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Protein

Peptidyl-prolyl cis-trans isomerase-like 3

Gene

ppil3

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).By similarity

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase, Rotamase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-prolyl cis-trans isomerase-like 3 (EC:5.2.1.8)
Short name:
PPIase
Alternative name(s):
Rotamase ppil3
Gene namesi
Name:ppil3
ORF Names:DDB_G0291734
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 6, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0291734. ppil3.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 161161Peptidyl-prolyl cis-trans isomerase-like 3PRO_0000328023Add
BLAST

Proteomic databases

PaxDbiQ54E95.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0233550.

Structurei

3D structure databases

ProteinModelPortaliQ54E95.
SMRiQ54E95. Positions 1-159.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 153153PPIase cyclophilin-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 PPIase cyclophilin-type domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0884. Eukaryota.
COG0652. LUCA.
InParanoidiQ54E95.
KOiK12734.
OMAiENPKGGR.
PhylomeDBiQ54E95.

Family and domain databases

Gene3Di2.40.100.10. 1 hit.
InterProiIPR029000. Cyclophilin-like_dom.
IPR024936. Cyclophilin-type_PPIase.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
[Graphical view]
PANTHERiPTHR11071. PTHR11071. 1 hit.
PfamiPF00160. Pro_isomerase. 1 hit.
[Graphical view]
PIRSFiPIRSF001467. Peptidylpro_ismrse. 1 hit.
PRINTSiPR00153. CSAPPISMRASE.
SUPFAMiSSF50891. SSF50891. 1 hit.
PROSITEiPS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q54E95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVTLHTSLG DIKVEIFCDS VPLASENFLA LCASNYYNNT IFHRNIKGFM
60 70 80 90 100
IQGGDPTNTG RGGESIWKKQ FKDEFPSHLK HNTRGILSMA NSGPDTNGSQ
110 120 130 140 150
FFITYGKHRS LNKVYTVFGK IIAGIEVLDL MEKVPVDDKD LPLNEIILKS
160
VTIHANPIAN Q
Length:161
Mass (Da):17,869
Last modified:May 24, 2005 - v1
Checksum:iEE4F6855E9B82136
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000182 Genomic DNA. Translation: EAL61563.1.
RefSeqiXP_629967.1. XM_629965.1.

Genome annotation databases

EnsemblProtistsiDDB0233550; DDB0233550; DDB_G0291734.
GeneIDi8628297.
KEGGiddi:DDB_G0291734.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000182 Genomic DNA. Translation: EAL61563.1.
RefSeqiXP_629967.1. XM_629965.1.

3D structure databases

ProteinModelPortaliQ54E95.
SMRiQ54E95. Positions 1-159.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0233550.

Proteomic databases

PaxDbiQ54E95.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiDDB0233550; DDB0233550; DDB_G0291734.
GeneIDi8628297.
KEGGiddi:DDB_G0291734.

Organism-specific databases

dictyBaseiDDB_G0291734. ppil3.

Phylogenomic databases

eggNOGiKOG0884. Eukaryota.
COG0652. LUCA.
InParanoidiQ54E95.
KOiK12734.
OMAiENPKGGR.
PhylomeDBiQ54E95.

Miscellaneous databases

PROiQ54E95.

Family and domain databases

Gene3Di2.40.100.10. 1 hit.
InterProiIPR029000. Cyclophilin-like_dom.
IPR024936. Cyclophilin-type_PPIase.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
[Graphical view]
PANTHERiPTHR11071. PTHR11071. 1 hit.
PfamiPF00160. Pro_isomerase. 1 hit.
[Graphical view]
PIRSFiPIRSF001467. Peptidylpro_ismrse. 1 hit.
PRINTSiPR00153. CSAPPISMRASE.
SUPFAMiSSF50891. SSF50891. 1 hit.
PROSITEiPS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPPIL3_DICDI
AccessioniPrimary (citable) accession number: Q54E95
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: September 7, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.