Q54ET6 (ABPF_DICDI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Actin-binding protein F

Gene names

Name:	abpF
Synonyms:	kenN
ORF Names:	DDB_0230207

Organism

Dictyostelium discoideum (Slime mold)

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	2364 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Interacts with actin.
Subcellular location	Nucleus. Cytoplasm › cytoskeleton. Note: localizes at the centrosome. Ref.2

Ontologies

Keywords
Cellular component	Cytoplasm Cytoskeleton Nucleus
Domain	Coiled coil
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW cytoskeleton Inferred from electronic annotation. Source: UniProtKB-SubCell nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 2364	2364	Actin-binding protein F		PRO_0000388373
Regions
	Coiled coil	1960 – 2017	58	Potential
	Coiled coil	2129 – 2173	45	Potential
	Compositional bias	152 – 158	7	Poly-Ser
	Compositional bias	1412 – 1420	9	Poly-Asn
	Compositional bias	1963 – 2014	52	Lys-rich
	Compositional bias	2028 – 2035	8	Poly-Thr
	Compositional bias	2038 – 2047	10	Poly-Thr

Sequences

	Sequence		Length	Mass (Da)
	Q54ET6 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 64C12F4868180943	FASTA	2,364	269,778
	10 20 30 40 50 60 MTVSNNKKFE ENYVLASDIE EKEKLLGTLI GGSPQYFYYN VIHLLNVDPT LSDSKNREKY 70 80 90 100 110 120 QKLMKDWSPE SKPIPVTPYG GNNNYESTQQ YKSVDLRQKL LSFRQDNVNP SALANNVNDM 130 140 150 160 170 180 FEELRYLLSL TFSYTQTTHQ TSPTTETTTT PSSSSSSSHD DKSESTLDES LVNKKTVIES 190 200 210 220 230 240 IINQYPYKVD YISPNSFEYV LNNFTLPESA EKSIVQKLKY PIVPNDKLQQ LLSHHKGSFG 250 260 270 280 290 300 SLKIHENLTL EQMEKHIEKN PEHLDSAYVK LYLEKLLPTN ELHDWETLKP VQEQFYQSAS 310 320 330 340 350 360 KFVSNLPTSL NTFKLLIYHH YIKFQISDNK YDQSIIEKYF QLPRDTYYYV EPDRLKSNPQ 370 380 390 400 410 420 LSKFNDSFNG LKSVSQDDDE KLISFLLKKL FLKENSIKSY QSYFRPNYLN LILAESKLLS 430 440 450 460 470 480 NDSSPEKWIE MIDNHTKVQE LKDRVDIEFL PTNREYYHPD DDVVIECAIK NVNTLLVKVF 490 500 510 520 530 540 EISTFNYYKS ENKKIDSNIN LDGLIASQEL SFDYSEQAPI EKVEKKFDFP NLKGKRGIFV 550 560 570 580 590 600 IEFIGNGKSS RSMIQKGDLH FIVETSPIGQ VIKIIDQDSI KVQKSSVYID GNAYNSNDDG 610 620 630 640 650 660 DIKIPFSSST SQKSIILMAK IGDSDVFASL KKFTHQSEHY SLSGGIFVEN SSLLQNEKAP 670 680 690 700 710 720 IVVRVKLFLG DTQISNNYLE EPSLTITSSD NSESPVVNSK EIKPFALFDN KESVYQYKVQ 730 740 750 760 770 780 EGLNSLTVRF EAKVRALSRN NNQETLSFES TFQVNTINQT DQISEFYLER CLAKDGCSLG 790 800 810 820 830 840 YQLCHLGKGG DPFSHLDVSM DFQHWLTSER IYTTLKTDKN GKIHLGSLAD IEQLNVNGSY 850 860 870 880 890 900 ATFNFPIKRQ QQFTYPSQIN IKLGETIRLP YLGNEKSVSH SQINFFQLGG VDDRNFVVHD 910 920 930 940 950 960 LLKKSVTIEN KNELLINGLG VGRYLLILAG SIQSSNTVEI LIDVVDGQFR EGYLVGPSRI 970 980 990 1000 1010 1020 VSYNESNVKS LFFDTNIDTK HNQLQVKFKN HSPSTRVHVF SSYFEPTNSL NSSLSLSRGT 1030 1040 1050 1060 1070 1080 SQSYQEYSVK PKSLYFNGRS LGDEVNYILN RKTSKKLLPG NSLKKPSLLV QPWSIGKTTN 1090 1100 1110 1120 1130 1140 STNTLKQASK YNESEVKDEK SMRNRQVEKR RVSSTNRSPF LEFLSHPSIL LLNLEPSSTD 1150 1160 1170 1180 1190 1200 GIVNIDLSQL VEAGSTIHIH AVDNDSIFTK EIVISDPSSS