom.
    IPR001129. Membr-assoc_MAPEG.
    [Graphical view]
    PfamiPF01124. MAPEG. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q54GA9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPFDTKSIFP DFIVFPSAIS TIAIGLWSVQ AYKLGEARKR YNVKAPHVQG    50
    DPEFERIAHE YQNTSEALGA IIPATFMFSY YISPKCSLLL GGTWLVSKML 100
    NCCSYCCKKE KENDCAKNVH TCLSHISFFA LLGGSAFGIG SSLYNRYKL 149
    Length:149
    Mass (Da):16,626
    Last modified:May 24, 2005 - v1
    Checksum:iFB822FF2A2C7818A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000162 Genomic DNA. Translation: EAL62272.1.
    RefSeqiXP_635774.1. XM_630682.1.

    Genome annotation databases

    EnsemblProtistsiDDB0231516; DDB0231516; DDB_G0290291.
    GeneIDi8627578.
    KEGGiddi:DDB_G0290291.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAFI02000162 Genomic DNA. Translation: EAL62272.1 .
    RefSeqi XP_635774.1. XM_630682.1.

    3D structure databases

    ProteinModelPortali Q54GA9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 44689.DDB_0231516.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi DDB0231516 ; DDB0231516 ; DDB_G0290291 .
    GeneIDi 8627578.
    KEGGi ddi:DDB_G0290291.

    Organism-specific databases

    dictyBasei DDB_G0290291.

    Phylogenomic databases

    eggNOGi NOG77136.
    KOi K00799.
    OMAi EYQNTSE.
    PhylomeDBi Q54GA9.

    Miscellaneous databases

    PROi Q54GA9.

    Family and domain databases

    Gene3Di 1.20.120.550. 1 hit.
    InterProi IPR023352. MAPEG-like_dom.
    IPR001129. Membr-assoc_MAPEG.
    [Graphical view ]
    Pfami PF01124. MAPEG. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the social amoeba Dictyostelium discoideum."
      Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
      , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
      Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX4.

    Entry informationi

    Entry nameiMGST_DICDI
    AccessioniPrimary (citable) accession number: Q54GA9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 29, 2008
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Dictyostelium discoideum
      Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3