Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q54D75

- Y2550_DICDI

UniProt

Q54D75 - Y2550_DICDI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable cyclin-dependent serine/threonine-protein kinase DDB_G0292550

Gene

DDB_G0292550

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei33 – 331ATPPROSITE-ProRule annotation
Active sitei124 – 1241Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 189ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. cyclin-dependent protein serine/threonine kinase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cyclin-dependent serine/threonine-protein kinase DDB_G0292550 (EC:2.7.11.22)
Gene namesi
ORF Names:DDB_G0292550
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 6, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0292550.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13971397Probable cyclin-dependent serine/threonine-protein kinase DDB_G0292550PRO_0000362047Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB_0229424.

Structurei

3D structure databases

ProteinModelPortaliQ54D75.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 287284Protein kinasePROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi319 – 3257Poly-Asn
Compositional biasi410 – 42213Poly-AsnAdd
BLAST
Compositional biasi426 – 46035Poly-AsnAdd
BLAST
Compositional biasi463 – 47311Poly-AsnAdd
BLAST
Compositional biasi476 – 4838Poly-Asn
Compositional biasi487 – 52640Poly-AsnAdd
BLAST
Compositional biasi546 – 5505Poly-Asn
Compositional biasi553 – 56816Poly-AsnAdd
BLAST
Compositional biasi649 – 6557Poly-Gln
Compositional biasi688 – 71023Poly-AsnAdd
BLAST
Compositional biasi730 – 7356Poly-Asn
Compositional biasi739 – 75113Poly-AsnAdd
BLAST
Compositional biasi767 – 79933Poly-AsnAdd
BLAST
Compositional biasi830 – 8334Poly-Asn
Compositional biasi844 – 85512Poly-AsnAdd
BLAST
Compositional biasi863 – 8697Poly-Thr
Compositional biasi872 – 92150Poly-AsnAdd
BLAST
Compositional biasi924 – 94017Poly-AsnAdd
BLAST
Compositional biasi1012 – 10176Poly-Asn
Compositional biasi1031 – 109161Poly-AsnAdd
BLAST
Compositional biasi1123 – 113311Poly-AsnAdd
BLAST
Compositional biasi1136 – 114914Poly-AsnAdd
BLAST
Compositional biasi1180 – 11878Poly-Ser
Compositional biasi1193 – 11986Poly-Ser
Compositional biasi1201 – 12066Poly-Ser
Compositional biasi1253 – 132068Poly-AsnAdd
BLAST
Compositional biasi1340 – 13434Poly-Lys
Compositional biasi1357 – 138024Gln-richAdd
BLAST

