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Protein
Submitted name:

Pristinamycin I synthase 2

Gene

snbC

Organism
Streptomyces pristinaespiralis
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Pristinamycin I synthase 2Imported
Gene namesi
Name:snbCImported
OrganismiStreptomyces pristinaespiralisImported
Taxonomic identifieri38300 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

Interactioni

Protein-protein interaction databases

STRINGi457429.SSDG_05434.

Structurei

3D structure databases

ProteinModelPortaliQ54959.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini955 – 102268Acyl carrierInterPro annotationAdd
BLAST
Domaini2012 – 207867Acyl carrierInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiCOG1020. LUCA.
KOiK16117.

Family and domain databases

Gene3Di1.10.1200.10. 2 hits.
InterProiIPR010071. AA_adenyl_domain.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
IPR001242. Condensatn.
IPR010060. NRPS_synth.
IPR020806. PKS_PP-bd.
IPR009081. PP-bd_ACP.
[Graphical view]
PfamiPF00501. AMP-binding. 2 hits.
PF13193. AMP-binding_C. 2 hits.
PF00668. Condensation. 3 hits.
PF00550. PP-binding. 2 hits.
[Graphical view]
SMARTiSM00823. PKS_PP. 2 hits.
[Graphical view]
SUPFAMiSSF47336. SSF47336. 2 hits.
TIGRFAMsiTIGR01733. AA-adenyl-dom. 2 hits.
TIGR01720. NRPS-para261. 1 hit.
PROSITEiPS50075. ACP_DOMAIN. 2 hits.
PS00455. AMP_BINDING. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q54959-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVPDDARLP LTAAQLGIWF AQARDPHSPV FNTGEYVELT GGLDADRFEA
60 70 80 90 100
ALRATVARTD ALRLRFHTDA EGTVTQSVAD DVPFTLHRVD VSAEDDPAAA
110 120 130 140 150
ADAWMRDVIA RPLDVTCGRP LFTQALFTLG PGRHRWFQHV HHLLLDGYGF
160 170 180 190 200
RLVAERVAAA YRAGAEAGDA EAGDTEPGIR DLLAAEADWR ASDAYAQDRA
210 220 230 240 250
HWLATPRHTP VTLAGTTAPG APGALRRTAS AGPEVLAGLD AVARAAETGR
260 270 280 290 300
QVAFPAAVAA YVQWLTGERT VTLGMPVTAR RTSAARRAPG TVANVPALHV
310 320 330 340 350
EPRPAAPLAE LVASVRDALE PLLRHQRYPY EEARRELGAV GERAYGPVVN
360 370 380 390 400
VMPYGRALDF GGPAASVHPV STGPVEDLKF SVYEEPDGSG ARIDLEANAA
410 420 430 440 450
VYGESETDAH LARFVRFLGA FAEAGPDTPL GRIHAAAPAA PAAAAPTTGG
460 470 480 490 500
PALHTLFAAR AAATPHAVAV SHDGDHLTYA QLDARANRLA HRLVEQGAGP
510 520 530 540 550
ERLVALTLPR SLDLVVALLA VLKSGAAYLP LDPDYPADRL AWMLEDAAPV
560 570 580 590 600
LVLDPQAMTE DLAGYPDTAP RTAVDGAHPA YVIYTSGSTG RPKGVVIPHS
610 620 630 640 650
NVVRLFTSTD HWFGFGPDDV WTLFHSYAFD FSVWEIWGAL LHGGRLVVVP
660 670 680 690 700
YHVSRSPGDF LDLLAREKVT VLNQTPTAFH QLDAADRART AAPELALRYV
710 720 730 740 750
VFGGEALDVA RLADWYARRG TAARLVNMYG ITETTVHVTH APLGPGHAVP
760 770 780 790 800
GTPSLLGGPI PDLTPRVLDA ALRPVPPGFT GELYVAGAGL ARGYLNRPAL
810 820 830 840 850
TAQRFPADPY GAPGTRMYRT GDLVRHLDDG TYAYLGRGDD QVKIRGFRIE
860 870 880 890 900
LGEIENVLAT HPGVAQAAAV VREDRHGDLR LAAYAVPTPG TEPDVAGWRA
910 920 930 940 950
LLAGQLPAHS LPASFTLLAA LPLTANGKLD RAALPAPQAP APETADEPAP
