Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable cyclin-dependent serine/threonine-protein kinase DDB_G0292550

Gene

DDB_G0292550

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei33ATPPROSITE-ProRule annotation1
Active sitei124Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 18ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cyclin-dependent serine/threonine-protein kinase DDB_G0292550 (EC:2.7.11.22)
Gene namesi
ORF Names:DDB_G0292550
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 6, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0292550.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003620471 – 1397Probable cyclin-dependent serine/threonine-protein kinase DDB_G0292550Add BLAST1397

Proteomic databases

PaxDbiQ54D75.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0229424.

Structurei

3D structure databases

ProteinModelPortaliQ54D75.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 287Protein kinasePROSITE-ProRule annotationAdd BLAST284

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi319 – 325Poly-Asn7
Compositional biasi410 – 422Poly-AsnAdd BLAST13
Compositional biasi426 – 460Poly-AsnAdd BLAST35
Compositional biasi463 – 473Poly-AsnAdd BLAST11
Compositional biasi476 – 483Poly-Asn8
Compositional biasi487 – 526Poly-AsnAdd BLAST40
Compositional biasi546 – 550Poly-Asn5
Compositional biasi553 – 568Poly-AsnAdd BLAST16
Compositional biasi649 – 655Poly-Gln7
Compositional biasi688 – 710Poly-AsnAdd BLAST23
Compositional biasi730 – 735Poly-Asn6
Compositional biasi739 – 751Poly-AsnAdd BLAST13
Compositional biasi767 – 799Poly-AsnAdd BLAST33
Compositional biasi830 – 833Poly-Asn4
Compositional biasi844 – 855Poly-AsnAdd BLAST12
Compositional biasi863 – 869Poly-Thr7
Compositional biasi872 – 921Poly-AsnAdd BLAST50
Compositional biasi924 – 940Poly-AsnAdd BLAST17
Compositional biasi1012 – 1017Poly-Asn6
Compositional biasi1031 – 1091Poly-AsnAdd BLAST61
Compositional biasi1123 – 1133Poly-AsnAdd BLAST11
Compositional biasi1136 – 1149Poly-AsnAdd BLAST14
Compositional biasi1180 – 1187Poly-Ser8
Compositional biasi1193 – 1198Poly-Ser6
Compositional biasi1201 – 1206Poly-Ser6
Compositional biasi1253 – 1320Poly-AsnAdd BLAST68
Compositional biasi1340 – 1343Poly-Lys4
Compositional biasi1357 – 1380Gln-richAdd BLAST24

