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Protein

AP complex subunit sigma

Gene

AP1S2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Biological processProtein transportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
AP complex subunit sigmaUniRule annotation
Gene namesi
Name:AP1S2Imported
ORF Names:hCG_1982256Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000182287.13

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneUniRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24851

PTM / Processingi

Proteomic databases

MaxQBiQ549M9

Expressioni

Gene expression databases

BgeeiENSG00000182287
ExpressionAtlasiQ549M9 baseline and differential

Structurei

3D structure databases

SMRiQ549M9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 139Clat_adaptor_sInterPro annotationAdd BLAST139

Sequence similaritiesi

Belongs to the adaptor complexes small subunit family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0934 Eukaryota
COG5030 LUCA
HOVERGENiHBG050517
KOiK12394

Family and domain databases

InterProiView protein in InterPro
IPR016635 AP_complex_ssu
IPR022775 AP_mu_sigma_su
IPR000804 Clathrin_sm-chain_CS
IPR011012 Longin-like_dom_sf
PANTHERiPTHR11753 PTHR11753, 1 hit
PfamiView protein in Pfam
PF01217 Clat_adaptor_s, 1 hit
PIRSFiPIRSF015588 AP_complex_sigma, 1 hit
SUPFAMiSSF64356 SSF64356, 1 hit
PROSITEiView protein in PROSITE
PS00989 CLAT_ADAPTOR_S, 1 hit

Sequencei

Sequence statusi: Complete.

Q549M9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQFMLLFSRQ GKLRLQKWYV PLSDKEKKKI TRELVQTVLA RKPKMCSFLE
60 70 80 90 100
WRDLKIVYKR YASLYFCCAI EDQDNELITL EIIHRYVELL DKYFGSVCEL
110 120 130 140 150
DIIFNFEKAY FILDEFLLGG EVQETSKKNV LKAIEQADLL QEEAETPRSV

LEEIGLT
Length:157
Mass (Da):18,615
Last modified:May 24, 2005 - v1
Checksum:iDD9F59119909D89C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF087876 mRNA Translation: AAP97176.1
CH471074 Genomic DNA Translation: EAW98908.1
RefSeqiNP_003907.3, NM_003916.4
UniGeneiHs.121592

Genome annotation databases

GeneIDi8905
KEGGihsa:8905
UCSCiuc004cxi.5 human

Similar proteinsi

Entry informationi

Entry nameiQ549M9_HUMAN
AccessioniPrimary (citable) accession number: Q549M9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: May 23, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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