Reviewed,
UniProtKB/Swiss-Prot Q54DG1 (ALDH3_DICDI)
Last modified
November 3, 2009.
Version 30.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Aldehyde dehydrogenase family 3 comG EC=1.2.1.5 Alternative name(s): Communication mutant protein G | ||||
| Gene names |
| ||||
| Organism | Dictyostelium discoideum (Slime mold) [Complete proteome] | ||||
| Taxonomic identifier | 44689 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium |
Protein attributes
| Sequence length | 470 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | An aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H. |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the aldehyde dehydrogenase family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | cellular aldehyde metabolic process Inferred from electronic annotation. Source: InterPro oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | aldehyde dehydrogenase [NAD(P)+] activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. Kuspa A.Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4. |
| [2] | "A novel developmental mechanism in Dictyostelium revealed in a screen for communication mutants." Kibler K., Nguyen T.-L., Svetz J., Van Driessche N., Ibarra M., Thompson C., Shaw C., Shaulsky G. Dev. Biol. 259:193-208(2003) [PubMed: 12871696] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 269-347. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| AAFI02000189 Genomic DNA. Translation: EAL61259.1. AY221644 Genomic DNA. Translation: AAO34400.1. | |
| RefSeq | XP_629680.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q54DG1. |
Genome annotation databases | |
| GeneID | 3386347. |
| GenomeReviews | Gene locus comG in contig CM000155_GR. |
| KEGG | ddi:DDB_0185188. |
Organism-specific databases | |
| dictyBase | DDB_G0292270. comG. |
Phylogenomic databases | |
| OMA | ITELLEY. |
Family and domain databases | |
| InterPro | IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH. IPR012394. Aldehyde_DH_NAD(P). [Graphical view] |
| Gene3D | G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit. |
| PANTHER | PTHR11699. Aldehyde_dehyd. 1 hit. PTHR11699:SF15. ALDH. 1 hit. |
| Pfam | PF00171. Aldedh. 3 hits. [Graphical view] |
| PIRSF | PIRSF036492. ALDH. 1 hit. |
| PROSITE | PS00070. ALDEHYDE_DEHYDR_CYS. False negative. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ALDH3_DICDI | ||||||||
| Accession | Primary (citable) accession number: Q54DG1 Secondary accession number(s): Q86MX3 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
Relevant documents
| Dictyostelium discoideum Dictyostelium discoideum: entries, gene names and cross-references to dictyBase |
| SIMILARITY comments Index of protein domains and families |

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