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Q54DU9 (TP4AA_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein tyrosine phosphatase type IVA A

EC=3.1.3.48
Gene names
ORF Names:DDB_G0292024
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length166 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Subcellular location

Membrane; Lipid-anchor Potential.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family.

Contains 1 tyrosine-protein phosphatase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 163163Probable protein tyrosine phosphatase type IVA A
PRO_0000329025
Propeptide164 – 1663Removed in mature form By similarity
PRO_0000396656

Regions

Domain85 – 15167Tyrosine-protein phosphatase
Region108 – 1136Phosphate binding By similarity

Sites

Active site751Proton donor By similarity
Active site1071Phosphocysteine intermediate By similarity
Binding site1131Substrate By similarity

Amino acid modifications

Modified residue1631Cysteine methyl ester By similarity
Lipidation1631S-farnesyl cysteine By similarity
Disulfide bond52 ↔ 107 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q54DU9 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: B9A1CE094E6AB73D

FASTA16618,422
        10         20         30         40         50         60 
MTGIRSALPN PASLVESSTH RFLIFDAPND DNLPLYINEL KKYNVSHLVR ACDPTYSTEP 

        70         80         90        100        110        120 
LQAIGIQVHD MPFADGGSPP DAVVNNWIKI LGESYKKDSK ETIGIHCVAG LGRAPVLVAI 

       130        140        150        160 
ALIEGGMNPL QAVEYIRERR RGSINIKQIQ YLKNYKSKKK SSCRIM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000187 Genomic DNA. Translation: EAL61368.1.

3D structure databases

ProteinModelPortalQ54DU9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDBDRAFT_0184168.

Proteomic databases

PRIDEQ54DU9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0238561; DDB0238561; DDB_G0292024.
KEGGddi:DDB_G0292024.

Organism-specific databases

dictyBaseDDB_G0292024.

Phylogenomic databases

eggNOGNOG265664.
KOK18041.
OMAKAKFCDD.
PhylomeDBQ54DU9.
ProtClustDBPTZ00242.

Family and domain databases

InterProIPR000340. Dual-sp_phosphatase_cat-dom.
IPR000387. Tyr/Dual-sp_Pase.
[Graphical view]
PfamPF00782. DSPc. 1 hit.
[Graphical view]
PROSITEPS50056. TYR_PHOSPHATASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTP4AA_DICDI
AccessionPrimary (citable) accession number: Q54DU9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: April 16, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase