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Protein

Iron-sulfur protein NUBPL

Gene

nubpl

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). May deliver of one or more Fe-S clusters to complex I subunits (By similarity).By similarity

Cofactori

[4Fe-4S] clusterBy similarityNote: Binds 1 [4Fe-4S] cluster.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi65 – 728ATPSequence analysis

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-binding, Iron, Iron-sulfur, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DDI-6799198. Complex I biogenesis.

Names & Taxonomyi

Protein namesi
Recommended name:
Iron-sulfur protein NUBPL
Alternative name(s):
Nucleotide-binding protein-like
Gene namesi
Name:nubpl
ORF Names:DDB_G0291193
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 5, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0291193. nubpl.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 323Iron-sulfur protein NUBPLPRO_0000327673
Transit peptidei1 – ?MitochondrionBy similarity

Proteomic databases

PaxDbiQ54F15.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0232425.

Structurei

3D structure databases

ProteinModelPortaliQ54F15.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG3022. Eukaryota.
COG0489. LUCA.
InParanoidiQ54F15.
KOiK03593.
OMAiTMPFVWL.
PhylomeDBiQ54F15.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_02040. Mrp_NBP35.
InterProiIPR019591. Mrp/NBP35_ATP-bd.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR23264. PTHR23264. 1 hit.
PfamiPF10609. ParA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q54F15-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFKKLITTPF FSPNKQFITF QLESGKRNYF SNNKIQLHGG SGHRQPQVTK
60 70 80 90 100
VAIEGIKNII AVSSAKGGVG KSTCAVNIAL GLSSHNLSVG LLDVDVFGPS
110 120 130 140 150
IPLMMDLKNH EKPFTNELNQ MIPLQNYGIK CMSMGFLVNE DDPIIWRGPM
160 170 180 190 200
VGSALEKLLR QTDWGHLDVL VCDLPPGTGD AILTMCQRVP LTGAVIVSTP
210 220 230 240 250
QDVALADVVR GVNMFKKVEV PILGLVENMS YFNCPHCNES THIFGNEGAK
260 270 280 290 300
NTAKKMGINF LGDVPIHLQI RETSDSGKPI TVTQPDSPQA KNYKDISKEI
310 320
IKQLEIINND ENKDNKEPNI IIT
Length:323
Mass (Da):35,479
Last modified:May 24, 2005 - v1
Checksum:i1EA0BAE389554B1E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000175 Genomic DNA. Translation: EAL61880.1.
RefSeqiXP_635375.1. XM_630283.1.

Genome annotation databases

EnsemblProtistsiDDB0232425; DDB0232425; DDB_G0291193.
GeneIDi8628023.
KEGGiddi:DDB_G0291193.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000175 Genomic DNA. Translation: EAL61880.1.
RefSeqiXP_635375.1. XM_630283.1.

3D structure databases

ProteinModelPortaliQ54F15.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0232425.

Proteomic databases

PaxDbiQ54F15.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiDDB0232425; DDB0232425; DDB_G0291193.
GeneIDi8628023.
KEGGiddi:DDB_G0291193.

Organism-specific databases

dictyBaseiDDB_G0291193. nubpl.

Phylogenomic databases

eggNOGiKOG3022. Eukaryota.
COG0489. LUCA.
InParanoidiQ54F15.
KOiK03593.
OMAiTMPFVWL.
PhylomeDBiQ54F15.

Enzyme and pathway databases

ReactomeiR-DDI-6799198. Complex I biogenesis.

Miscellaneous databases

PROiQ54F15.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_02040. Mrp_NBP35.
InterProiIPR019591. Mrp/NBP35_ATP-bd.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR23264. PTHR23264. 1 hit.
PfamiPF10609. ParA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiNUBPL_DICDI
AccessioniPrimary (citable) accession number: Q54F15
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: February 17, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.