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Q54G28 (YTYK1_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable tyrosine-protein kinase DDB_G0290471

EC=2.7.10.2
Gene names
ORF Names:DDB_G0290471
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

Sequence similarities

Belongs to the protein kinase superfamily. TKL Tyr protein kinase family.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 352352Probable tyrosine-protein kinase DDB_G0290471
PRO_0000355145

Regions

Domain51 – 333283Protein kinase
Nucleotide binding57 – 659ATP By similarity
Compositional bias16 – 249Poly-Asn

Sites

Active site1751Proton acceptor By similarity
Binding site781ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q54G28 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 49481817D4103A3D

FASTA35240,829
        10         20         30         40         50         60 
MEIVINNISG LNNSFNNNNN SNNNDENEIN FNLIKESIVN FKLWDINNKQ IEYVCRLGSG 

        70         80         90        100        110        120 
SLCRVYKGRL NGKPVAIKVF SPIRFEEFKT EFLMMQSLRS SPFLISFYGV SIVEEPQKQC 

       130        140        150        160        170        180 
YCIITEFCSR DSLYHIMTDR LIEIGWNRFF QFSMQIILGL QSLHNRKPKP IVHRDVTSLN 

       190        200        210        220        230        240 
ILVNEDWECK ISNFSASRFN CLNTEYINSN NQNKSFAFCS PESSDFQDID DDYTSLSSSI 

       250        260        270        280        290        300 
TSKSDIYSFG IIMFELISRI INGEYSHPFS EFKDIKNDFQ LLLSSKNGLR PSLPNICPEP 

       310        320        330        340        350 
LEKLYKQCVD QSPLNRPSCE EVIISLNQIR SFYLLPQTKK SWDNLVLKNK CK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000163 Genomic DNA. Translation: EAL62251.1.
RefSeqXP_635744.1. XM_630652.1.

3D structure databases

ProteinModelPortalQ54G28.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0229850; DDB0229850; DDB_G0290471.
GeneID8627663.
KEGGddi:DDB_G0290471.

Organism-specific databases

dictyBaseDDB_G0290471.

Phylogenomic databases

eggNOGKOG0192.
OMAINEYNIM.
PhylomeDBQ54G28.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
[Graphical view]
PfamPF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYTYK1_DICDI
AccessionPrimary (citable) accession number: Q54G28
Entry history
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: May 24, 2005
Last modified: May 14, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase