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Protein

Probable serine/threonine-protein kinase DDB_G0291664

Gene

DDB_G0291664

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei509ATPPROSITE-ProRule annotation1
Active sitei610Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi488 – 496ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase DDB_G0291664 (EC:2.7.11.1)
Gene namesi
ORF Names:DDB_G0291664
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 6, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0291664.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003620441 – 959Probable serine/threonine-protein kinase DDB_G0291664Add BLAST959

Proteomic databases

PaxDbiQ54EM1.
PRIDEiQ54EM1.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0229339.

Structurei

3D structure databases

ProteinModelPortaliQ54EM1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati294 – 324ANK 1Add BLAST31
Repeati333 – 362ANK 2Add BLAST30
Domaini482 – 762Protein kinasePROSITE-ProRule annotationAdd BLAST281

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi125 – 160Poly-GlnAdd BLAST36
Compositional biasi163 – 193Pro-richAdd BLAST31
Compositional biasi901 – 918Poly-AsnAdd BLAST18
Compositional biasi937 – 948Poly-SerAdd BLAST12

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

eggNOGiKOG0197. Eukaryota.
COG0515. LUCA.
InParanoidiQ54EM1.
PhylomeDBiQ54EM1.

Family and domain databases

CDDicd00204. ANK. 1 hit.
Gene3Di1.25.40.20. 1 hit.
InterProiView protein in InterPro
IPR020683. Ankyrin_rpt-contain_dom.
IPR036770. Ankyrin_rpt-contain_sf.
IPR011009. Kinase-like_dom_sf.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequencei

Sequence statusi: Complete.

Q54EM1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESKKNSYYK NVMDKIYAKE KDVLSINKDF QENNLTRISL ILNYKDFYLK
60 70 80 90 100
FDESLHGYSF GYVTNLFGLK LYSPFTETVR FDDTEKYMKT ILGVPSNEAL
110 120 130 140 150
PQLCSDQHQN FEEKDPQIEI LPSPQQQQQQ QQQQQQQQQQ QQQQQQQQQQ
160 170 180 190 200
QQQQQQQQQQ LTPPPSPPLL PIPQPPAQNE EQQLTQPPSI PPPQQKQIKI
210 220 230 240 250
QKSDRGTQVK SITNPVNSLS KYINNSSLDY SIKKNYTLEE IYENNKNYMD
260 270 280 290 300
KTNNFLHFLF TFIDKTTIKD LEHFEKEISR VHNIEKLINE QNVKGETPLH
310 320 330 340 350
SLILYNSESC LKKLVIAKIN CMGIFDYSKC DNLNKNLLTH AIEKGDFEII
360 370 380 390 400
KLVLIGGCPL KMSPRSKLFK QNFKLYRQQI YRVFEIKEFL TELGFNQFIP
410 420 430 440 450
MFLEYEFKNI NIYYQIKSFI MVLTLNADEI LRWKSLLEPN KNLDLDSFCI
460 470 480 490 500
EYQIKDQNGS ESQLMADHFK KVCQLNSLFG YIDFHTQIGS AGNASVFEGT
510 520 530 540 550
YKGMPIACKE MPVSGTYEQR VDSIKEIAAV GQIEDLGGCT VVKTVGVLKY
560 570 580 590 600
NEKLFLVMVK EKCNLLSFLS NKSEILKMQR GGIWTSIFKI SKEILKGLIS
610 620 630 640 650
LREVGMYHRD FKTANFLVSN TGKILISDFG TSRDENEKRF NTFAKTIGTL
660 670 680 690 700
WYRCPRLGDC SGDEKTLNHY NEKSEIYSLG IILWELICIA MTGTYVSPKI
710 720 730 740 750
ALFQNEVDFS IWIHKDYRFS FPIGTPQSLV KLITSMCLPC RDRRPTVHQI
760 770 780 790 800
LDEVGIIETE FLSNRGIKGE QTYSGLECWR EFNFSKQNVF GISISNLHDT
810 820 830 840 850
EYKAVNKYNY TSYNNKNSLL MKRYLDNSNF VVELINPNGI FKFKSFFEKE
860 870 880 890 900
KLLYLKLKST YKGEYYFDMG KFLTTIIQIH QITEIYYKML QKYRELGLLR
910 920 930 940 950
NNNNNINNNN NNNNNCNNSK KFKTTSESTS ALGSDASSSS SPSSSSPSPK

YSASIYHHQ
Length:959
Mass (Da):111,306
Last modified:May 24, 2005 - v1
Checksum:i732A025F33F96BA9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000177 Genomic DNA. Translation: EAL61816.1.
RefSeqiXP_635219.1. XM_630127.1.

Genome annotation databases

EnsemblProtistsiEAL61816; EAL61816; DDB_G0291664.
GeneIDi8628166.
KEGGiddi:DDB_G0291664.

Similar proteinsi

Entry informationi

Entry nameiY1664_DICDI
AccessioniPrimary (citable) accession number: Q54EM1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: May 24, 2005
Last modified: November 22, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families