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Q54AA6

- Q54AA6_MOUSE

UniProt

Q54AA6 - Q54AA6_MOUSE

Protein

O-acyltransferase

Gene

Dgat1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 2-acylglycerol O-acyltransferase activity Source: MGI
    2. diacylglycerol O-acyltransferase activity Source: MGI

    GO - Biological processi

    1. triglyceride biosynthetic process Source: MGI
    2. very-low-density lipoprotein particle assembly Source: Ensembl

    Keywords - Molecular functioni

    AcyltransferaseUniRule annotationImported, Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    O-acyltransferaseUniRule annotation
    Gene namesi
    Name:Dgat1Imported
    Synonyms:DgatImported
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:1333825. Dgat1.

    Subcellular locationi

    Endoplasmic reticulum membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. endoplasmic reticulum membrane Source: UniProtKB-SubCell
    2. integral component of membrane Source: UniProtKB-KW
    3. membrane Source: MGI

    Keywords - Cellular componenti

    Endoplasmic reticulumUniRule annotation, Membrane

    PTM / Processingi

    Proteomic databases

    PRIDEiQ54AA6.

    Expressioni

    Gene expression databases

    ArrayExpressiQ54AA6.
    BgeeiQ54AA6.
    GenevestigatoriQ54AA6.

    Interactioni

    Structurei

    3D structure databases

    ProteinModelPortaliQ54AA6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    HOVERGENiHBG051341.
    InParanoidiQ54AA6.
    KOiK11155.
    OMAiLWAFTAM.
    PhylomeDBiQ54AA6.

    Family and domain databases

    InterProiIPR027251. Diacylglycerol_acylTrfase1.
    IPR004299. MBOAT_fam.
    IPR014371. Oat_ACAT_DAG_ARE.
    [Graphical view]
    PANTHERiPTHR10408. PTHR10408. 1 hit.
    PfamiPF03062. MBOAT. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000439. Oat_ACAT_DAG_ARE. 1 hit.
    PIRSF500231. Oat_dag. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q54AA6-1 [UniParc]FASTAAdd to Basket

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    MGDRGGAGSS RRRRTGSRVS VQGGSGPKVE EDEVRDAAVS PDLGAGGDAP    50
    APAPAPAHTR DKDGRTSVGD GYWDLRCHRL QDSLFSSDSG FSNYRGILNW 100
    CVVMLILSNA RLFLENLIKY GILVDPIQVV SLFLKDPYSW PAPCVIIASN 150
    IFVVAAFQIE KRLAVGALTE QMGLLLHVVN LATIICFPAA VALLVESITP 200
    VGSVFALASY SIMFLKLYSY RDVNLWCRQR RVKAKAVSTG KKVSGAAAQQ 250
    AVSYPDNLTY RDLYYFIFAP TLCYELNFPR SPRIRKRFLL RRVLEMLFFT 300
    QLQVGLIQQW MVPTIQNSMK PFKDMDYSRI IERLLKLAVP NHLIWLIFFY 350
    WFFHSCLNAV AELLQFGDRE FYRDWWNAES VTYFWQNWNI PVHKWCIRHF 400
    YKPMLRHGSS KWVARTGVFL TSAFFHEYLV SVPLRMFRLW AFTAMMAQVP 450
    LAWIVGRFFQ GNYGNAAVWV TLIIGQPVAV LMYVHDYYVL NYDAPVGV 498
    Length:498
    Mass (Da):56,790
    Last modified:May 24, 2005 - v1
    Checksum:iE7B0DD6DDCF1EC2B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB057816 mRNA. Translation: BAC66171.1.
    RefSeqiNP_034176.1. NM_010046.2.
    UniGeneiMm.22633.

    Genome annotation databases

    GeneIDi13350.
    KEGGimmu:13350.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB057816 mRNA. Translation: BAC66171.1 .
    RefSeqi NP_034176.1. NM_010046.2.
    UniGenei Mm.22633.

    3D structure databases

    ProteinModelPortali Q54AA6.
    ModBasei Search...
    MobiDBi Search...

    Chemistry

    BindingDBi Q54AA6.

    Proteomic databases

    PRIDEi Q54AA6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 13350.
    KEGGi mmu:13350.

    Organism-specific databases

    CTDi 8694.
    MGIi MGI:1333825. Dgat1.

    Phylogenomic databases

    HOVERGENi HBG051341.
    InParanoidi Q54AA6.
    KOi K11155.
    OMAi LWAFTAM.
    PhylomeDBi Q54AA6.

    Miscellaneous databases

    ChiTaRSi DGAT1. mouse.
    NextBioi 283676.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q54AA6.
    Bgeei Q54AA6.
    Genevestigatori Q54AA6.

    Family and domain databases

    InterProi IPR027251. Diacylglycerol_acylTrfase1.
    IPR004299. MBOAT_fam.
    IPR014371. Oat_ACAT_DAG_ARE.
    [Graphical view ]
    PANTHERi PTHR10408. PTHR10408. 1 hit.
    Pfami PF03062. MBOAT. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000439. Oat_ACAT_DAG_ARE. 1 hit.
    PIRSF500231. Oat_dag. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Mus musculus diacylglycerol acyltransferase (Dgat) mRNA, complete cds."
      Yamasaki Y., Watanabe T.K., Tanigami A.
      Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ54AA6_MOUSE
    AccessioniPrimary (citable) accession number: Q54AA6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 24, 2005
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)