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Protein
Submitted name:

Uncoupling protein 2 (Mitochondrial, proton carrier), isoform CRA_a

Gene

Ucp2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Biological processTransportUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncoupling protein 2 (Mitochondrial, proton carrier), isoform CRA_aImported
Submitted name:
Uncoupling protein-2Imported
Gene namesi
Name:Ucp2Imported
Synonyms:UCP2Imported
ORF Names:mCG_2855Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:109354 Ucp2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000033685

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati11 – 106SolcarPROSITE-ProRule annotationAdd BLAST96
Repeati114 – 203SolcarPROSITE-ProRule annotationAdd BLAST90
Repeati212 – 297SolcarPROSITE-ProRule annotationAdd BLAST86

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG0753 Eukaryota
ENOG410XRV1 LUCA
HOGENOMiHOG000165140
HOVERGENiHBG009528
KOiK15103
OMAiSEHAGIG
OrthoDBiEOG091G0BQ7

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR002030 Mit_uncoupling_UCP-like
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
PRINTSiPR00784 MTUNCOUPLING
SUPFAMiSSF103506 SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

Q549J5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGFKATDVP PTATVKFLGA GTAACIADLI TFPLDTAKVR LQIQGESQGL
60 70 80 90 100
VRTAASAQYR GVLGTILTMV RTEGPRSLYN GLVAGLQRQM SFASVRIGLY
110 120 130 140 150
DSVKQFYTKG SEHAGIGSRL LAGSTTGALA VAVAQPTDVV KVRFQAQARA
160 170 180 190 200
GGGRRYQSTV EAYKTIAREE GIRGLWKGTS PNVARNAIVN CAELVTYDLI
210 220 230 240 250
KDTLLKANLM TDDLPCHFTS AFGAGFCTTV IASPVDVVKT RYMNSALGQY
260 270 280 290 300
HSAGHCALTM LRKEGPRAFY KGFMPSFLRL GSWNVVMFVT YEQLKRALMA

AYQSREAPF
Length:309
Mass (Da):33,374
Last modified:May 24, 2005 - v1
Checksum:i329794EEA99810E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF111998 mRNA Translation: AAD17198.1
AF096288 Genomic DNA Translation: AAD21150.1
AK054060 mRNA Translation: BAC35641.1
AK134116 mRNA Translation: BAE22021.1
AK142687 mRNA Translation: BAE25160.1
CH466531 Genomic DNA Translation: EDL16447.1
CH466531 Genomic DNA Translation: EDL16449.1
CH466531 Genomic DNA Translation: EDL16451.1
CH466531 Genomic DNA Translation: EDL16452.1
RefSeqiNP_035801.3, NM_011671.5
XP_006507642.1, XM_006507579.2
UniGeneiMm.171378

Genome annotation databases

GeneIDi22228
KEGGimmu:22228

Similar proteinsi

Entry informationi

Entry nameiQ549J5_MOUSE
AccessioniPrimary (citable) accession number: Q549J5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: March 28, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health