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Q54D75 (Y2550_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cyclin-dependent serine/threonine-protein kinase DDB_G0292550

EC=2.7.11.22
Gene names
ORF Names:DDB_G0292550
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length1397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 13971397Probable cyclin-dependent serine/threonine-protein kinase DDB_G0292550
PRO_0000362047

Regions

Domain4 – 287284Protein kinase
Nucleotide binding10 – 189ATP By similarity
Compositional bias319 – 3257Poly-Asn
Compositional bias410 – 42213Poly-Asn
Compositional bias426 – 46035Poly-Asn
Compositional bias463 – 47311Poly-Asn
Compositional bias476 – 4838Poly-Asn
Compositional bias487 – 52640Poly-Asn
Compositional bias546 – 5505Poly-Asn
Compositional bias553 – 56816Poly-Asn
Compositional bias649 – 6557Poly-Gln
Compositional bias688 – 71023Poly-Asn
Compositional bias730 – 7356Poly-Asn
Compositional bias739 – 75113Poly-Asn
Compositional bias767 – 79933Poly-Asn
Compositional bias830 – 8334Poly-Asn
Compositional bias844 – 85512Poly-Asn
Compositional bias863 – 8697Poly-Thr
Compositional bias872 – 92150Poly-Asn
Compositional bias924 – 94017Poly-Asn
Compositional bias1012 – 10176Poly-Asn
Compositional bias1031 – 109161Poly-Asn
Compositional bias1123 – 113311Poly-Asn
Compositional bias1136 – 114914Poly-Asn
Compositional bias1180 – 11878Poly-Ser
Compositional bias1193 – 11986Poly-Ser
Compositional bias1201 – 12066Poly-Ser
Compositional bias1253 – 132068Poly-Asn
Compositional bias1340 – 13434Poly-Lys
Compositional bias1357 – 138024Gln-rich

Sites

Active site1241Proton acceptor By similarity
Binding site331ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q54D75 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 2604DAB60C955BCE

FASTA1,397158,111
        10         20         30         40         50         60 
MNSFQIIELI GSGSYGKVYK AIHNLSKCTV ALKIISVMNI ENGLPVEVKY LMKLRDCKNI 

        70         80         90        100        110        120 
VHLIEYFYSN DDKLVMVFEY LEYDLWKFIS PKNKYMTLSC TKFFIHQLLE GLDELHSQKI 

       130        140        150        160        170        180 
MHLDIKPSNL LINPRFDLKI ADFGFTTYIG NPHLAHQVIS LFYRPPELLM GSRNYGPEVD 

       190        200        210        220        230        240 
IWSVGCIIVE MLTGFYMFAG SNDSLQLELI FKTFGTPTEK NWPGISKLSG YSPYLGSKSK 

       250        260        270        280        290        300 
KYPSKSLKDI SKFKSFSNST LDIILRMLTL CPKNRISTKE ALNHPWFFED PIASPPLDDI 

       310        320        330        340        350        360 
INCLVSRPVK ISKQHQKTNN CNNNNGSYDI IPPNSILVPK RSSSQQAALQ TQQVVDVDLQ 

       370        380        390        400        410        420 
YLILKAEQQQ IQYQKLVLQT SVPNHIYKEV YEVNQLLKQY ILRLKQQKVN LNNNNLNNNN 

       430        440        450        460        470        480 
NNLYGNNNHN NNNNNNNNNN NNNNNNNYNN NNNNHNNNYN HDNNNNNNYN NNNYKNNNNS 

       490        500        510        520        530        540 
NNNFSFNNSN NNNNNNNNNN RNNRNNNNNN NNNNNNNNYN NNSNNNSYNN NFNNGFNNND 

       550        560        570        580        590        600 
NINDDNNNNN SYNNVNNNNI NNNNNNNNGF NGFNNYGNNF NNSNNNGNQF GANNNSFNNT 

       610        620        630        640        650        660 
DFSNDSNYGS YCNGLMDLIN NNSMYNGGNY YMNNASFHQR IQEHIQKIQQ QQLQQMEDQQ 

       670        680        690        700        710        720 
QEKLNFRDYH PLSIPSQHHN TSSSDTHNNN NNNYNNNNNN NNNINNNNIN SIHNQSSDHN 

       730        740        750        760        770        780 
HFIPNNGFTN ENNNNHCINN MNNSNNNNNN NIGNIGSNGG SINEMGNNNN NNNNNNNNNN 

       790        800        810        820        830        840 
NNNNNNNNIN ANHNRNNNNG SNDFSDFNGN QMVINSYNNN SNNNGNINGN NNNGNGNING 

       850        860        870        880        890        900 
IIGNNNNNNS NNNNNTSFNG NRTTTTTTTS SNFNNINNNN NNSNNNNKNN NNKNNNNNNN 

       910        920        930        940        950        960 
NNNNNNNNNN NNNNNNNSNN NSINNNTNNN NNNNNNNNGN GLTSSYANHF QYNHPPFNIS 

       970        980        990       1000       1010       1020 
NAPHPIPFLN NQSIPNSNYQ FLNRFSFSNY SNNNSNGLAN NYQNPFGHGA TNSNNNNSGN 

      1030       1040       1050       1060       1070       1080 
NDHVFGHNTF NFNQNNNNNN NNNNNNNNNN NNNNNNNSNN NSNNNNYNSN NNDNSNSNSN 

      1090       1100       1110       1120       1130       1140 
NNNNNNNNNN NSLFNNFNTH NNSINRGNNS FDSFNNGFNH LKNNNNNINN NNNDINNNNN 

      1150       1160       1170       1180       1190       1200 
NNNNNNNNNG ITKNNTQFGP NILSSTQTSH NSPVSLTPIS VSSSSFSNYS PTSFSSSSME 

      1210       1220       1230       1240       1250       1260 
SLSSSSEFLS SESLSFTNSN QFSPLLNSAS QDINNNSRSS RHRSKLNIDT KGNNNNNNNN 

      1270       1280       1290       1300       1310       1320 
KNNNNNNNNN NNNNNNNNNN NNNSNNINND NNNNSNNNSN SNNNNSNSNN NNNSNNNNNN 

      1330       1340       1350       1360       1370       1380 
SFGLKRYVDD NEEQLLANQK KKKNIKSSPL PSASSSQQSQ TQQQHQIQQQ SQTQQQSQTQ 

      1390 
KIENNDGLSV ENPIVLD 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000190 Genomic DNA. Translation: EAL61254.1.

3D structure databases

ProteinModelPortalQ54D75.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDB_0229424.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0229424; DDB0229424; DDB_G0292550.
KEGGddi:DDB_G0292550.

Organism-specific databases

dictyBaseDDB_G0292550.

Phylogenomic databases

eggNOGCOG0515.
InParanoidQ54D75.
OMANNINANH.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY2550_DICDI
AccessionPrimary (citable) accession number: Q54D75
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: May 24, 2005
Last modified: April 16, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase