Q54AA6 (Q54AA6_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
O-acyltransferase PIRNR PIRNR000439

Gene names

Name:	Dgat1 MGI 1333825
Synonyms:	Dgat EMBL BAC66171.1

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	498 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Endoplasmic reticulum membrane; Multi-pass membrane protein By similarity PIRNR PIRNR000439.
Sequence similarities	Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily. PIRNR PIRNR000439

Ontologies

Keywords
Cellular component	Endoplasmic reticulum PIRNR PIRNR000439 Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS004299
Molecular function	Acyltransferase PIRNR PIRNR000439 EMBL BAC66171.1 Transferase
Gene Ontology (GO)
Biological_process	triglyceride biosynthetic process Inferred from electronic annotation. Source: Compara very-low-density lipoprotein particle assembly Inferred from electronic annotation. Source: Compara
Cellular_component	endoplasmic reticulum membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW membrane Inferred from direct assay PubMed 12077311. Source: MGI
Molecular_function	2-acylglycerol O-acyltransferase activity Inferred from direct assay PubMed 12077311. Source: MGI diacylglycerol O-acyltransferase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q54AA6 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: E7B0DD6DDCF1EC2B	FASTA	498	56,790
	10 20 30 40 50 60 MGDRGGAGSS RRRRTGSRVS VQGGSGPKVE EDEVRDAAVS PDLGAGGDAP APAPAPAHTR 70 80 90 100 110 120 DKDGRTSVGD GYWDLRCHRL QDSLFSSDSG FSNYRGILNW CVVMLILSNA RLFLENLIKY 130 140 150 160 170 180 GILVDPIQVV SLFLKDPYSW PAPCVIIASN IFVVAAFQIE KRLAVGALTE QMGLLLHVVN 190 200 210 220 230 240 LATIICFPAA VALLVESITP VGSVFALASY SIMFLKLYSY RDVNLWCRQR RVKAKAVSTG 250 260 270 280 290 300 KKVSGAAAQQ AVSYPDNLTY RDLYYFIFAP TLCYELNFPR SPRIRKRFLL RRVLEMLFFT 310 320 330 340 350 360 QLQVGLIQQW MVPTIQNSMK PFKDMDYSRI IERLLKLAVP NHLIWLIFFY WFFHSCLNAV 370 380 390 400 410 420 AELLQFGDRE FYRDWWNAES VTYFWQNWNI PVHKWCIRHF YKPMLRHGSS KWVARTGVFL 430 440 450 460 470 480 TSAFFHEYLV SVPLRMFRLW AFTAMMAQVP LAWIVGRFFQ GNYGNAAVWV TLIIGQPVAV 490 LMYVHDYYVL NYDAPVGV

References

[1]	"Mus musculus diacylglycerol acyltransferase (Dgat) mRNA, complete cds." Yamasaki Y., Watanabe T.K., Tanigami A. Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB057816 mRNA. Translation: BAC66171.1.
IPI	IPI00130963.
RefSeq	NP_034176.1. NM_010046.2.
UniGene	Mm.22633.
3D structure databases
ProteinModelPortal	Q54AA6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q54AA6.
Proteomic databases
PRIDE	Q54AA6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	13350.
KEGG	mmu:13350.
UCSC	uc007wkn.1. mouse.
Organism-specific databases
CTD	8694.
MGI	MGI:1333825. Dgat1.
Phylogenomic databases
HOVERGEN	HBG051341.
InParanoid	Q54AA6.
KO	K11155.
OMA	FSWSSGF.
Gene expression databases
ArrayExpress	Q54AA6.
Bgee	Q54AA6.
Genevestigator	Q54AA6.
Family and domain databases
InterPro	IPR027251. Diacylglycerol_acylTrfase1. IPR004299. MBOAT_fam. IPR014371. Oat_ACAT_DAG_ARE. [Graphical view]
PANTHER	PTHR10408. PTHR10408. 1 hit.
Pfam	PF03062. MBOAT. 1 hit. [Graphical view]
PIRSF	PIRSF000439. Oat_ACAT_DAG_ARE. 1 hit. PIRSF500231. Oat_dag. 1 hit.
ProtoNet	Search...
Other
BindingDB	Q54AA6.
ChiTaRS	DGAT1. mouse.
NextBio	283676.
SOURCE	Search...

Entry information

Entry name

Q54AA6_MOUSE

Accession

Primary (citable) accession number: Q54AA6

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	April 3, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)