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Protein

Probable tyrosine-protein kinase DDB_G0290471

Gene

DDB_G0290471

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei78ATPPROSITE-ProRule annotation1
Active sitei175Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi57 – 65ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase, Tyrosine-protein kinase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tyrosine-protein kinase DDB_G0290471 (EC:2.7.10.2)
Gene namesi
ORF Names:DDB_G0290471
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 5, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0290471

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003551451 – 352Probable tyrosine-protein kinase DDB_G0290471Add BLAST352

Proteomic databases

PaxDbiQ54G28

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0229850

Structurei

3D structure databases

ProteinModelPortaliQ54G28
SMRiQ54G28
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 333Protein kinasePROSITE-ProRule annotationAdd BLAST283

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi16 – 24Poly-Asn9

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0192 Eukaryota
COG0515 LUCA
InParanoidiQ54G28
OMAiGDFMVTM
PhylomeDBiQ54G28

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008266 Tyr_kinase_AS
PfamiView protein in Pfam
PF07714 Pkinase_Tyr, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00109 PROTEIN_KINASE_TYR, 1 hit

Sequencei

Sequence statusi: Complete.

Q54G28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEIVINNISG LNNSFNNNNN SNNNDENEIN FNLIKESIVN FKLWDINNKQ
60 70 80 90 100
IEYVCRLGSG SLCRVYKGRL NGKPVAIKVF SPIRFEEFKT EFLMMQSLRS
110 120 130 140 150
SPFLISFYGV SIVEEPQKQC YCIITEFCSR DSLYHIMTDR LIEIGWNRFF
160 170 180 190 200
QFSMQIILGL QSLHNRKPKP IVHRDVTSLN ILVNEDWECK ISNFSASRFN
210 220 230 240 250
CLNTEYINSN NQNKSFAFCS PESSDFQDID DDYTSLSSSI TSKSDIYSFG
260 270 280 290 300
IIMFELISRI INGEYSHPFS EFKDIKNDFQ LLLSSKNGLR PSLPNICPEP
310 320 330 340 350
LEKLYKQCVD QSPLNRPSCE EVIISLNQIR SFYLLPQTKK SWDNLVLKNK

CK
Length:352
Mass (Da):40,829
Last modified:May 24, 2005 - v1
Checksum:i49481817D4103A3D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000163 Genomic DNA Translation: EAL62251.1
RefSeqiXP_635744.1, XM_630652.1

Genome annotation databases

EnsemblProtistsiEAL62251; EAL62251; DDB_G0290471
GeneIDi8627663
KEGGiddi:DDB_G0290471

Entry informationi

Entry nameiYTYK1_DICDI
AccessioniPrimary (citable) accession number: Q54G28
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: May 24, 2005
Last modified: March 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health