SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q54B37

- GXCJ_DICDI

UniProt

Q54B37 - GXCJ_DICDI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

RhoGEF domain-containing protein gxcJ

Gene
gxcJ, DDB_0233315
Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

GTPase-activating protein By similarity.

GO - Molecular functioni

  1. Rho guanyl-nucleotide exchange factor activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Guanine-nucleotide releasing factor

Enzyme and pathway databases

ReactomeiREACT_204273. Rho GTPase cycle.
REACT_204470. PPARA activates gene expression.
REACT_211603. NRAGE signals death through JNK.

Names & Taxonomyi

Protein namesi
Recommended name:
RhoGEF domain-containing protein gxcJ
Gene namesi
Name:gxcJ
ORF Names:DDB_0233315
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 6, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0293978. gxcJ.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11551155RhoGEF domain-containing protein gxcJPRO_0000377437Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB_0233315.

Structurei

3D structure databases

ProteinModelPortaliQ54B37.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini700 – 874175DHAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili192 – 25766 Reviewed predictionAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi119 – 15335Poly-AsnAdd
BLAST
Compositional biasi172 – 1754Poly-Asn
Compositional biasi282 – 30322Poly-AsnAdd
BLAST
Compositional biasi434 – 4407Poly-Pro
Compositional biasi444 – 4496Poly-Ser
Compositional biasi491 – 4966Poly-Ser
Compositional biasi497 – 50913Poly-ThrAdd
BLAST
Compositional biasi610 – 6189Poly-Asn
Compositional biasi631 – 6377Poly-Asn
Compositional biasi652 – 66110Poly-Gln
Compositional biasi680 – 6889Poly-Thr
Compositional biasi1017 – 102610Poly-Ser
Compositional biasi1047 – 106014Poly-AsnAdd
BLAST
Compositional biasi1128 – 113710Poly-Gln

Sequence similaritiesi

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG3519.
InParanoidiQ54B37.
OMAiSTINCIN.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
InterProiIPR000219. DH-domain.
[Graphical view]
PfamiPF00621. RhoGEF. 1 hit.
[Graphical view]
SMARTiSM00325. RhoGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
PROSITEiPS50010. DH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q54B37-1 [UniParc]FASTAAdd to Basket

« Hide

MLIHPFIQSF TEIIDNRMKL GNNMEGVIEC KNCQTDTPKC NKVCLTCNSD     50
IGERCWRCNY LGKINSKFCF RCNVKLHPTS IPPKDSIQPI PIFTKHPIAS 100
TLLINKSIIP TQSENNSIND NNNNNNNNNN NNNNNNNNNN NNNNNNNNNT 150
NNNDSKIIDA TITNTKNNNT TNNNNISNNN SSNIISNSNN NNNNNNNNNN 200
NNNNNNNNNN NLNFLKKSTS CDNGSFESIS DSISPIKDII NNINNRTKDI 250
EKLNSALPLN KKSNSSTSWS NFNTFKNNSK TNNNNNNNNN NNNNNNNNNN 300
NNNYKPTITS SQTQPSLMEN SKDIDKKEKI PSNINNNRST TIIYKYQEDN 350
SEDYTDDGDF EEFQINSNLT SESSSIDSLI IKDGVIATTV TSSTINCIND 400
NNFDPDQLSS STSSIKKPKL FYSITKKKLV SQSPPPPQPP FLASASSSST 450
TTITTTDSLE KSIKDSTPIA TTLVNDYQNQ NQNLNNESAA SSSSLSTTTT 500
TTTTTTTTTL LPDSQTNLNN LIFIEKLNND LSGSIETLNN SLNNSLNSLN 550
SSFNFRLNLN SITNNEDKRL SNSSLLDEII DAFPSPPSKN PYISVLNTSG 600
GIGSNSNSSN NNNSNSNNIT NSNSSSFSKK NSNNNNNYQP VISLPIPIVN 650
HQQQQQQQQL QTAAILGNNN INFIQNPSST STTTTTTTAS TTTILIKSDH 700
RTNLIKEILT TELDYVNDLE TIINVFCKPL RDFISNEDSA SIFSNIEQIW 750
QINKQLYENL ISNTLTIGQV FSNMSDSLKV YSVYCNYHQK SLDSLNQLLK 800
TPQNESFFDQ LLSKPELRGM GPHSFLIKPV QRICKYPLLL KELLKATAED 850
HFDYPQLILA VEKIEKIVGT INSQKKEMET WQRTMQLIQN LKGADNLQLL 900
AANRHLILEG SLHLVIGFTE NAEKKNSSLK FKKGVYFLFN DLFLFTKQKG 950
TTYKLLFYTQ LDNVLIHANV SNCFPADKSV FSLVEIGVGG RKWTFCNTNS 1000
NSSNISNSGN SSGIINSSSS SSGSCSNGGN SSGYNNLNNT CGIYSGNSNN 1050
NNNNNNNNNN IFSTIQKLIE KTWEDKFMGQ SSVSHRLSIP STSSPNNGAS 1100
LNGNSSSNSS STSISTVGSP NVTSAAKQQQ QLQQQQQSSK KRNRRLVKSL 1150
VNIKT 1155
Length:1,155
Mass (Da):127,930
Last modified:May 24, 2005 - v1
Checksum:iBC01765B3D694494
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000224 Genomic DNA. Translation: EAL60488.1.
RefSeqiXP_628879.1. XM_628877.1.

Genome annotation databases

EnsemblProtistsiDDB0233315; DDB0233315; DDB_G0293978.
GeneIDi8629495.
KEGGiddi:DDB_G0293978.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAFI02000224 Genomic DNA. Translation: EAL60488.1 .
RefSeqi XP_628879.1. XM_628877.1.

3D structure databases

ProteinModelPortali Q54B37.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 44689.DDB_0233315.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0233315 ; DDB0233315 ; DDB_G0293978 .
GeneIDi 8629495.
KEGGi ddi:DDB_G0293978.

Organism-specific databases

dictyBasei DDB_G0293978. gxcJ.

Phylogenomic databases

eggNOGi KOG3519.
InParanoidi Q54B37.
OMAi STINCIN.

Enzyme and pathway databases

Reactomei REACT_204273. Rho GTPase cycle.
REACT_204470. PPARA activates gene expression.
REACT_211603. NRAGE signals death through JNK.

Family and domain databases

Gene3Di 1.20.900.10. 1 hit.
InterProi IPR000219. DH-domain.
[Graphical view ]
Pfami PF00621. RhoGEF. 1 hit.
[Graphical view ]
SMARTi SM00325. RhoGEF. 1 hit.
[Graphical view ]
SUPFAMi SSF48065. SSF48065. 1 hit.
PROSITEi PS50010. DH_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiGXCJ_DICDI
AccessioniPrimary (citable) accession number: Q54B37
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: May 24, 2005
Last modified: September 3, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3