Q54A98 (Q54A98_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Receptor activator of nuclear factor kappa B ligand 3 EMBL BAB79693.1

Submitted name:
Tumor necrosis factor (Ligand) superfamily, member 11 EMBL CAM23721.1
Submitted name:
Tumor necrosis factor (Ligand) superfamily, member 11, isoform CRA_b EMBL EAX08680.1

Gene names

Name:	hRANKL 3 EMBL BAB79693.1
Synonyms:	TNFSF11 EMBL CAM23721.1
ORF Names:	hCG_32838 EMBL EAX08680.1, RP11-86N24.2-002 EMBL CAM23721.1

Organism

Homo sapiens (Human) EMBL BAB79693.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	244 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Receptor EMBL BAB79693.1
Gene Ontology (GO)
Biological process	immune response Inferred from electronic annotation. Source: InterPro
Cellular component	membrane Inferred from electronic annotation. Source: InterPro
Molecular function	receptor activity Inferred from electronic annotation. Source: UniProtKB-KW tumor necrosis factor receptor binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q54A98 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: C827590684B6B83C	FASTA	244	27,690
	10 20 30 40 50 60 MDPNRISEDG THCIYRILRL HENADFQDTT LESQDTKLIP DSCRRIKQAF QGAVQKELQH 70 80 90 100 110 120 IVGSQHIRAE KAMVDGSWLD LAKRSKLEAQ PFAHLTINAT DIPSGSHKVS LSSWYHDRGW 130 140 150 160 170 180 AKISNMTFSN GKLIVNQDGF YYLYANICFR HHETSGDLAT EYLQLMVYVT KTSIKIPSSH 190 200 210 220 230 240 TLMKGGSTKY WSGNSEFHFY SINVGGFFKL RSGEEISIEV SNPSLLDPDQ DATYFGAFKV RDID

References

[1]	"Regulation of osteoclastogenesis by three human RANKL isoforms expressed in NIH3T3 cells." Suzuki J., Ikeda T., Kuroyama H., Seki S., Kasai M., Utsuyama M., Tatsumi M., Uematsu H., Hirokawa K. Biochem. Biophys. Res. Commun. 314:1021-1027(2004) [PubMed: 14751235] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Pelan S. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB064268 mRNA. Translation: BAB79693.1. AL139382 Genomic DNA. Translation: CAM23721.1. CH471075 Genomic DNA. Translation: EAX08680.1.
IPI	IPI00219810.
RefSeq	NP_143026.1. NM_033012.3.
UniGene	Hs.333791.
3D structure databases
ProteinModelPortal	Q54A98.
SMR	Q54A98. Positions 89-244.
ModBase	Search...
Protein-protein interaction databases
STRING	Q54A98.
Proteomic databases
PRIDE	Q54A98.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000544862; ENSP00000444913; ENSG00000120659.
GeneID	8600.
KEGG	hsa:8600.
UCSC	uc001uyt.1. human.
Organism-specific databases
CTD	8600.
Phylogenomic databases
GeneTree	ENSGT00530000063443.
HOVERGEN	HBG054257.
OrthoDB	EOG4FTW12.
Gene expression databases
ArrayExpress	Q54A98.
Bgee	Q54A98.
Family and domain databases
InterPro	IPR006052. TNF. IPR008983. Tumour_necrosis_fac-like. [Graphical view]
Gene3D	G3DSA:2.60.120.40. Tumour_necrosis_fac-like. 1 hit.
KO	K05473.
Pfam	PF00229. TNF. 1 hit. [Graphical view]
SMART	SM00207. TNF. 1 hit. [Graphical view]
SUPFAM	SSF49842. TNF_like. 1 hit.
PROSITE	PS50049. TNF_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	32221.
PMAP-CutDB	Q54A98.

Entry information

Entry name

Q54A98_HUMAN

Accession

Primary (citable) accession number: Q54A98

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	January 25, 2012
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.