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Q54AA6

- Q54AA6_MOUSE

UniProt

Q54AA6 - Q54AA6_MOUSE

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Protein

O-acyltransferase

Gene

Dgat1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. 2-acylglycerol O-acyltransferase activity Source: MGI
  2. diacylglycerol O-acyltransferase activity Source: MGI

GO - Biological processi

  1. triglyceride biosynthetic process Source: MGI
  2. very-low-density lipoprotein particle assembly Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
O-acyltransferaseUniRule annotation
Gene namesi
Name:Dgat1Imported
Synonyms:DgatImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1333825. Dgat1.

Subcellular locationi

Endoplasmic reticulum membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

GO - Cellular componenti

  1. endoplasmic reticulum membrane Source: UniProtKB-SubCell
  2. integral component of membrane Source: UniProtKB-KW
  3. membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ54AA6.

Expressioni

Gene expression databases

BgeeiQ54AA6.
ExpressionAtlasiQ54AA6. baseline and differential.
GenevestigatoriQ54AA6.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliQ54AA6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOVERGENiHBG051341.
KOiK11155.
OMAiLWAFTAM.
PhylomeDBiQ54AA6.

Family and domain databases

InterProiIPR027251. Diacylglycerol_acylTrfase1.
IPR004299. MBOAT_fam.
IPR014371. Oat_ACAT_DAG_ARE.
[Graphical view]
PANTHERiPTHR10408. PTHR10408. 1 hit.
PfamiPF03062. MBOAT. 1 hit.
[Graphical view]
PIRSFiPIRSF000439. Oat_ACAT_DAG_ARE. 1 hit.
PIRSF500231. Oat_dag. 1 hit.

Sequencei

Sequence statusi: Complete.

Q54AA6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGDRGGAGSS RRRRTGSRVS VQGGSGPKVE EDEVRDAAVS PDLGAGGDAP
60 70 80 90 100
APAPAPAHTR DKDGRTSVGD GYWDLRCHRL QDSLFSSDSG FSNYRGILNW
110 120 130 140 150
CVVMLILSNA RLFLENLIKY GILVDPIQVV SLFLKDPYSW PAPCVIIASN
160 170 180 190 200
IFVVAAFQIE KRLAVGALTE QMGLLLHVVN LATIICFPAA VALLVESITP
210 220 230 240 250
VGSVFALASY SIMFLKLYSY RDVNLWCRQR RVKAKAVSTG KKVSGAAAQQ
260 270 280 290 300
AVSYPDNLTY RDLYYFIFAP TLCYELNFPR SPRIRKRFLL RRVLEMLFFT
310 320 330 340 350
QLQVGLIQQW MVPTIQNSMK PFKDMDYSRI IERLLKLAVP NHLIWLIFFY
360 370 380 390 400
WFFHSCLNAV AELLQFGDRE FYRDWWNAES VTYFWQNWNI PVHKWCIRHF
410 420 430 440 450
YKPMLRHGSS KWVARTGVFL TSAFFHEYLV SVPLRMFRLW AFTAMMAQVP
460 470 480 490
LAWIVGRFFQ GNYGNAAVWV TLIIGQPVAV LMYVHDYYVL NYDAPVGV
Length:498
Mass (Da):56,790
Last modified:May 24, 2005 - v1
Checksum:iE7B0DD6DDCF1EC2B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB057816 mRNA. Translation: BAC66171.1.
RefSeqiNP_034176.1. NM_010046.2.
UniGeneiMm.22633.

Genome annotation databases

GeneIDi13350.
KEGGimmu:13350.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB057816 mRNA. Translation: BAC66171.1 .
RefSeqi NP_034176.1. NM_010046.2.
UniGenei Mm.22633.

3D structure databases

ProteinModelPortali Q54AA6.
ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi Q54AA6.

Proteomic databases

PRIDEi Q54AA6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 13350.
KEGGi mmu:13350.

Organism-specific databases

CTDi 8694.
MGIi MGI:1333825. Dgat1.

Phylogenomic databases

HOVERGENi HBG051341.
KOi K11155.
OMAi LWAFTAM.
PhylomeDBi Q54AA6.

Miscellaneous databases

NextBioi 283676.
SOURCEi Search...

Gene expression databases

Bgeei Q54AA6.
ExpressionAtlasi Q54AA6. baseline and differential.
Genevestigatori Q54AA6.

Family and domain databases

InterProi IPR027251. Diacylglycerol_acylTrfase1.
IPR004299. MBOAT_fam.
IPR014371. Oat_ACAT_DAG_ARE.
[Graphical view ]
PANTHERi PTHR10408. PTHR10408. 1 hit.
Pfami PF03062. MBOAT. 1 hit.
[Graphical view ]
PIRSFi PIRSF000439. Oat_ACAT_DAG_ARE. 1 hit.
PIRSF500231. Oat_dag. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Mus musculus diacylglycerol acyltransferase (Dgat) mRNA, complete cds."
    Yamasaki Y., Watanabe T.K., Tanigami A.
    Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ54AA6_MOUSE
AccessioniPrimary (citable) accession number: Q54AA6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 26, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)