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Q54GA9

- MGST_DICDI

UniProt

Q54GA9 - MGST_DICDI

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Protein

Probable microsomal glutathione S-transferase

Gene

mgst

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

May perform the conjugation of reduced glutathione to electrophiles.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

  1. glutathione peroxidase activity Source: RefGenome
  2. glutathione transferase activity Source: RefGenome

GO - Biological processi

  1. metabolic process Source: GOC
  2. oxidation-reduction process Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable microsomal glutathione S-transferase (EC:2.5.1.18)
Gene namesi
Name:mgst
ORF Names:DDB_G0290291
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 5, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0290291.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei7 – 2721HelicalSequence AnalysisAdd
BLAST
Transmembranei123 – 14321HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. endoplasmic reticulum Source: RefGenome
  2. integral component of membrane Source: UniProtKB-KW
  3. nuclear envelope Source: RefGenome
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 149149Probable microsomal glutathione S-transferasePRO_0000331235Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB_0231516.

Structurei

3D structure databases

ProteinModelPortaliQ54GA9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MAPEG family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG77136.
InParanoidiQ54GA9.
KOiK00799.
OMAiEYQNTSE.
PhylomeDBiQ54GA9.

Family and domain databases

Gene3Di1.20.120.550. 1 hit.
InterProiIPR023352. MAPEG-like_dom.
IPR001129. Membr-assoc_MAPEG.
[Graphical view]
PfamiPF01124. MAPEG. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q54GA9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPFDTKSIFP DFIVFPSAIS TIAIGLWSVQ AYKLGEARKR YNVKAPHVQG
60 70 80 90 100
DPEFERIAHE YQNTSEALGA IIPATFMFSY YISPKCSLLL GGTWLVSKML
110 120 130 140
NCCSYCCKKE KENDCAKNVH TCLSHISFFA LLGGSAFGIG SSLYNRYKL
Length:149
Mass (Da):16,626
Last modified:May 24, 2005 - v1
Checksum:iFB822FF2A2C7818A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000162 Genomic DNA. Translation: EAL62272.1.
RefSeqiXP_635774.1. XM_630682.1.

Genome annotation databases

EnsemblProtistsiDDB0231516; DDB0231516; DDB_G0290291.
GeneIDi8627578.
KEGGiddi:DDB_G0290291.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000162 Genomic DNA. Translation: EAL62272.1 .
RefSeqi XP_635774.1. XM_630682.1.

3D structure databases

ProteinModelPortali Q54GA9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 44689.DDB_0231516.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0231516 ; DDB0231516 ; DDB_G0290291 .
GeneIDi 8627578.
KEGGi ddi:DDB_G0290291.

Organism-specific databases

dictyBasei DDB_G0290291.

Phylogenomic databases

eggNOGi NOG77136.
InParanoidi Q54GA9.
KOi K00799.
OMAi EYQNTSE.
PhylomeDBi Q54GA9.

Miscellaneous databases

PROi Q54GA9.

Family and domain databases

Gene3Di 1.20.120.550. 1 hit.
InterProi IPR023352. MAPEG-like_dom.
IPR001129. Membr-assoc_MAPEG.
[Graphical view ]
Pfami PF01124. MAPEG. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiMGST_DICDI
AccessioniPrimary (citable) accession number: Q54GA9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: May 24, 2005
Last modified: October 29, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3