Sequence similaritiesi

Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0515.
InParanoidiQ54D75.
OMAiNNINANH.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q54D75-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNSFQIIELI GSGSYGKVYK AIHNLSKCTV ALKIISVMNI ENGLPVEVKY
60 70 80 90 100
LMKLRDCKNI VHLIEYFYSN DDKLVMVFEY LEYDLWKFIS PKNKYMTLSC
110 120 130 140 150
TKFFIHQLLE GLDELHSQKI MHLDIKPSNL LINPRFDLKI ADFGFTTYIG
160 170 180 190 200
NPHLAHQVIS LFYRPPELLM GSRNYGPEVD IWSVGCIIVE MLTGFYMFAG
210 220 230 240 250
SNDSLQLELI FKTFGTPTEK NWPGISKLSG YSPYLGSKSK KYPSKSLKDI
260 270 280 290 300
SKFKSFSNST LDIILRMLTL CPKNRISTKE ALNHPWFFED PIASPPLDDI
310 320 330 340 350
INCLVSRPVK ISKQHQKTNN CNNNNGSYDI IPPNSILVPK RSSSQQAALQ
360 370 380 390 400
TQQVVDVDLQ YLILKAEQQQ IQYQKLVLQT SVPNHIYKEV YEVNQLLKQY
410 420 430 440 450
ILRLKQQKVN LNNNNLNNNN NNLYGNNNHN NNNNNNNNNN NNNNNNNYNN
460 470 480 490 500
NNNNHNNNYN HDNNNNNNYN NNNYKNNNNS NNNFSFNNSN NNNNNNNNNN
510 520 530 540 550
RNNRNNNNNN NNNNNNNNYN NNSNNNSYNN NFNNGFNNND NINDDNNNNN
560 570 580 590 600
SYNNVNNNNI NNNNNNNNGF NGFNNYGNNF NNSNNNGNQF GANNNSFNNT
610 620 630 640 650
DFSNDSNYGS YCNGLMDLIN NNSMYNGGNY YMNNASFHQR IQEHIQKIQQ
660 670 680 690 700
QQLQQMEDQQ QEKLNFRDYH PLSIPSQHHN TSSSDTHNNN NNNYNNNNNN
710 720 730 740 750
NNNINNNNIN SIHNQSSDHN HFIPNNGFTN ENNNNHCINN MNNSNNNNNN
760 770 780 790 800
NIGNIGSNGG SINEMGNNNN NNNNNNNNNN NNNNNNNNIN ANHNRNNNNG
810 820 830 840 850
SNDFSDFNGN QMVINSYNNN SNNNGNINGN NNNGNGNING IIGNNNNNNS
860 870 880 890 900
NNNNNTSFNG NRTTTTTTTS SNFNNINNNN NNSNNNNKNN NNKNNNNNNN
910 920 930 940 950
NNNNNNNNNN NNNNNNNSNN NSINNNTNNN NNNNNNNNGN GLTSSYANHF
960 970 980 990 1000
QYNHPPFNIS NAPHPIPFLN NQSIPNSNYQ FLNRFSFSNY SNNNSNGLAN
1010 1020 1030 1040 1050
NYQNPFGHGA TNSNNNNSGN NDHVFGHNTF NFNQNNNNNN NNNNNNNNNN
1060 1070 1080 1090 1100
NNNNNNNSNN NSNNNNYNSN NNDNSNSNSN NNNNNNNNNN NSLFNNFNTH
1110 1120 1130 1140 1150
NNSINRGNNS FDSFNNGFNH LKNNNNNINN NNNDINNNNN NNNNNNNNNG
1160 1170 1180 1190 1200
ITKNNTQFGP NILSSTQTSH NSPVSLTPIS VSSSSFSNYS PTSFSSSSME
1210 1220 1230 1240 1250
SLSSSSEFLS SESLSFTNSN QFSPLLNSAS QDINNNSRSS RHRSKLNIDT
1260 1270 1280 1290 1300
KGNNNNNNNN KNNNNNNNNN NNNNNNNNNN NNNSNNINND NNNNSNNNSN
1310 1320 1330 1340 1350
SNNNNSNSNN NNNSNNNNNN SFGLKRYVDD NEEQLLANQK KKKNIKSSPL
1360 1370 1380 1390
PSASSSQQSQ TQQQHQIQQQ SQTQQQSQTQ KIENNDGLSV ENPIVLD
Length:1,397
Mass (Da):158,111
Last modified:May 24, 2005 - v1
Checksum:i2604DAB60C955BCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000190 Genomic DNA. Translation: EAL61254.1.
RefSeqiXP_629621.1. XM_629619.1.

Genome annotation databases

EnsemblProtistsiDDB0229424; DDB0229424; DDB_G0292550.
GeneIDi8628684.
KEGGiddi:DDB_G0292550.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000190 Genomic DNA. Translation: EAL61254.1 .
RefSeqi XP_629621.1. XM_629619.1.

3D structure databases

ProteinModelPortali Q54D75.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 44689.DDB_0229424.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0229424 ; DDB0229424 ; DDB_G0292550 .
GeneIDi 8628684.
KEGGi ddi:DDB_G0292550.

Organism-specific databases

dictyBasei DDB_G0292550.

Phylogenomic databases

eggNOGi COG0515.
InParanoidi Q54D75.
OMAi NNINANH.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiY2550_DICDI
AccessioniPrimary (citable) accession number: Q54D75
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: May 24, 2005
Last modified: November 26, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3