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Protein

Mitochondrial substrate carrier family protein P

Gene

mcfP

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Required for the accumulation of coenzyme A in the mitochondrial matrix (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Enzyme and pathway databases

ReactomeiR-DDI-196783. Coenzyme A biosynthesis.

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial substrate carrier family protein P
Alternative name(s):
Solute carrier family 25 member 16 homolog A
Gene namesi
Name:mcfP
Synonyms:slc25a16A
ORF Names:DDB_G0292034
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 6, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0292034. mcfP.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei15 – 35Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei66 – 86Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei107 – 127Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei165 – 185Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei207 – 227Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei262 – 282Helical; Name=6Sequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003294291 – 297Mitochondrial substrate carrier family protein PAdd BLAST297

Proteomic databases

PaxDbiQ54DU1.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0234093.

Structurei

3D structure databases

ProteinModelPortaliQ54DU1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati12 – 98Solcar 1Add BLAST87
Repeati104 – 189Solcar 2Add BLAST86
Repeati201 – 293Solcar 3Add BLAST93

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0752. Eukaryota.
ENOG410ZRF1. LUCA.
InParanoidiQ54DU1.
KOiK15084.
OMAiTHDTVGD.
PhylomeDBiQ54DU1.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR002167. Graves_DC.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
PRINTSiPR00928. GRAVESDC.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

Q54DU1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATTSVSSPK SKPSWVSFLS GGLAGVTAKS AVAPLERVKI LYQIKSELYS
60 70 80 90 100
LNSVYGSMLK IVENEGIKGL WRGNSATILR VFPYAAVQFL SYETIKNHLV
110 120 130 140 150
ADKSSSFQIF LAGSAAGGIA VCATYPLDLL RARLAIEIHK KPTKPHHLLK
160 170 180 190 200
STFTKDGVKG IYRGIQPTLI GILPYGGISF STFEFLKRIA PLNEIDENGQ
210 220 230 240 250
ISGTYKLIAG GIAGGVAQTV AYPFDVVRRR VQTHGFGDAK AVVNLEHGTL
260 270 280 290
RTIAHILKEE GILALYKGLS INYVKVIPTA SIAFYTYEYL SNFFNKL
Length:297
Mass (Da):32,323
Last modified:May 24, 2005 - v1
Checksum:i2ED28CD6A9FCFEF6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000187 Genomic DNA. Translation: EAL61373.1.
RefSeqiXP_629781.1. XM_629779.1.

Genome annotation databases

EnsemblProtistsiEAL61373; EAL61373; DDB_G0292034.
GeneIDi8628458.
KEGGiddi:DDB_G0292034.

Similar proteinsi

Entry informationi

Entry nameiMCFP_DICDI
AccessioniPrimary (citable) accession number: Q54DU1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: September 27, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families