960 970 980 990 1000
AADPGEAALR RIFADTLGTP RVGADSDFFT LGGHSLLAGR LIAAVRDTLG
1010 1020 1030 1040 1050
AEITIQDLFE APTPAGLAAR VRTAATGRPP LVPRDHGDGP RPTSYAQHRM
1060 1070 1080 1090 1100
WVLREVEGAA PTYNMPLALR LSGTLNRTAL RAALYDVVVR HESLRTVYPR
1110 1120 1130 1140 1150
GEHGVTPRLL PPEQARPWVI ESRVDDEQLP AALTAAAREP FNLDCQLPIR
1160 1170 1180 1190 1200
AHLFTLPGGD SVLLLLMHHV AGDGWSLRPL LGDLSTAYAA RLAARAPDFP
1210 1220 1230 1240 1250
PLPVSYADFA VWQRELLGDE HDPDSLAARQ LAHWESTLAG LPDQLELPAD
1260 1270 1280 1290 1300
FPRPPVAEHR GGSVPLAVPP QLHARLDTFA RAHGATCHMV LQAALAALLT
1310 1320 1330 1340 1350
RLGAGTDIPI GCPTASRPDS ALDDLVGFFV NPVVLRADTS GDPTFTELLA
1360 1370 1380 1390 1400
RVRATALAAY AHQDVPFDRV VERLQPERSA ARHPLFQVVL SYQDFEARAH
1410 1420 1430 1440 1450
LKGLDVRRED VDFGVAKFDL TFNLVEHRGD GEEFAGIDGD LEYDTALYER
1460 1470 1480 1490 1500
ATAEALTGRL LRLLDAVVTD PQAPVGSHDL LEEAEHARLA AFNDTARPVP
1510 1520 1530 1540 1550
RAGLAELFTA QARRTPDAVA VVGDDGTELT YAELDARSGA LARRLAAAGA
1560 1570 1580 1590 1600
GRESAVAVLQ QRSVHLVVSL LAVLKAGGFY VPLNTRYPAD RMRLITADVK
1610 1620 1630 1640 1650
ARVLLTDRAT DTAHECRSWA GDADVLVVDE LPTGGEPLPV VPAHPHQLAY
1660 1670 1680 1690 1700
VMYTSGSTGN PKGVAITHGD VAALAADTCW RTGNQQRVLL HSPYSFDTSQ
1710 1720 1730 1740 1750
YELWVPLLSG GTVVVAPPGD LDTRALERAI VDGGVTGMWL TSGLFNLLAE
1760 1770 1780 1790 1800
ESPHCFTGVR EVWTGGDVVS PAAVARVLAA SPSTMVADGY GPTETTTFAT
1810 1820 1830 1840 1850
HHFMRAPWQQ ETTVPIGTPL DNTTCHVLDD RLRPVPPGVT GELYIGGSGL
1860 1870 1880 1890 1900
ARGYLNRPEL TAERFVADPY APGGRMYRTG DLVRLRRDGV LTFLGRADHQ
1910 1920 1930 1940 1950
VKVRGFRIEL GEIESVLGAH PGIAQSAVLV REDRPGDKRL VAYVVPAPGA
1960 1970 1980 1990 2000
TADATVLRRH VAAALPDYMV PAAFVPLDAL PLTGNGKLDR RALPVPDFGA
2010 2020 2030 2040 2050
ADSAGRAPRT PREELLAVLF AEVLGIEKVS IDDSFFDRGG DSIMVIQLVG
2060 2070 2080 2090 2100
RARRAGLLLN AAQIFEHKTV AQLAPVAETL ADTTREEPAA VAATGDVPLT
2110 2120 2130 2140 2150
PIMHWLRERG GPVDAFSQTM AVTVPAGLDR ERLVAALQTL IDHHDALRAV
2160 2170 2180 2190 2200
FSRDDADWTM RIEAPGTVDA ADWVRHVDAA GLDEQALAAL TTAEAAAARE
2210 2220 2230 2240 2250
RLAPFAGRGG QAVWLDAGPH RPGRLLLTLH HLVVDGVSWR ILLPDLKAAW
2260 2270 2280 2290 2300
EATAPGSAAP ALPPVTTSFR AWAHHLEQQA GCPERAAELA LWTGMLAAGS
2310 2320 2330 2340 2350
PPVTAQPLDG RLDTAATARG LTLTLDTTTT AALLTTAPAA FNGRVDDILL
2360 2370 2380 2390 2400
TAFALAVTDW RRRRGLGDSD AVLTDVEGHG REPGTSGAEL SRTVGWFTSL
2410 2420 2430 2440 2450
YPVRLALGTL DAADALAGGP AAGTAVKRIK EALRQIPDGG IGHGLLRHLD
2460 2470 2480 2490 2500
PRTGRSLAAL APYGTPPLGF NYLGRFPAEG ADGLWSAAPD AEAIGDGTDP
2510 2520 2530 2540 2550
RLPLAHAVEV NALTLDEPAG PRLKATWTFA GRLLDEPAVR DLGETWFRAL
2560 2570 2580 2590
NALVTHAERP EAGGITPSDL SLVQLSQDQI DQLEAAWKVS P
Length:2,591
Mass (Da):276,027
Last modified:November 1, 1996 - v1
Checksum:i79477DDA3715D6A6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X98690 Genomic DNA. Translation: CAA67248.1.
Y11548 Genomic DNA. Translation: CAA72311.1.
PIRiT30288.