Sequence similaritiesi

Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0594. Eukaryota.
ENOG410XPP3. LUCA.
InParanoidiQ54D75.
OMAiSEDERIC.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q54D75-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSFQIIELI GSGSYGKVYK AIHNLSKCTV ALKIISVMNI ENGLPVEVKY
60 70 80 90 100
LMKLRDCKNI VHLIEYFYSN DDKLVMVFEY LEYDLWKFIS PKNKYMTLSC
110 120 130 140 150
TKFFIHQLLE GLDELHSQKI MHLDIKPSNL LINPRFDLKI ADFGFTTYIG
160 170 180 190 200
NPHLAHQVIS LFYRPPELLM GSRNYGPEVD IWSVGCIIVE MLTGFYMFAG
210 220 230 240 250
SNDSLQLELI FKTFGTPTEK NWPGISKLSG YSPYLGSKSK KYPSKSLKDI
260 270 280 290 300
SKFKSFSNST LDIILRMLTL CPKNRISTKE ALNHPWFFED PIASPPLDDI
310 320 330 340 350
INCLVSRPVK ISKQHQKTNN CNNNNGSYDI IPPNSILVPK RSSSQQAALQ
360 370 380 390 400
TQQVVDVDLQ YLILKAEQQQ IQYQKLVLQT SVPNHIYKEV YEVNQLLKQY
410 420 430 440 450
ILRLKQQKVN LNNNNLNNNN NNLYGNNNHN NNNNNNNNNN NNNNNNNYNN
460 470 480 490 500
NNNNHNNNYN HDNNNNNNYN NNNYKNNNNS NNNFSFNNSN NNNNNNNNNN
510 520 530 540 550
RNNRNNNNNN NNNNNNNNYN NNSNNNSYNN NFNNGFNNND NINDDNNNNN
560 570 580 590 600
SYNNVNNNNI NNNNNNNNGF NGFNNYGNNF NNSNNNGNQF GANNNSFNNT
610 620 630 640 650
DFSNDSNYGS YCNGLMDLIN NNSMYNGGNY YMNNASFHQR IQEHIQKIQQ
660 670 680 690 700
QQLQQMEDQQ QEKLNFRDYH PLSIPSQHHN TSSSDTHNNN NNNYNNNNNN
710 720 730 740 750
NNNINNNNIN SIHNQSSDHN HFIPNNGFTN ENNNNHCINN MNNSNNNNNN
760 770 780 790 800
NIGNIGSNGG SINEMGNNNN NNNNNNNNNN NNNNNNNNIN ANHNRNNNNG
810 820 830 840 850
SNDFSDFNGN QMVINSYNNN SNNNGNINGN NNNGNGNING IIGNNNNNNS
860 870 880 890 900
NNNNNTSFNG NRTTTTTTTS SNFNNINNNN NNSNNNNKNN NNKNNNNNNN
910 920 930 940 950
NNNNNNNNNN NNNNNNNSNN NSINNNTNNN NNNNNNNNGN GLTSSYANHF
960 970 980 990 1000
QYNHPPFNIS NAPHPIPFLN NQSIPNSNYQ FLNRFSFSNY SNNNSNGLAN
1010 1020 1030 1040 1050
NYQNPFGHGA TNSNNNNSGN NDHVFGHNTF NFNQNNNNNN NNNNNNNNNN
1060 1070 1080 1090 1100
NNNNNNNSNN NSNNNNYNSN NNDNSNSNSN NNNNNNNNNN NSLFNNFNTH
1110 1120 1130 1140 1150
NNSINRGNNS FDSFNNGFNH LKNNNNNINN NNNDINNNNN NNNNNNNNNG
1160 1170 1180 1190 1200
ITKNNTQFGP NILSSTQTSH NSPVSLTPIS VSSSSFSNYS PTSFSSSSME
1210 1220 1230 1240 1250
SLSSSSEFLS SESLSFTNSN QFSPLLNSAS QDINNNSRSS RHRSKLNIDT
1260 1270 1280 1290 1300
KGNNNNNNNN KNNNNNNNNN NNNNNNNNNN NNNSNNINND NNNNSNNNSN
1310 1320 1330 1340 1350
SNNNNSNSNN NNNSNNNNNN SFGLKRYVDD NEEQLLANQK KKKNIKSSPL
1360 1370 1380 1390
PSASSSQQSQ TQQQHQIQQQ SQTQQQSQTQ KIENNDGLSV ENPIVLD
Length:1,397
Mass (Da):158,111
Last modified:May 24, 2005 - v1
Checksum:i2604DAB60C955BCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000190 Genomic DNA. Translation: EAL61254.1.
RefSeqiXP_629621.1. XM_629619.1.

Genome annotation databases

EnsemblProtistsiEAL61254; EAL61254; DDB_G0292550.
GeneIDi8628684.
KEGGiddi:DDB_G0292550.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000190 Genomic DNA. Translation: EAL61254.1.
RefSeqiXP_629621.1. XM_629619.1.

3D structure databases

ProteinModelPortaliQ54D75.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0229424.

Proteomic databases

PaxDbiQ54D75.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAL61254; EAL61254; DDB_G0292550.
GeneIDi8628684.
KEGGiddi:DDB_G0292550.

Organism-specific databases

dictyBaseiDDB_G0292550.

Phylogenomic databases

eggNOGiKOG0594. Eukaryota.
ENOG410XPP3. LUCA.
InParanoidiQ54D75.
OMAiSEDERIC.

Miscellaneous databases

PROiQ54D75.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY2550_DICDI
AccessioniPrimary (citable) accession number: Q54D75
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: May 24, 2005
Last modified: November 2, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.