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Protein

cAMP-dependent protein kinase inhibitor

Gene

PKIG

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei16Important for inhibitionUniRule annotation1
Sitei19Important for inhibitionUniRule annotation1
Sitei20Important for inhibitionUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Protein kinase inhibitorUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
cAMP-dependent protein kinase inhibitorUniRule annotation
Gene namesi
Name:PKIGImported
ORF Names:hCG_38104Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33351.

Expressioni

Gene expression databases

BgeeiENSG00000168734.
ExpressionAtlasiQ549H9. baseline and differential.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
MEOX2P502223EBI-10243311,EBI-748397

Protein-protein interaction databases

IntActiQ549H9. 1 interactor.

Structurei

3D structure databases

SMRiQ549H9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PKI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410J1ME. Eukaryota.
ENOG410ZDGT. LUCA.
HOVERGENiHBG104492.
OMAiTDFISCD.
OrthoDBiEOG091G13WE.

Family and domain databases

InterProiView protein in InterPro
IPR004171. cAMP_dep_PKI.
PfamiView protein in Pfam
PF02827. PKI. 1 hit.
PIRSFiPIRSF001667. PKI. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD010366. cAMP_dep_PKI. 1 hit.

Sequencei

Sequence statusi: Complete.

Q549H9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMEVESSYSD FISCDRTGRR NAVPDIQGDS EAVSVRKLAG DMGELALEGA
60 70
EGQVEGSAPD KEAGNQPQSS DGTTSS
Length:76
Mass (Da):7,910
Last modified:May 24, 2005 - v1
Checksum:iF01B4C73ED2CC6EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC104256 mRNA. Translation: AAI04257.1.
BC104257 mRNA. Translation: AAI04258.1.
AF115966 mRNA. Translation: AAP97238.1.
AK312048 mRNA. Translation: BAG34984.1.
CH471077 Genomic DNA. Translation: EAW75908.1.
CH471077 Genomic DNA. Translation: EAW75910.1.
CH471077 Genomic DNA. Translation: EAW75911.1.
CH471077 Genomic DNA. Translation: EAW75912.1.
CH471077 Genomic DNA. Translation: EAW75913.1.
CH471077 Genomic DNA. Translation: EAW75914.1.
RefSeqiNP_001268373.1. NM_001281444.1.
NP_001268374.1. NM_001281445.1.
NP_008997.1. NM_007066.4.
NP_861520.1. NM_181804.2.
NP_861521.1. NM_181805.2.
XP_016883103.1. XM_017027614.1.
XP_016883104.1. XM_017027615.1.
XP_016883105.1. XM_017027616.1.
UniGeneiHs.472831.

Genome annotation databases

GeneIDi11142.
KEGGihsa:11142.

Similar proteinsi

Entry informationi

Entry nameiQ549H9_HUMAN
AccessioniPrimary (citable) accession number: Q549H9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: August 30, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.