Q54DD3 (GCST_DICDI) Reviewed, UniProtKB/Swiss-Prot
Last modified
November 16, 2011.
Version 50.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Aminomethyltransferase, mitochondrial EC=2.1.2.10 Alternative name(s): Glycine cleavage system T protein Short name=GCVT | ||||
| Gene names |
| ||||
| Organism | Dictyostelium discoideum (Slime mold) | ||||
| Taxonomic identifier | 44689 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium |
Protein attributes
| Sequence length | 403 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | The glycine cleavage system catalyzes the degradation of glycine By similarity. |
| Catalytic activity | [Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. |
| Subunit structure | The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. |
| Subcellular location | Mitochondrion By similarity. |
| Sequence similarities | Belongs to the GcvT family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Mitochondrion |
| Domain | Transit peptide |
| Molecular function | Aminotransferase Transferase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | glycine catabolic process Inferred from electronic annotation. Source: InterPro |
| Cellular component | glycine cleavage complex Inferred from sequence or structural similarity. Source: dictyBase mitochondrionInferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | aminomethyltransferase activity Inferred from electronic annotation. Source: EC transaminase activityInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
| ||||||||||||||||||
References
| [1] | "The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. Kuspa A.Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AAFI02000189 Genomic DNA. Translation: EAL61287.1. |
| RefSeq | XP_629708.1. XM_629706.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1WSR based on UniProtKB P48728. |
| ProteinModelPortal | Q54DD3. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q54DD3. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblProtists | DDB0231218; DDB0231218; DDB_G0292326. |
| GeneID | 8628622. |
| GenomeReviews | Gene locus gcvT in contig CM000155_GR. |
| KEGG | ddi:DDB_G0292326. |
Organism-specific databases | |
| dictyBase | DDB_G0292326. gcvT. |
Phylogenomic databases | |
| eggNOG | KOG2770. |
| GeneTree | EPrGT00050000002466. |
| HOGENOM | HBG299834. |
| OMA | RITRCGY. |
| PhylomeDB | Q54DD3. |
| ProtClustDB | CLSZ2429438. |
Family and domain databases | |
| InterPro | IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. [Graphical view] |
| KO | K00605. |
| PANTHER | PTHR13847:SF5. PTHR13847:SF5. 1 hit. |
| Pfam | PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view] |
| PIRSF | PIRSF006487. GcvT. 1 hit. |
| TIGRFAMs | TIGR00528. GcvT. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | GCST_DICDI | ||||||||
| Accession | Primary (citable) accession number: Q54DD3 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
Relevant documents
| Dictyostelium discoideum Dictyostelium discoideum: entries, gene names and cross-references to dictyBase |
| SIMILARITY comments Index of protein domains and families |

Clusters with