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Q54DM9 (ALG11_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

EC=2.4.1.131
Alternative name(s):
Asparagine-linked glycosylation protein 11 homolog
Glycolipid 2-alpha-mannosyltransferase
Gene names
Name:alg11
ORF Names:DDB_G0292118
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length505 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 GDP-alpha-D-mannose + D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = 2 GDP + D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol.

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the glycosyltransferase group 1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 505505GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
PRO_0000327540

Regions

Transmembrane4 – 2421Helical; Potential
Transmembrane27 – 4721Helical; Potential
Transmembrane146 – 16621Helical; Potential
Transmembrane167 – 18721Helical; Potential

Amino acid modifications

Glycosylation2561N-linked (GlcNAc...) Potential
Glycosylation3621N-linked (GlcNAc...) Potential
Glycosylation4201N-linked (GlcNAc...) Potential
Glycosylation4771N-linked (GlcNAc...) Potential
Glycosylation4911N-linked (GlcNAc...) Potential
Glycosylation4971N-linked (GlcNAc...) Potential
Glycosylation4981N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q54DM9 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 1075BF5D3643A3E9

FASTA50557,519
        10         20         30         40         50         60 
MDELIMMVFV LFTIVLLLTV SMTLAALIST IVVLVVPLII CIIALLIALR IKYGSKKDLS 

        70         80         90        100        110        120 
EVSIGFFHPY CTAGGGGERV LWCAIKSIQE EYPYVRCVVY TGDKESDDEI FNKVKKTFDI 

       130        140        150        160        170        180 
ELGRDNLEFI RLKKRKWVEA STYPRFTLIG QSLGSMILGW EALTKFVPTI FLDSMGYAFT 

       190        200        210        220        230        240 
FPIFSLIGGS TVACYVHYPT ISSDMISSVK SSSYSFNNDV SISSNKFKTI SKLIYYNIFS 

       250        260        270        280        290        300 
KIYQIVGSFS KLVMVNGTWT GNHIRDIWKK QFGYDLFIVY PPVDVKGRKQ LKLGWMDGTR 

       310        320        330        340        350        360 
KNMILSIAQF RPEKNHQLQL RTLAHLLEKY PSHREQPLNT KLVLVGGVRD QADRDRVEQL 

       370        380        390        400        410        420 
RNLSKELNIE DHVEFQIGIS SDQLNQLLSE ASVGIHTMYN EHFGIGVVEL MAAGVIPVAN 

       430        440        450        460        470        480 
NSAGPKEDIV RHEDTGFLAS TIQEYAEYIH EILAYREKYV EMQKKARDST DRFSESNFSN 

       490        500 
QFLKYIKPLI NQSLRNNNSS SKKRN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000187 Genomic DNA. Translation: EAL61415.1.
RefSeqXP_629843.1. XM_629841.1.

3D structure databases

ProteinModelPortalQ54DM9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDB_0231366.

Proteomic databases

PRIDEQ54DM9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0231366; DDB0231366; DDB_G0292118.
GeneID8628523.
KEGGddi:DDB_G0292118.

Organism-specific databases

dictyBaseDDB_G0292118. alg11.

Phylogenomic databases

eggNOGCOG0438.
OMAGTVILAH.
PhylomeDBQ54DM9.

Family and domain databases

InterProIPR001296. Glyco_trans_1.
[Graphical view]
PfamPF00534. Glycos_transf_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROQ54DM9.

Entry information

Entry nameALG11_DICDI
AccessionPrimary (citable) accession number: Q54DM9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: July 9, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase