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Protein

Putative synaptobrevin homolog YKT6

Gene

ykt6

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport and in early/recycling endosome to TGN transport as part of a SNARE complex. Has a S-palmitoyl transferase activity (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processER-Golgi transport, Protein transport, Transport

Enzyme and pathway databases

ReactomeiR-DDI-204005 COPII-mediated vesicle transport
R-DDI-6807878 COPI-mediated anterograde transport
R-DDI-6811438 Intra-Golgi traffic

Names & Taxonomyi

Protein namesi
Recommended name:
Putative synaptobrevin homolog YKT6 (EC:2.3.1.-)
Alternative name(s):
Putative prenylated SNARE protein ykt6
Gene namesi
Name:ykt6
ORF Names:DDB_G0291656
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 6, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0291656 ykt6

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm, Cytoplasmic vesicle, Endosome, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003283141 – 199Putative synaptobrevin homolog YKT6Add BLAST199
PropeptideiPRO_0000396668200 – 202Removed in mature formBy similarity3

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi198S-palmitoyl cysteineBy similarity1
Modified residuei199Cysteine methyl esterBy similarity1
Lipidationi199S-farnesyl cysteineBy similarity1

Keywords - PTMi

Lipoprotein, Methylation, Palmitate, Prenylation

Proteomic databases

PaxDbiQ54ES8

Interactioni

Subunit structurei

May be found in 2 different SNARE complexes.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi44689.DDB0238214

Structurei

3D structure databases

ProteinModelPortaliQ54ES8
SMRiQ54ES8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 129LonginPROSITE-ProRule annotationAdd BLAST123
Domaini142 – 202v-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST61

Sequence similaritiesi

Belongs to the synaptobrevin family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG0861 Eukaryota
COG5143 LUCA
InParanoidiQ54ES8
KOiK08516
OMAiYPVRPAF
PhylomeDBiQ54ES8

Family and domain databases

InterProiView protein in InterPro
IPR011012 Longin-like_dom_sf
IPR010908 Longin_dom
IPR001388 Synaptobrevin
PfamiView protein in Pfam
PF00957 Synaptobrevin, 1 hit
SMARTiView protein in SMART
SM01270 Longin, 1 hit
SUPFAMiSSF64356 SSF64356, 1 hit
PROSITEiView protein in PROSITE
PS50859 LONGIN, 1 hit
PS50892 V_SNARE, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q54ES8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVYSIGLFK VVPGNKPVLL NIVYELSSFG FFQRGSVKEV SLFVSRETVG
60 70 80 90 100
RTNVGERVSM EHTQTQKVCH TTVDSKGLGC SVLTDSEYPG RVAHTLIRIC
110 120 130 140 150
LEEFYKVHPE SEWRGLQSDV ELQTPALDQL LLKYQNPETA DPMMNLQKNL
160 170 180 190 200
DETITIVKKT VEQLGQRGEK LDDLAAKSDD LSFQSKAFMN NAERMNKCCG

YV
Length:202
Mass (Da):22,771
Last modified:May 24, 2005 - v1
Checksum:iD31A9B37848DE5C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000177 Genomic DNA Translation: EAL61812.1
RefSeqiXP_635162.1, XM_630070.1

Genome annotation databases

EnsemblProtistsiEAL61812; EAL61812; DDB_G0291656
GeneIDi8628108
KEGGiddi:DDB_G0291656

Similar proteinsi

Entry informationi

Entry nameiYKT6_DICDI
AccessioniPrimary (citable) accession number: Q54ES8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: May 23, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health