SSINHFKDTK LVRPLDSSLH 1210 1220 1230 1240 1250 1260 YKEEKLITTV EPNSPFEILN VNSSKYTVYD SLDKVLSLMK TLNKSYLQDF SFIAEWESLS 1270 1280 1290 1300 1310 1320 FEKKKEKFSK FTCHELNFFI YKKDKEFFDQ VVLPLVQTKG YKTFIDHYLC ADRKKLEIFV 1330 1340 1350 1360 1370 1380 IDSNRFNTLN ALEMVLLGEL FPEHSDSISN LLKQKVGFSP ISPSQYDTNF KIALNQLDTD 1390 1400 1410 1420 1430 1440 IESLKSGDDD LYDDGSNLEP MSVGGGGGFG YNNNSNNNNN TTNSNSFGDA KRAPMKKKMV 1450 1460 1470 1480 1490 1500 NKESTSLMMD CAAPMMMMAS APCPAPGAVP MAALRSARLA SASPAPPAPI TRAYEAAQIY 1510 1520 1530 1540 1550 1560 QPIEKTEELA ETYYYKQLNP HSSLIPVNEF WLDYANHIKS QSKTPFVSKY IAFISSSFAE 1570 1580 1590 1600 1610 1620 SMMALSVLDF PFTVKDNTTQ VRPKNGKLSM KPTTPIVVFH QELVSGSIEK QSDILVTQHF 1630 1640 1650 1660 1670 1680 FDPQNQFTYI DGEQEELYIN DQFLVSKVYG AMVVIANLSS KQKKLDALLE IPKGSIAVGP 1690 1700 1710 1720 1730 1740 SPFVTRSKSV NLSAYSTTRL QYYFYFPEAG KFPHFPAHVS EKQNIIANVT PFTFSVVLKP 1750 1760 1770 1780 1790 1800 SIVNHLSWEY IANQGTLESI LEYLSKNNLY RVDFYHLYHR YTDKKVWDKV IELLKKLKFY 1810 1820 1830 1840 1850 1860 ESITWSFSIH HKNFVYLKDY LSEQIHSLSM KSIDAPSIYV DPFENNFIKF LEYSPLVNSR 1870 1880 1890 1900 1910 1920 THQIGDERKI LNNKLSNQYY EFCSLLSLKL NPSDTELLSL AYYLLLQDRF DESIKIMKRI 1930 1940 1950 1960 1970 1980 GKHPVSIPKL ISSSTTTDSK STHSSVISSS SSSNLSTTTD SSKDKKKLEK EEKQREKERK 1990 2000 2010 2020 2030 2040 QKEKEDKKRE KEELKKKEKE EKKKKEEEKK LKKKSGSEAT SPSVDPATPT TTTTTEATTT 2050 2060 2070 2080 2090 2100 TTTTTATSQE SIKPEKIASD DEHDDHHHDE HDEEDDDDEP LIDMSEFNQP SCLPEMKVQY 2110 2120 2130 2140 2150 2160 DYLLSYLDFF NPNPTVAAEN SKKYENYPVQ RWNSLFKDLR NKVDQVSNKD SVEIDYEKEI 2170 2180 2190 2200 2210 2220 DRERRQNKMA SNEPTFDISS ESNRTISVNY SNLVDITVSY YVMDIEHLFS TNPFVQQELG 2230 2240 2250 2260 2270 2280 HFLYVTPNKK ESFLLKDKSG TFNFKIPNEF ANSNVVIDVV SAQIHHNITV YSNNLAVYIT 2290 2300 2310 2320 2330 2340 EKVGQLRVVH KQKSQPISKT YIKVYSKNKN GSVEFFKDGY TDIAGYFDYS TVSSLDISNV 2350 2360 SKLSILVLSN QYGAVIKEAK PPGF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.
[2]	Niebling K.R. Thesis (1993), Standford University, United States Cited for: ACTIN-BINDING, SUBCELLULAR LOCATION.
[3]	Bienvenut W.V., Ura S., Insall R.H. Submitted (JUL-2009) to UniProtKB Cited for: PROTEIN SEQUENCE OF 364-372; 537-548; 850-862; 1040-1052 AND 1356-1371, MASS SPECTROMETRY. Strain: AX2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAFI02000177 Genomic DNA. Translation: EAL61598.1.
RefSeq	XP_635154.1. XM_630062.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	DDB0230207; DDB0230207; DDB_G0291229.
GeneID	8628100.
GenomeReviews	Gene locus abpF in contig CM000155_GR.
KEGG	ddi:DDB_G0291229.
Organism-specific databases
dictyBase	DDB_G0291229. abpF.
Phylogenomic databases
GeneTree	EPrGT00060000009930.
InParanoid	Q54ET6.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

ABPF_DICDI

Accession

Primary (citable) accession number: Q54ET6

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 3, 2009
Last sequence update:	May 24, 2005
Last modified:	September 21, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)