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Protein

ABC transporter G family member 10

Gene

abcG10

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi874 – 881ATPPROSITE-ProRule annotation8

GO - Molecular functioni

  • ATPase activity, coupled to transmembrane movement of substances Source: dictyBase
  • ATP binding Source: UniProtKB-KW

GO - Biological processi

  • aggregation involved in sorocarp development Source: dictyBase
  • culmination involved in sorocarp development Source: GO_Central
  • sorocarp morphogenesis Source: dictyBase
  • transport Source: dictyBase
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DDI-1369062. ABC transporters in lipid homeostasis.
R-DDI-265473. Trafficking of dietary sterols.

Protein family/group databases

TCDBi3.A.1.205.19. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter G family member 10
Alternative name(s):
ABC transporter ABCG.10
Gene namesi
Name:abcG10
ORF Names:DDB_G0292986
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 6, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0292986. abcG10.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei501 – 521HelicalSequence analysisAdd BLAST21
Transmembranei537 – 557HelicalSequence analysisAdd BLAST21
Transmembranei586 – 606HelicalSequence analysisAdd BLAST21
Transmembranei611 – 631HelicalSequence analysisAdd BLAST21
Transmembranei641 – 661HelicalSequence analysisAdd BLAST21
Transmembranei767 – 787HelicalSequence analysisAdd BLAST21
Transmembranei1178 – 1198HelicalSequence analysisAdd BLAST21
Transmembranei1214 – 1234HelicalSequence analysisAdd BLAST21
Transmembranei1253 – 1273HelicalSequence analysisAdd BLAST21
Transmembranei1290 – 1310HelicalSequence analysisAdd BLAST21
Transmembranei1319 – 1339HelicalSequence analysisAdd BLAST21
Transmembranei1440 – 1460HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003913971 – 1466ABC transporter G family member 10Add BLAST1466

Proteomic databases

PaxDbiQ54CG0.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0214895.

Structurei

3D structure databases

ProteinModelPortaliQ54CG0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini138 – 392ABC transporter 1PROSITE-ProRule annotationAdd BLAST255
Domaini497 – 724ABC transmembrane type-2 1Add BLAST228
Domaini838 – 1082ABC transporter 2PROSITE-ProRule annotationAdd BLAST245
Domaini1177 – 1399ABC transmembrane type-2 2Add BLAST223

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi29 – 36Poly-Asn8

Sequence similaritiesi

Contains 2 ABC transporter domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0065. Eukaryota.
COG0842. LUCA.
COG1131. LUCA.
InParanoidiQ54CG0.
OMAiISIVIVE.
PhylomeDBiQ54CG0.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR013525. ABC_2_trans.
IPR029481. ABC_trans_N.
IPR003439. ABC_transporter-like.
IPR027417. P-loop_NTPase.
IPR010929. PDR_CDR_ABC.
[Graphical view]
PfamiPF01061. ABC2_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
PF14510. ABC_trans_N. 1 hit.
PF06422. PDR_CDR. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q54CG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDDYELKEL QPPEGANCNY NINTPQYENN NNNNNNTSGN ESPNILNSEN
60 70 80 90 100
QFNQVANELE NDSKQFFSNQ DPEMNVEHSN VAQNEQDFKL RSYFENSQRI
110 120 130 140 150
ALGNGQKPKK MGISIRNLTV VGKGADISVI SDLSTPFVTI FNLFRPSTWR
160 170 180 190 200
KSSGSTFDIL HDVTLFNRDA EMLLVLGRPG AGCSTLLRVI SNQRSSYVSV
210 220 230 240 250
SGDVTYGGIN SDEWKNFKGE SIYTPEEDTH HPTLTVRETL NFALKCKTIH
260 270 280 290 300
NRLPDEKKKT FRKKIYDLLV GMFGISKQSD TLVGNEFIRG LSGGERKRLT
310 320 330 340 350
ITEAMVSSAS ITCYDCSTRG LDAASALDYA KSIRIMSDTL HKTTIASFYQ
360 370 380 390 400
ASDSIFNLFN NVAILEKGRL IYFGPVGLAK QYFLDLGFDC EPRKSTPDFL
410 420 430 440 450
TGVTNPQERK VRPGFEGRAP ETSSDFEKAW KSSDLYQVML QQQLEYEKKI
460 470 480 490 500
ELEQPSTNFI EQIRNENSKT NPTKSIYTTS YFTQVRALIA RNSQIIWGDR
510 520 530 540 550
FALISKYISI IVQTFVYASL FYNMKSDVTG LFNRGGAIYA AILFNAFVSA
560 570 580 590 600
GELGLTFYGR RILQKQHSYA MYRPSALHIA MVITDIPLTA IQVTIFSVIV
610 620 630 640 650
YFMYGLQVDA GKFFIFLFTI FGSTLSMVAF FRALGNLSPS LYVSQNILNV
660 670 680 690 700
FILFMFTYGG YSIPKNKMHP WFSWYFWINP FSFPYKALMA NEFGDMNFTC
710 720 730 740 750
NDQTAIPNGN YIASNGSTMS YQDQYRACPS AGAIEGQMVN GEFYVAGSNY
760 770 780 790 800
IDAALDFKSD DRTLNVIITF LWWIFFVIIN MIALELFDWT SGGMPHKVYK
810 820 830 840 850
RGKAPKINDD EEERQQNAMV ENATSKMKDT LKMRESCFTW NHIHYTVQLN
860 870 880 890 900
GKDLLLLNDV EGWIKPGQMT ALMGSSGAGK TTLLDVLAKR KTMGTVTGKC
910 920 930 940 950
LLNGKELNID FERITGYVEQ MDVHNPGLTV REALRFSAKL RQEPTVSLQD
960 970 980 990 1000
KYEYVEQVLE MMEMKHLGDA LIGSLETGIG ISVEERKRLT IGIELVAKPH
1010 1020 1030 1040 1050
ILFLDEPTSG LDSQSSYNIV KFIRKLADAG MPLVCTIHQP SSVLFEYFDR
1060 1070 1080 1090 1100
ILLLAKGGKT VYYGDIGEKS KTLTSYFERN GVRSCTESEN PAEYILEAIG
1110 1120 1130 1140 1150
AGTNPGVSTI DWPEVWKQSP ELQDVQAELA SLETAATVQI SSDDQDHGPP
1160 1170 1180 1190 1200
REFATSIWYQ TWEVYKRLNL IWWRDMSYVY GIFTQAAASG LIIGFTFWNL
1210 1220 1230 1240 1250
DLSSSDMNQR VFFIFEILFL GILYIFIAIP QFLIQKAYFK KDYASKFYSW
1260 1270 1280 1290 1300
CPFAISIVIV ELPFVAVAGT ICFFCSFWTA GIYYNGEYDF YFYITFILFL
1310 1320 1330 1340 1350
FICVSLGQVV SAFCFNVMLA QTILPLLLVM LFLFCGVLVP YEQIPNFWKF
1360 1370 1380 1390 1400
VYHSNPCRYF LEGVVTSVLK NVFVDCSNED LTKFSNPTNL TCKEYFKPTY
1410 1420 1430 1440 1450
GNVRAVTKGD ESECGYCVFK SGEEYYKTLG WSYENRLRNY GILWAFFIFN
1460
IIMVVSFVYL TKKPNR
Length:1,466
Mass (Da):166,602
Last modified:May 24, 2005 - v1
Checksum:iB494D9725C437B63
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti211S → F in AAL91496 (PubMed:12456012).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF482389 Genomic DNA. Translation: AAL91496.1.
AAFI02000198 Genomic DNA. Translation: EAL60948.1.
RefSeqiXP_629362.1. XM_629360.1.

Genome annotation databases

EnsemblProtistsiEAL60948; EAL60948; DDB_G0292986.
GeneIDi8628979.
KEGGiddi:DDB_G0292986.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF482389 Genomic DNA. Translation: AAL91496.1.
AAFI02000198 Genomic DNA. Translation: EAL60948.1.
RefSeqiXP_629362.1. XM_629360.1.

3D structure databases

ProteinModelPortaliQ54CG0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0214895.

Protein family/group databases

TCDBi3.A.1.205.19. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiQ54CG0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAL60948; EAL60948; DDB_G0292986.
GeneIDi8628979.
KEGGiddi:DDB_G0292986.

Organism-specific databases

dictyBaseiDDB_G0292986. abcG10.

Phylogenomic databases

eggNOGiKOG0065. Eukaryota.
COG0842. LUCA.
COG1131. LUCA.
InParanoidiQ54CG0.
OMAiISIVIVE.
PhylomeDBiQ54CG0.

Enzyme and pathway databases

ReactomeiR-DDI-1369062. ABC transporters in lipid homeostasis.
R-DDI-265473. Trafficking of dietary sterols.

Miscellaneous databases

PROiQ54CG0.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR013525. ABC_2_trans.
IPR029481. ABC_trans_N.
IPR003439. ABC_transporter-like.
IPR027417. P-loop_NTPase.
IPR010929. PDR_CDR_ABC.
[Graphical view]
PfamiPF01061. ABC2_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
PF14510. ABC_trans_N. 1 hit.
PF06422. PDR_CDR. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiABCGA_DICDI
AccessioniPrimary (citable) accession number: Q54CG0
Secondary accession number(s): Q8T682
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 9, 2010
Last sequence update: May 24, 2005
Last modified: November 2, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.