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Q54F73 (CCS_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable copper chaperone for superoxide dismutase
Alternative name(s):
Superoxide dismutase copper chaperone
Gene names
Name:ccs
Synonyms:ccsA
ORF Names:DDB_G0291031
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length316 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Delivers copper to copper zinc superoxide dismutases By similarity.

Cofactor

Binds 2 copper ions per subunit By similarity.

Subunit structure

Homodimer, and heterodimer with SOD1 By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.

Contains 1 HMA domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 316316Probable copper chaperone for superoxide dismutase
PRO_0000329400

Regions

Domain8 – 7265HMA
Region99 – 298200Superoxide dismutase-like
Compositional bias78 – 847Poly-Thr
Compositional bias182 – 21029Poly-Asn
Compositional bias268 – 2758Poly-Asn

Sites

Metal binding181Copper 1 Potential
Metal binding211Copper 1 Potential
Metal binding3081Copper 2 By similarity
Metal binding3101Copper 2 By similarity

Amino acid modifications

Disulfide bond169 ↔ 291 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q54F73 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: C167C77135B10589

FASTA31634,468
        10         20         30         40         50         60 
MDDKNLEIKV ELNVDISCQS CVDSISKELR EKLENTKLVE HDIPEQRIVL QGTDLTQDIL 

        70         80         90        100        110        120 
ETIKNTGRNA TICGLSSTTT TTSTSPSSST CHKKQETVSG SAVCSLGLIE NWQKGCGGSG 

       130        140        150        160        170        180 
GVGSKGVYGV IRLLRASTTK TLFEGRITGL KPGKHSLVVH EFGNLMNGCD DLGEPFISNV 

       190        200        210        220        230        240 
ENNNNNNNNN NNNNNNNNNN NNNNNNNNKN INKCKEILNK IIGTSDVKQD GKAEFRVLSD 

       250        260        270        280        290        300 
KYDFWDLIGR SIVLHSQDSK YSPIEDLNNN NNNKNIVNSE SDKILGERVA CGIISRAASI 

       310 
GQNHKKVCPC DGTTAI 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000174 Genomic DNA. Translation: EAL61946.1.

3D structure databases

ProteinModelPortalQ54F73.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDBDRAFT_0189222.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0238038; DDB0238038; DDB_G0291031.
KEGGddi:DDB_G0291031.

Organism-specific databases

dictyBaseDDB_G0291031. ccs.

Phylogenomic databases

eggNOGNOG327209.
OMAIVLHSQD.
PhylomeDBQ54F73.

Family and domain databases

Gene3D2.60.40.200. 2 hits.
InterProIPR006121. HeavyMe-assoc_HMA.
IPR024134. SOD_Cu/Zn_/chaperone.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PANTHERPTHR10003. PTHR10003. 1 hit.
PfamPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMSSF49329. SSF49329. 2 hits.
SSF55008. SSF55008. 1 hit.
ProtoNetSearch...

Other

PROQ54F73.

Entry information

Entry nameCCS_DICDI
AccessionPrimary (citable) accession number: Q54F73
Entry history
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: April 16, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase