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Q54C64 (PIGL_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase

EC=3.5.1.89
Alternative name(s):
Phosphatidylinositol-glycan biosynthesis class L protein
Short name=PIG-L
Gene names
Name:pigl
ORF Names:DDB_G0293136
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length258 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol By similarity.

Catalytic activity

6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O = 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate.

Pathway

Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.

Subcellular location

Endoplasmic reticulum membrane By similarity.

Sequence similarities

Belongs to the PIGL family.

Ontologies

Keywords
   Biological processGPI-anchor biosynthesis
   Cellular componentEndoplasmic reticulum
Membrane
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processGPI anchor biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentendoplasmic reticulum membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionN-acetylglucosaminylphosphatidylinositol deacetylase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 258258Probable N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
PRO_0000328582

Regions

Compositional bias148 – 16720Ser-rich

Sequences

Sequence LengthMass (Da)Tools
Q54C64 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: C83B099E30F24125

FASTA25829,237
        10         20         30         40         50         60 
MKNHLNNNED NSTLIKKKVL FVIAHPDDEC MFFTPTIQHY NFIGSEIFVA CLSNGNAVGL 

        70         80         90        100        110        120 
GKIREKELID SCIDMGINQE NVFFDQTNNF QDGMNIIWDT DLVEKTILSF IKQTSADIVI 

       130        140        150        160        170        180 
SFDECGISSH PNHISISNGL KQLMKNKSSS TTTTSTTSSS SSSSSLSNRT TNNLNKEIKA 

       190        200        210        220        230        240 
YKLETVNIIR KYIGIADIPL TKLLSYDENS TQTFISTQLF PPSSYSPMTK HKSQFVWFRY 

       250 
LFVFLSRYSF INTLIEIK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000199 Genomic DNA. Translation: EAL60920.1.

3D structure databases

ProteinModelPortalQ54C64.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING44689.DDBDRAFT_0191808.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0235227; DDB0235227; DDB_G0293136.
KEGGddi:DDB_G0293136.

Organism-specific databases

dictyBaseDDB_G0293136. pigL.

Phylogenomic databases

eggNOGCOG2120.
KOK03434.
OMAHTQDVLF.
PhylomeDBQ54C64.

Enzyme and pathway databases

UniPathwayUPA00196.

Family and domain databases

Gene3D3.40.50.10320. 1 hit.
InterProIPR003737. GlcNAc_PI_deacetylase-related.
IPR024078. LmbE-like_dom.
[Graphical view]
PANTHERPTHR12993. PTHR12993. 1 hit.
PfamPF02585. PIG-L. 1 hit.
[Graphical view]
SUPFAMSSF102588. SSF102588. 1 hit.
ProtoNetSearch...

Other

PROQ54C64.

Entry information

Entry namePIGL_DICDI
AccessionPrimary (citable) accession number: Q54C64
Entry history
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: May 24, 2005
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase