ID   Q549A5_MOUSE            Unreviewed;       448 AA.
AC   Q549A5;
DT   24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT   24-MAY-2005, sequence version 1.
DT   21-SEP-2011, entry version 41.
DE   RecName: Full=Clusterin;
DE   Flags: Precursor;
GN   Name=Clu;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=SvJ/129;
RA   Zhu G., Ley-Ebert C., Barrie A.M. III, Witte D.P., Rosenberg M.,
RA   Harmony J.A.K., Aronow B.J.;
RT   "Clusterin Gene Locus Structure and Function in Development,
RT   Homeostasis, and Tissue Injury.";
RL   (In) Landes R.G. (eds.);
RL   CLUSTERIN IN NORMAL BRAIN FUNCTIONS AND DURING NEURODEGENERATION.,
RL   pp.1-16, Springer-Verlag, Austin, TX (1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=SvJ/129;
RX   MEDLINE=20521683; PubMed=11067863; DOI=10.1172/JCI9037;
RA   McLaughlin L., Zhu G., Mistry M., Ley-Ebert C., Stuart W.D.,
RA   Florio C.J., Groen P.A., Witt S.A., Kimball T.R., Witte D.P.,
RA   Harmony J.A., Aronow B.J.;
RT   "Apolipoprotein J/clusterin limits the severity of murine autoimmune
RT   myocarditis.";
RL   J. Clin. Invest. 106:1105-1113(2000).
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=SvJ/129;
RA   Jordan-Starck T.C., Ley-Ebert C., Zhu G., Johnson J.A.,
RA   Harmony J.A.K., Aronow B.J.;
RL   Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Balb/c; TISSUE=Uterus;
RA   You K.H., Jeon J.H.;
RT   "Identification of Truncated SGP-2 Lacking a Signal Peptide for
RT   Secretion.";
RL   Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the clusterin family.
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DR   EMBL; AF182509; AAF06365.1; -; Genomic_DNA.
DR   EMBL; AF248057; AAF67184.1; -; mRNA.
DR   IPI; IPI00320420; -.
DR   RefSeq; NP_038520.2; NM_013492.2.
DR   UniGene; Mm.200608; -.
DR   ProteinModelPortal; Q549A5; -.
DR   STRING; Q549A5; -.
DR   PRIDE; Q549A5; -.
DR   GeneID; 12759; -.
DR   KEGG; mmu:12759; -.
DR   NMPDR; fig|10090.3.peg.29296; -.
DR   UCSC; uc007ujs.2; mouse.
DR   CTD; 1191; -.
DR   MGI; MGI:88423; Clu.
DR   HOVERGEN; HBG006908; -.
DR   InParanoid; Q549A5; -.
DR   OMA; NGDRIDS; -.
DR   PhylomeDB; Q549A5; -.
DR   ArrayExpress; Q549A5; -.
DR   Bgee; Q549A5; -.
DR   Genevestigator; Q549A5; -.
DR   GO; GO:0008219; P:cell death; IEA:InterPro.
DR   InterPro; IPR016016; Clusterin.
DR   InterPro; IPR000753; Clusterin-like.
DR   InterPro; IPR016015; Clusterin_C.
DR   InterPro; IPR016014; Clusterin_N.
DR   PANTHER; PTHR10970:SF1; Clusterin; 1.
DR   Pfam; PF01093; Clusterin; 1.
DR   PIRSF; PIRSF002368; Clusterin; 1.
DR   SMART; SM00035; CLa; 1.
DR   SMART; SM00030; CLb; 1.
DR   PROSITE; PS00492; CLUSTERIN_1; 1.
DR   PROSITE; PS00493; CLUSTERIN_2; 1.
PE   2: Evidence at transcript level;
KW   Signal.
FT   SIGNAL        1     17       Potential.
FT   CHAIN        18    448       Potential.
FT                                /FTId=PRO_5000057055.
SQ   SEQUENCE   448 AA;  51656 MW;  A860600A6F8D47F6 CRC64;
     MKILLLCVAL LLIWDNGMVL GEQEVSDNEL QELSTQGSRY INKEIQNAVQ GVKHIKTLIE
     KTNAERKSLL NSLEEAKKKK EDALEDTRDS EMKLKAFPEV CNETMMALWE ECKPCLKHTC
     MKFYARVCRS GSGLVGQQLE EFLNQSSPFY FWMNGDRIDS LLESDRQQSQ VLDAMQDSFA
     RASGIIDTLF QDRFFARELH DPHYFSPIGF PHKRPHFLYP KSRLVRSLMS PSHYGPPSFH
     NMFQPFFEMI HQAQQAMDVQ LHSPAFQFPD VDFLREGEDD RTVCKEIRRN STGCLKMKGQ
     CEKCQEILSV DCSTNNPAQA NLRQELNDSL QVAERLTEQY KELLQSFQSK MLNTSSLLEQ
     LNDQFNWVSQ LANLTQGEDK YYLRVSTVTT HSSDSEVPSR VTEVVVKLFD SDPITVVLPE
     EVSKDNPKFM DTVAEKALQE YRRKSRAE
//