Q54F40 (Y1133_DICDI) Reviewed, UniProtKB/Swiss-Prot
Last modified
September 21, 2011.
Version 48.
History...
Clusters with 
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Probable protein kinase DDB_G0291133 EC=2.7.11.1 | ||
| Gene names |
| ||
| Organism | Dictyostelium discoideum (Slime mold) | ||
| Taxonomic identifier | 44689 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium |
Protein attributes
| Sequence length | 778 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | ATP + a protein = ADP + a phosphoprotein. |
| Sequence similarities | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily. Contains 1 protein kinase domain. |
Ontologies
| Keywords | |
|---|---|
| Ligand | ATP-binding Magnesium Metal-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | regulation of cell cycle Inferred from sequence or structural similarity. Source: dictyBase |
| Cellular component | nucleus Inferred from sequence or structural similarity. Source: dictyBase |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW metal ion bindingInferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activityInferred from electronic annotation. Source: InterPro protein tyrosine kinase activityInferred from sequence or structural similarity. Source: dictyBase |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 778 | 778 | Probable protein kinase DDB_G0291133 | PRO_0000362042 | |||||
Regions | |||||||||
| Domain | 177 – 462 | 286 | Protein kinase | ||||||
| Nucleotide binding | 183 – 191 | 9 | ATP By similarity | ||||||
| Compositional bias | 132 – 141 | 10 | Poly-Asn | ||||||
| Compositional bias | 332 – 338 | 7 | Poly-Asn | ||||||
| Compositional bias | 481 – 488 | 8 | Poly-Asn | ||||||
| Compositional bias | 491 – 496 | 6 | Poly-Asn | ||||||
| Compositional bias | 508 – 516 | 9 | Poly-Asn | ||||||
| Compositional bias | 571 – 575 | 5 | Poly-Ser | ||||||
| Compositional bias | 583 – 589 | 7 | Poly-Asp | ||||||
| Compositional bias | 631 – 635 | 5 | Poly-Ser | ||||||
| Compositional bias | 671 – 693 | 23 | Poly-Asn | ||||||
Sites | |||||||||
| Active site | 303 | 1 | Proton acceptor By similarity | ||||||
| Metal binding | 308 | 1 | Magnesium; via carbonyl oxygen By similarity | ||||||
| Metal binding | 321 | 1 | Magnesium; via carbonyl oxygen By similarity | ||||||
| Binding site | 206 | 1 | ATP By similarity | ||||||
Sequences
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References
| [1] | "The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.  Kuspa A.Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AAFI02000175 Genomic DNA. Translation: EAL61850.1. |
| RefSeq | XP_635350.1. XM_630258.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1ZYD based on UniProtKB P15442. |
| ProteinModelPortal | Q54F40. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblProtists | DDB0229384; DDB0229384; DDB_G0291133. |
| GeneID | 8627998. |
| KEGG | ddi:DDB_G0291133. |
Organism-specific databases | |
| dictyBase | DDB_G0291133. |
Phylogenomic databases | |
| eggNOG | KOG0601. |
| GeneTree | EPrGT00050000002069. |
| InParanoid | Q54F40. |
| PhylomeDB | Q54F40. |
Family and domain databases | |
| InterPro | IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_kinase-like_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view] |
| Pfam | PF00069. Pkinase. 1 hit. [Graphical view] |
| SUPFAM | SSF56112. Kinase_like. 1 hit. |
| PROSITE | PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | Y1133_DICDI | ||||||||
| Accession | Primary (citable) accession number: Q54F40 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
Relevant documents
| Dictyostelium discoideum Dictyostelium discoideum: entries, gene names and cross-references to dictyBase |
| SIMILARITY comments Index of protein domains and families |