ID   Q54AD6_9CALI            Unreviewed;       535 AA.
AC   Q54AD6;
DT   24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT   24-MAY-2005, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=VP1 protein {ECO:0000313|EMBL:BAD20208.1};
OS   Norwalk-like virus.
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
OX   NCBI_TaxID=95340 {ECO:0000313|EMBL:BAD20208.1, ECO:0000313|Proteomes:UP000136094};
RN   [1] {ECO:0000313|EMBL:BAD20208.1, ECO:0000313|Proteomes:UP000136094}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hu/Norovirus/hiroshima/1999/JP {ECO:0000313|EMBL:BAD20208.1};
RX   PubMed=15593412; DOI=10.1007/s00705-004-0345-4;
RA   Hansman G.S., Doan L.T., Kguyen T.A., Okitsu S., Katayama K., Ogawa S.,
RA   Natori K., Takeda N., Kato Y., Nishio O., Noda M., Ushijima H.;
RT   "Detection of norovirus and sapovirus infection among children with
RT   gastroenteritis in Ho Chi Minh City, Vietnam.";
RL   Arch. Virol. 149:1673-1688(2004).
RN   [2] {ECO:0007829|PDB:3R6J, ECO:0007829|PDB:3R6K}
RP   X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) OF 225-525 IN COMPLEX WITH FUCOSE
RP   AND ALPHA-D-GALACTOSE.
RX   PubMed=21525337; DOI=10.1128/JVI.00246-11;
RA   Hansman G.S., Biertumpfel C., Georgiev I., McLellan J.S., Chen L., Zhou T.,
RA   Katayama K., Kwong P.D.;
RT   "Crystal structures of GII.10 and GII.12 norovirus protruding domains in
RT   complex with histo-blood group antigens reveal details for a potential site
RT   of vulnerability.";
RL   J. Virol. 85:6687-6701(2011).
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DR   EMBL; AB044366; BAD20208.1; -; Genomic_RNA.
DR   RefSeq; YP_009237898.1; NC_029646.1.
DR   PDB; 3R6J; X-ray; 1.75 A; A=224-525.
DR   PDB; 3R6K; X-ray; 1.60 A; A=225-525.
DR   PDBsum; 3R6J; -.
DR   PDBsum; 3R6K; -.
DR   SMR; Q54AD6; -.
DR   UniLectin; Q54AD6; -.
DR   GeneID; 27042432; -.
DR   KEGG; vg:27042432; -.
DR   OrthoDB; 3540at10239; -.
DR   Proteomes; UP000136094; Genome.
DR   CDD; cd00205; rhv_like; 1.
DR   Gene3D; 2.60.120.20; -; 1.
DR   Gene3D; 2.40.30.120; Positive stranded ssRNA viruses; 1.
DR   Gene3D; 2.40.510.10; Positive stranded ssRNA viruses; 1.
DR   InterPro; IPR004005; Calicivirus_coat.
DR   InterPro; IPR013643; Calicivirus_coat_C.
DR   InterPro; IPR033703; Rhv-like.
DR   InterPro; IPR029053; Viral_coat.
DR   Pfam; PF00915; Calici_coat; 1.
DR   Pfam; PF08435; Calici_coat_C; 1.
DR   SUPFAM; SSF88633; Positive stranded ssRNA viruses; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:3R6J, ECO:0007829|PDB:3R6K}.
FT   DOMAIN          12..275
FT                   /note="Calicivirus coat protein"
FT                   /evidence="ECO:0000259|Pfam:PF00915"
FT   DOMAIN          305..533
FT                   /note="Calicivirus coat protein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08435"
SQ   SEQUENCE   535 AA;  58450 MW;  02B77FFB68B7B158 CRC64;
     MKMASSDAAP SNDGAAGLVP EANNETMALE PVAGASIAAP LTGQNNIIDP WIRLNFVQAP
     NGEFTVSPRN SPGEVLLNLE LGPELNPYLA HLSRMYNGYA GGVEVQVLLA GNAFTAGKLV
     FAAVPPHFPL ENISPGQITM FPHVIIDVRT LEPVLLPLPD VRNNFFHYNQ QNEPRMRLVA
     MLYTPLRSNG SGDDVFTVSC RVLTRPSPDF DFNYLVPPTV ESKTKPFTLP ILTIGELTNS
     RFPVPIDELY TSPNESLVVQ PQNGRCALDG ELQGTTQLLP TAICSFRGRI NQKVSGENHV
     WNMQVTNING TPFDPTEDVP APLGTPDFSG KLFGVLSQRD HDNACRSHDA VIATNSAKFT
     PKLGAIQIGT WEEDDVHINQ PTKFTPVGLF EDGGFNQWTL PNYSGALTLN MGLAPPVAPT
     FPGEQILFFR SHIPLKGGVA DPVIDCLLPQ EWIQHLYQES APSQSDVALI RFTNPDTGRV
     LFEAKLHRSG YITVANTGSR PIVVPANGYF RFDSWVNQFY SLAPMGTGNG RRRVQ
//