Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable ribonuclease P/MRP protein subunit POP5

Gene

pop5

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP (By similarity).By similarity

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC

GO - Biological processi

  1. RNA phosphodiester bond hydrolysis Source: GOC
  2. RNA phosphodiester bond hydrolysis, endonucleolytic Source: GOC
  3. rRNA processing Source: dictyBase
  4. tRNA processing Source: dictyBase
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ribonuclease P/MRP protein subunit POP5 (EC:3.1.26.5)
Gene namesi
Name:pop5
ORF Names:DDB_G0291662
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195 Componentsi: Chromosome 6, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0291662. pop5.

Subcellular locationi

Nucleusnucleolus By similarity

GO - Cellular componenti

  1. nucleolar ribonuclease P complex Source: dictyBase
  2. ribonuclease MRP complex Source: dictyBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 171171Probable ribonuclease P/MRP protein subunit POP5PRO_0000327380Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi44689.DDBDRAFT_0219669.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1369.
InParanoidiQ54EP3.
KOiK03537.
OMAiFQFISNE.
PhylomeDBiQ54EP3.

Family and domain databases

InterProiIPR016819. RNase_P/MRP_POP5.
IPR002759. RNase_P/MRP_subunit.
[Graphical view]
PANTHERiPTHR13004:SF8. PTHR13004:SF8. 1 hit.
PfamiPF01900. RNase_P_Rpp14. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q54EP3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRLKNRYLM TEVIWHDNEK STQLSDSWLF QFISNEVKEK LGELTYEAFK
60 70 80 90 100
KTLKIIYVNP DTNIFIIRVS FEYYKSLWTA LTLITSYYGV PIYFRMVHVG
110 120 130 140 150
GSIRLCQKAA IKIFGKQISV YDKNKILRNE KGETIDNNNN KNEEPSIKMD
160 170
SDDDENGGGD DGEDNDSEMK D
Length:171
Mass (Da):19,916
Last modified:May 24, 2005 - v1
Checksum:i0225413D5ACE16C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000177 Genomic DNA. Translation: EAL61815.1.
RefSeqiXP_635197.1. XM_630105.1.

Genome annotation databases

EnsemblProtistsiDDB0237627; DDB0237627; DDB_G0291662.
GeneIDi8628142.
KEGGiddi:DDB_G0291662.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000177 Genomic DNA. Translation: EAL61815.1.
RefSeqiXP_635197.1. XM_630105.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi44689.DDBDRAFT_0219669.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiDDB0237627; DDB0237627; DDB_G0291662.
GeneIDi8628142.
KEGGiddi:DDB_G0291662.

Organism-specific databases

dictyBaseiDDB_G0291662. pop5.

Phylogenomic databases

eggNOGiCOG1369.
InParanoidiQ54EP3.
KOiK03537.
OMAiFQFISNE.
PhylomeDBiQ54EP3.

Miscellaneous databases

PROiQ54EP3.

Family and domain databases

InterProiIPR016819. RNase_P/MRP_POP5.
IPR002759. RNase_P/MRP_subunit.
[Graphical view]
PANTHERiPTHR13004:SF8. PTHR13004:SF8. 1 hit.
PfamiPF01900. RNase_P_Rpp14. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiPOP5_DICDI
AccessioniPrimary (citable) accession number: Q54EP3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: April 1, 2015
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.