Genome annotation databases

KEGGiag:CAA67248.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X98690 Genomic DNA. Translation: CAA67248.1.
Y11548 Genomic DNA. Translation: CAA72311.1.
PIRiT30288.

3D structure databases

ProteinModelPortaliQ54959.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi457429.SSDG_05434.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGiag:CAA67248.

Phylogenomic databases

eggNOGiCOG1020. LUCA.
KOiK16117.

Family and domain databases

Gene3Di1.10.1200.10. 2 hits.
InterProiIPR010071. AA_adenyl_domain.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
IPR001242. Condensatn.
IPR010060. NRPS_synth.
IPR020806. PKS_PP-bd.
IPR009081. PP-bd_ACP.
[Graphical view]
PfamiPF00501. AMP-binding. 2 hits.
PF13193. AMP-binding_C. 2 hits.
PF00668. Condensation. 3 hits.
PF00550. PP-binding. 2 hits.
[Graphical view]
SMARTiSM00823. PKS_PP. 2 hits.
[Graphical view]
SUPFAMiSSF47336. SSF47336. 2 hits.
TIGRFAMsiTIGR01733. AA-adenyl-dom. 2 hits.
TIGR01720. NRPS-para261. 1 hit.
PROSITEiPS50075. ACP_DOMAIN. 2 hits.
PS00455. AMP_BINDING. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Pristinamycin I biosynthesis in Streptomyces pristinaespiralis: molecular characterization of the first two structural peptide synthetase genes."
    de Crecy-Lagard V., Blanc V., Gil P., Naudin L., Lorenzon S., Famechon A., Bamas-Jacques N., Crouzet J., Thibaut D.
    J. Bacteriol. 179:705-713(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: SP92Imported.
  2. "Streptogramin B biosynthesis in Streptomyces pristinaespiralis and Streptomyces virginiae: molecular characterization of the last structural peptide synthase gene."
    de Crecy-Lagard V.A., Saurin W., Thibaut D., Gil P., Naudin L., Crouzet J., Blanc V.
    Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: SP92Imported.

Entry informationi

Entry nameiQ54959_STRPR
AccessioniPrimary (citable) accession number: Q54959
Secondary accession number(s): O05632
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.