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Protein
Submitted name:

Ketoreductase

Gene

frnP

Organism
Streptomyces roseofulvus
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
KetoreductaseImported
Gene namesi
Name:frnPImported
OrganismiStreptomyces roseofulvusImported
Taxonomic identifieri33902 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

Family & Domainsi

Sequence similaritiesi

Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q54998-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTAAPHTRP GEAGTTRGPA LVTGATRGIG LAVAEALVAR GYPVVVCARD
60 70 80 90 100
AEAVARTVKE LAAGGARVEG VVADVTDAAS VHELVATTVA RFGPVEVLVN
110 120 130 140 150
NAGRSGGGVT AELSESLWDD VIATNLKSVF LVTREVLTTG GMTGRGRGVV
160 170 180 190 200
NIASTGGKQG VVFGAPYSAS KHGVVGFTKA LGLELARSGI TVNAVCPGYV
210 220 230 240 250
ETPMAAGVRR HYADLWDVTE EDVLARFEAK IPLGRYTRPD EVAALVDYLV
260 270
TDAAAAVTAQ ALNVCGGLGN Y
Length:271
Mass (Da):27,673
Last modified:November 1, 1996 - v1
Checksum:iC7E5AFF0178F743F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L26338 Unassigned DNA. Translation: AAA19620.1.
AF058302 Genomic DNA. Translation: AAC18111.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L26338 Unassigned DNA. Translation: AAA19620.1.
AF058302 Genomic DNA. Translation: AAC18111.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin."
    Bibb M.J., Sherman D.H., Omura S., Hopwood D.A.
    Gene 142:31-39(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Analysis of a 27 kb region of Streptomyces roseofulvus containing genes for frenolicin biosynthesis."
    Reeves C.D., Soliday C.L.
    Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ54998_9ACTN
AccessioniPrimary (citable) accession number: Q54998
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 6, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.